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GTPase-activating protein for the ADP ribosylation factor family (Potential). Additionally we are shipping ADAP2 Antibodies (41) and ADAP2 Proteins (8) and many more products for this protein.
ArfGAP domain-containing protein 2 (ADAP2) is identified as a key novel scaffolding protein that integrates different modules of the RIG-I (show DDX58 ELISA Kits) pathway, located at distinct subcellular locations, and mediates cellular antiviral type I interferon (show IFNA ELISA Kits) production.
Data suggest ADAP2 (an interferon-beta (show IFNB1 ELISA Kits) stimulated gene) disrupts pathogenic internalization of some RNA viruses/virions (dengue, vesicular stomatitis) by altering ADP ribosylation factor 6 (show ARF6 ELISA Kits)-mediated processes including up-regulation of pinocytosis.
Centaurin-alpha (show ADAP1 ELISA Kits) interacts with beta-tubulin (show TUBB ELISA Kits) and stabilizes microtubules.
The human gene for centaurin alpha 2 is located on chromosome 17, position 17q11.2, near the neurofibromatosis 1 (NF1 (show NF1 ELISA Kits)) locus and concentrated at the plasma membrane.
ADAP2 has a role in heart development, and might be a reliable candidate gene for the occurrence of cardiovascular malformations in patients with NF1 (show NF1 ELISA Kits) microdeletion.
GTPase-activating protein for the ADP ribosylation factor family (Potential). Binds phosphatidylinositol 3,4,5- trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4). Possesses a stoichiometry of two binding sites for InsP4 with identical affinity.
centaurin, alpha 2
, ArfGAP with dual PH domains 2
, centaurin-alpha 2 protein
, arf-GAP with dual PH domain-containing protein 2
, centaurin beta
, Centaurin-alpha2 protein