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anti-ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2) Antibodies

The protein encoded by AGAP2 belongs to the centaurin gamma-like family. Additionally we are shipping ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 Kits (9) and ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
AGAP2 116986 Q99490
AGAP2 216439 Q3UHD9
AGAP2 65218 Q8CGU4
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Top anti-ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 Antibodies at antibodies-online.com

Showing 10 out of 101 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB CENTG1 Antibody (C-term) western blot analysis in mouse brain tissue lysates (35µg/lane).This demonstrates the CENTG1 antibody detected the CENTG1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of PIKE in mouse brain tissue with this product at 10 μg/ml. Western blot analysis of PIKE in mouse brain cell lysates with this product at (A) 0.5, (B) 1, and (C) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-CENTG1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: THP-1 cell lysate WB Suggested Anti-CENTG1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: THP-1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB CENTG1 Antibody (C-term) (ABIN654901) western blot analysis in mouse brain tissue lysates (35 µg/lane). This demonstrates the CENTG1 antibody detected the CENTG1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot using Protein A purified anti-AGAP2 antibody shows detection of AGAP2 recombinant protein in transfected HEK293 cell lysates. No specific band staining is noted in mock transfected cell lysates (empty vector). The membrane was probed with the primary antibody diluted to 1:10,000. 100 μg Log in to see 2 to 3 Days
$369.00
Details
Human Goat Un-conjugated IHC (p), ELISA, WB Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IF, IHC (p), ELISA, WB Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with AGAP2 antibody ABIN214332 at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details

AGAP2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 Antibodies

  1. Human Polyclonal AGAP2 Primary Antibody for EIA, WB - ABIN950297 : Zhu, Wu, Kim, Wang, Daaka, Nie: Arf GTPase-activating protein AGAP2 regulates focal adhesion kinase activity and focal adhesion remodeling. in The Journal of biological chemistry 2009 (PubMed)
    Show all 5 references for ABIN950297

  2. Human Polyclonal AGAP2 Primary Antibody for EIA, IHC (p) - ABIN500501 : Ye, Hurt, Wu, Fang, Luo, Hong, Blackshaw, Ferris, Snyder: Pike. A nuclear gtpase that enhances PI3kinase activity and is regulated by protein 4.1N. in Cell 2001 (PubMed)
    Show all 4 references for ABIN500501

  3. Human Polyclonal AGAP2 Primary Antibody for EIA, WB - ABIN401036 : Nie, Fei, Premont, Randazzo: The Arf GAPs AGAP1 and AGAP2 distinguish between the adaptor protein complexes AP-1 and AP-3. in Journal of cell science 2005 (PubMed)
    Show all 3 references for ABIN401036

  4. Human Polyclonal AGAP2 Primary Antibody for WB - ABIN452299 : Liu, Jang, Liu, Cheng, Peng, Yepes, Li, Matthews, Watts, Asano, Hara-Nishimura, Luo, Ye: Neuroprotective actions of PIKE-L by inhibition of SET proteolytic degradation by asparagine endopeptidase. in Molecular cell 2008 (PubMed)

More Antibodies against ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 Interaction Partners

Human ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2) interaction partners

  1. Mutation of Fyn (show FYN Antibodies) phosphorylation sites on PIKE-A, depletion of Fyn (show FYN Antibodies), or pharmacological inhibition of Fyn (show FYN Antibodies) blunts the association between PIKE-A and AMPK (show PRKAA1 Antibodies), resulting in loss of its inhibitory effect on AMPK (show PRKAA1 Antibodies).

  2. expression of PLC-gamma1 (show PLCG1 Antibodies) and PIKE positively correlated with the tumor differentiation of oral squamous cell carcinoma.

  3. PIKE reduction rescued PI3K (show PIK3CA Antibodies)-dependent and -independent neuronal defects in fragile X (show FMR1 Antibodies) syndrome.

  4. In this review the CENTG1 gene is amplified in a variety of human cancers which lead to the enhancement of tumor invasion.

  5. AGAP2 plays a role in the signalling and recycling of beta2-adrenergic receptors.

  6. Fyn (show FYN Antibodies) regulates the activity of the adipogenic transcription factor signal transducer and activator of transcription 5a (STAT5a (show STAT5A Antibodies)) through enhancing its interaction with the GTPase (show RACGAP1 Antibodies) phosphoinositide 3-kinase enhancer A (PIKE-A).

  7. PIKE is highly expressed in human squamous cell carcinoma and has a critical role in EGF (show EGF Antibodies)-induced squamous cell carcinoma proliferation.

  8. The presence of heterogeneous missense mutations of GGAP2 in prostate cancer was associated with aggressive clinical behavior.

  9. PIKE is a critical factor in controlling synaptic AMPA (show GRIA3 Antibodies) receptor insertion.

  10. Akt (show AKT1 Antibodies)-phosphorylated PIKE-A inhibits UNC5B (show UNC5B Antibodies)-induced apoptosis in cancer cell lines in a p53 (show TP53 Antibodies)-dependent manner. [PIKE-A]

Mouse (Murine) ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2) interaction partners

  1. PIKE plays pivotal roles to advance oligodendroglia development and myelinogenesis through Akt (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies) activation.

  2. Results demonstrate that the integrity of PIKE signaling is essential for protecting the neurons from excitotoxicity-stimulated damage both in vitro and in vivo.

  3. Fyn (show FYN Antibodies) regulates the activity of the adipogenic transcription factor signal transducer and activator of transcription 5a (STAT5a (show STAT5A Antibodies)) through enhancing its interaction with the GTPase (show RACGAP1 Antibodies) phosphoinositide 3-kinase enhancer A (PIKE-A).

  4. PIKE is a critical factor in controlling synaptic AMPA (show GRIA3 Antibodies) receptor insertion.

  5. data established the critical role of PIKE in regulating neuronal survival and development by substantiating the PI3K/Akt (show AKT1 Antibodies) pathway.

  6. PIKE-A is required for prolactin (show PRL Antibodies)-mediated STAT5a (show STAT5A Antibodies) activation in mammary gland development.

  7. PIKE knockout mice show augmented lipid oxidation, which is accompanied by enhanced AMPK (show PRKAA1 Antibodies) phosphorylation in muscle and adipose tissue and is implicated in obesity and diabetes development.

  8. PIKE-L acts as a downstream survival effector for netrin-1 (show NTN1 Antibodies) through UNC5B (show UNC5B Antibodies) in the nervous system

ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2) Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with AGAP2

  • ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 (AGAP2) antibody
  • ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 (agap2) antibody
  • ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 (Agap2) antibody
  • Centg1 antibody
  • GGAP2 antibody
  • mKIAA0167 antibody
  • Pike antibody
  • zgc:153779 antibody

Protein level used designations for AGAP2

arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 , Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 2 , GTP-binding and GTPase activating protein 2 , centaurin, gamma 1 , cnt-g1 , phosphatidylinositol 3-kinase enhancer , phosphatidylinositol-3-kinase enhancer , phosphoinositide 3-kinase enhancer , AGAP-2 , PIKE , centaurin-gamma-1 , nuclear GTPase PIKE

GENE ID SPECIES
504833 Bos taurus
565109 Danio rerio
116986 Homo sapiens
216439 Mus musculus
65218 Rattus norvegicus
100050853 Equus caballus
481130 Canis lupus familiaris
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