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anti-Argininosuccinate Synthase 1 (ASS1) Antibodies

The protein encoded by ASS1 catalyzes the penultimate step of the arginine biosynthetic pathway. Additionally we are shipping Argininosuccinate Synthase 1 Proteins (19) and Argininosuccinate Synthase 1 Kits (15) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ASS1 445 P00966
ASS1 25698 P09034
ASS1 11898 P16460
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Top anti-Argininosuccinate Synthase 1 Antibodies at antibodies-online.com

Showing 10 out of 89 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Goat Un-conjugated EIA, IF, IHC (p), IP, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB ASS1 Antibody (C-term) immunohistochemistry analysis in formalin fixed... ASS1 Antibody (C-term) western blot analysis in Jurkat cell line lysat... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$423.50
Details
Human Mouse Un-conjugated EIA, FACS, IF, WB 0.1 mg Log in to see 6 to 8 Days
$423.50
Details
Human Mouse Un-conjugated ICC, FACS, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green... Figure 2: Flow cytometric analysis of Jurkat cells using ASS1 mouse mA... 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Mouse Un-conjugated IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green... Figure 2: Immunohistochemical analysis of paraffin-embedded cervical c... 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Goat Un-conjugated IP, ELISA, WB ABIN190834 (0.03µg/ml) staining of Human Kidney lysate (35µg protein i... 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB ASS1 Antibody (C-term) (ABIN656537) immunohistochemistry analysis in f... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated EIA, IHC (p), IP, WB Immunohistochemistry Image: Human Kidney: Formalin-Fixed, Paraffin-Emb... Immunohistochemistry Image: Human Liver: Formalin-Fixed, Paraffin-Embe... 50 μg Log in to see 6 to 8 Days
$500.50
Details

ASS1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Top referenced anti-Argininosuccinate Synthase 1 Antibodies

  1. Human Polyclonal ASS1 Primary Antibody for EIA, IHC (p) - ABIN950542 : Hozyasz, Mostowska, Wojcicki, Lianeri, Jagodzinski: Polymorphic variants of genes related to arginine metabolism and the risk of orofacial clefts. in Archives of oral biology 2010 (PubMed)
    Show all 5 references for ABIN950542

  2. Human Polyclonal ASS1 Primary Antibody for IP, ELISA - ABIN190834 : Hao, Xie, Gross: Argininosuccinate synthetase is reversibly inactivated by S-nitrosylation in vitro and in vivo. in The Journal of biological chemistry 2004 (PubMed)
    Show all 2 references for ABIN190834

  3. Human Monoclonal ASS1 Primary Antibody for ICC, FACS - ABIN969502 : Laróvere, Angaroni, Antonozzi, Bezard, Shimohama, de Kremer: Citrullinemia type I, classical variant. Identification of ASS-p~G390R (c.1168G>A) mutation in families of a limited geographic area of Argentina: a possible population cluster. in Clinical biochemistry 2009 (PubMed)

  4. Human Polyclonal ASS1 Primary Antibody for EIA, WB - ABIN452770 : Engel, Höhne, Häberle: Mutations and polymorphisms in the human argininosuccinate synthetase (ASS1) gene. in Human mutation 2009 (PubMed)

  5. Cow (Bovine) Polyclonal ASS1 Primary Antibody for EIA, IF - ABIN374809 : Corbin, Pendleton, Solomonson, Eichler: Phosphorylation of argininosuccinate synthase by protein kinase A. in Biochemical and biophysical research communications 2008 (PubMed)

More Antibodies against Argininosuccinate Synthase 1 Interaction Partners

Human Argininosuccinate Synthase 1 (ASS1) interaction partners

  1. results show that ASS1 is elevated at the mRNA and protein levels in mesothelioma 3D spheroids and in human pleural mesotheliomas. We also have uncovered a survival role for ASS1

  2. results demonstrate that ASS1 downregulation is a novel mechanism supporting cancerous proliferation, and they provide a metabolic link between the urea cycle enzymes and pyrimidine synthesis

  3. More than 50 % of the high-grade pulmonary neuroendocrine carcinomas tested lack immunohistochemically detectable ASS, suggesting that they are auxotrophic for arginine and potential candidates for arginine deprivation therapy.

  4. Three novel splicing and missense mutations have been identified in the ASS1 gene in classical citrullinemia patients.

  5. ASS expression in gastric cancer was associated with a poor prognosis.

  6. we reviewed the English literature on mutations in the ASS and SLC25A13 (show slc25a13 Antibodies) genes, and their genotype-phenotype correlations to provide valuable insights into the molecular genetic background of citrullinemia--{REVIEW}

  7. Data indicate that argininosuccinate synthetase 1 (ASS1) abundance is a prognostic factor for overall breast cancer survival.

  8. Point mutation of ASS1, ASL (show ADSL Antibodies) and SLC25A13 (show slc25a13 Antibodies) is associated with citrullinemia.

  9. Aberrant loss of ASS1 strongly links to DNA methylation (show HELLS Antibodies) in neck nodal metastases of NPC (show NPC1 Antibodies) and significantly correlates with advanced T classification, and independently predicts worse DSS (show NR0B1 Antibodies) and DMFS in independent NPC (show NPC1 Antibodies) tissue specimens.

  10. Together with the observation that AS1 protein and mRNA levels decrease during wild-type infection, this work suggests that reduced AS1 activity is partially responsible for the metabolic program induced by infection.

Cow (Bovine) Argininosuccinate Synthase 1 (ASS1) interaction partners

  1. calcium-dependent phosphorylation of argininosuccinate synthase Ser (show SIGLEC1 Antibodies)-328 is mediated by PKCalpha (show PKCa Antibodies)

  2. dose-dependent reduction of ASS as a result of siRNA treatment corresponded to diminished capacity to produce NO, despite saturating levels of arginine in the medium; reduced expression of ASS resulted in loss of viability due to apoptosis

  3. In endothelial cells TNF-alpha (show TNF Antibodies) coordinately downregulates nitric oxide synthase (show NOS Antibodies) (eNOS (show NOS3 Antibodies)) and argininosuccinate synthase expression, resulting in a severely impaired citrulline-NO cycle.

  4. These results represent the first demonstration that vascular endothelial nitric oxide production can be regulated by dynamic argininosuccinate synthase phosphorylation.

Mouse (Murine) Argininosuccinate Synthase 1 (ASS1) interaction partners

  1. In diabetic mice, ablation of Ass resulted in diminished endothelium-derived nitric oxide-mediated vascular relaxation responses.

  2. cAMP-induced Ass1 expression is important in controlling the magnitude of decidualization through regulating L-Arg level.

  3. We demonstrate that the transgenic mouse system reported here has the merit of sensitivity and direct visualization advantage, and is ideal for annotating temporal and spatial expression profiles and the regulation mode of the ASS gene.

  4. Thus, extracellular arginine fuels rapid NO production in activated macrophages, and citrulline recycling via Ass1 and Asl (show ADSL Antibodies) is a fail-safe system that sustains optimum NO production.

  5. Partial argininosuccinate synthase ablation protects only in acute ethanol-induced liver injury by decreasing nitrosative stress but not in a more chronic scenario where oxidative stress and impaired fatty acid beta-oxidation are key events.

  6. Loss of Ass1 is associated with citrullinemia type I and other hyperammonemic syndromes.

Argininosuccinate Synthase 1 (ASS1) Antigen Profile

Protein Summary

The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of this gene cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with ASS1

  • argininosuccinate synthase 1 (ASS1) antibody
  • argininosuccinate synthetase 1 (ass1) antibody
  • argininosuccinate synthase 1 (ass1) antibody
  • argininosuccinate synthase 1 (Ass1) antibody
  • argininosuccinate synthetase 1 (Ass1) antibody
  • AA408052 antibody
  • Ass antibody
  • Ass-1 antibody
  • ASSA antibody
  • CTLN1 antibody
  • fold antibody
  • wu:fb95a04 antibody
  • wu:fc01e08 antibody
  • zgc:92051 antibody

Protein level used designations for ASS1

argininosuccinate synthetase 1 , argininosuccinate synthase , citrulline--aspartate ligase , arginosuccinate synthetase , argininosuccinate synthase 1 , argininosuccinate synthase-like , citrulline-aspartate ligase , citrullinemia , arginosuccinate synthetase 1

GENE ID SPECIES
414411 Sus scrofa
447864 Danio rerio
496645 Xenopus (Silurana) tropicalis
100218639 Taeniopygia guttata
100396479 Callithrix jacchus
100465731 Ailuropoda melanoleuca
100602356 Nomascus leucogenys
445 Homo sapiens
480693 Canis lupus familiaris
280726 Bos taurus
25698 Rattus norvegicus
417185 Gallus gallus
380488 Xenopus laevis
11898 Mus musculus
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