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E3 ubiquitin-protein ligase, which catalyzes polyubiquitination of target proteins together with ubiquitin- conjugating enzyme E2 UBE2L3. Additionally we are shipping Ariadne Homolog, Ubiquitin-Conjugating Enzyme E2 Binding Protein, 1 (Drosophila) Antibodies (32) and and many more products for this protein.
DNA damage induces an increase in ARIH1 protein levels and association of ARIH1 with 4EHP. In turn, this causes 4EHP recruitment to the mRNA cap, where it is known to compete with eIF4E (show EIF4E ELISA Kits).
Determined is the three-dimensional solution structure of the catalytic RING2 (show RNF2 ELISA Kits) domain from HHARI. It shows glimpses of a HECT E3 ligase.
TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexes.
HHARI is a marker of cellular proliferation associated with nuclear bodies.
Both parkin (show PARK2 ELISA Kits) and HHARI bind the same substrate proteins in cells and induce the formation of aggresomes.
UBCH7 (show UBE2L3 ELISA Kits) exhibits activity with the RING-in-between-RING (RBR) family of E3s that includes parkin (show PARK2 ELISA Kits) (also known as PARK2 (show PARK2 ELISA Kits)) and human homologue of ariadne (HHARI; also known as ARIH1)
the structure of the RING2 (show RNF2 ELISA Kits) from the RING-IBR-RING motif of HHARI and showed that RING2 (show RNF2 ELISA Kits) has a completely distinct topology from classical RINGs
Ndfip1 (show NDFIP1 ELISA Kits) regulates itch ligase activity and airway inflammation via UbcH7 (show UBE2L3 ELISA Kits).
E3 ubiquitin-protein ligase, which catalyzes polyubiquitination of target proteins together with ubiquitin- conjugating enzyme E2 UBE2L3. May play a role in protein translation by mediating polyubiquitination of EIF4E2, leading to its subsequent degradation (By similarity).
ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1
, ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)
, E3 ubiquitin-protein ligase arih1
, Protein ariadne-1 homolog
, E3 ubiquitin-protein ligase ARIH1
, ariadne, Drosophila, homolog of
, monocyte protein 6
, protein ariadne-1 homolog
, ubcH7-binding protein
, ubcM4-interacting protein
, ubiquitin-conjugating enzyme E2-binding protein 1
, UbcH7-binding protein
, UbcM4-interacting protein 77
, ariadne 1