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ARMCX3 encodes a member of the ALEX family of proteins which may play a role in tumor suppression. Additionally we are shipping Armadillo Repeat Containing, X-Linked 3 Antibodies (61) and Armadillo Repeat Containing, X-Linked 3 Kits (12) and many more products for this protein.
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reduction of Alex3 correlates with the development of non-small cell lung cancer and predicts adverse clinical outcome of non-small cell lung cancer patients. The effect of Alex3 on inhibiting invasion and migration may attribute to upregulation of E-cadherin (show CDH1 Proteins) expression through AKT (show AKT1 Proteins)-Slug (show SNAI2 Proteins) pathway inactivation.
The Wnt (show WNT2 Proteins) pathway regulates mitochondrial distribution and dynamics through Alex3 protein degradation.
Sox10 (show SOX10 Proteins) is a membrane-associated factor whose transcriptional function is increased by direct interactions with ARMCX3
This gene encodes a member of the ALEX family of proteins which may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and a single Armadillo (arm) repeat. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members on the X chromosome. Three transcript variants encoding the same protein have been identified for this gene.
armadillo repeat containing, X-linked 3
, Armadillo repeat-containing X-linked protein 3
, armadillo repeat-containing X-linked protein 3-like
, ARM protein lost in epithelial cancers on chromosome X 3
, arm protein lost in epithelial cancers, X chromosome, 3
, armadillo repeat-containing X-linked protein 3