You are viewing an incomplete version of our website. Please click to reload the website as full version.

Arrestin, beta 2 Proteins (ARRB2)

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Additionally we are shipping Arrestin 3 Antibodies (72) and Arrestin 3 Kits (37) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ARRB2 409 P32121
ARRB2 25388 P29067
ARRB2 216869 Q91YI4
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Arrestin 3 Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag,GST tag 100 μg Log in to see 11 to 13 Days
$792.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,138.67
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,169.83
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$967.75
Details

ARRB2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
, ,
Rat (Rattus)

Mouse (Murine)

Top referenced Arrestin 3 Proteins

  1. Human Arrestin 3 Protein expressed in Wheat germ - ABIN1345726 : Quack, Woznowski, Potthoff, Palmer, Königshausen, Sivritas, Schiffer, Stegbauer, Vonend, Rump, Sellin: PKC alpha mediates beta-arrestin2-dependent nephrin endocytosis in hyperglycemia. in The Journal of biological chemistry 2011 (PubMed)

More Proteins for Arrestin, beta 2 (ARRB2) Interaction Partners

Human Arrestin, beta 2 (ARRB2) interaction partners

  1. beta-arrestins regulate oxidative stress in a Nox4 (show NOX4 Proteins)-dependent manner and increase fibrosis in heart failure.

  2. Results demonstrate that betaArr2 signaling may be an important pathway for TAAR1 function and that the activation of the TAAR1-D2R complex negatively modulates GSK3b signaling

  3. Role for engagement of BARR2 by the transactivated EGFR in agonist-specific regulation of delta receptor activation of ERK1/2

  4. Data suggest that thrombin (show F2 Proteins) can directly activate PAR2 (show F2RL1 Proteins) vasorelaxation, signal transduction (stimulating both calcium and MAP kinase (show MAPK1 Proteins) responses), and triggering beta-arrestin recruitment (both beta-arrestin 1 (show ARRB1 Proteins) and 2).

  5. a beta-arrestin signalling cycle that is catalytically activated by the GPCR and energetically coupled to the endocytic machinery

  6. The rare variants in ARRB2 were significantly associated with smoking status.

  7. analysis of the crystal structure of the rhodopsin-arrestin (show SAG Proteins) complex

  8. In this study, we aimed to exploit an in vitro model system of BPH in order to better understand the mechanisms of alpha-AR signaling in prostatic hyperplasia.

  9. interaction of beta-arrestin with GPCRs, and the beta-arrestin conformational changes in real time and in living human cells, using a series of fluorescence resonance energy transfer (FRET)-based beta-arrestin2 biosensors

  10. ARRB2 is not upregulated in inflammation-associated hepatocellular carcinoma (HCC) and paracancerous tissues.

Cow (Bovine) Arrestin, beta 2 (ARRB2) interaction partners

  1. The fraction of arrestin2 molecules found in clusters larger than 100nm correlates with the magnitude of ligand-induced CCR5 internalization.

  2. K2A mutations in arrestin-1 (show SAG Proteins), -2, and -3 significantly reduced their binding to active phosphorhodopsin.

  3. Results reveal that multiple intramolecular interactions coordinately regulate arrestin2 interaction with clathrin, highlighting this interaction as a critical step in regulating receptor trafficking.

Mouse (Murine) Arrestin, beta 2 (ARRB2) interaction partners

  1. [beta]-arrestin2 regulates intestinal mucosal inflammation under both homeostatic and colitic conditions. Its mode of action involves negative regulation of T-cell activation and its requirement for induction of regulatory T cells.

  2. Results suggest that the antipruritic effects of kappa opioid receptor (show OPRK1 Proteins) agonists may not require betaarrestin2

  3. that pro- and anti-inflammatory activities of beta-arrestin2 are determined by beta-arrestin2 ubiquitination and that changes in USP20 (show USP20 Proteins) expression and/or activity can therefore regulate inflammatory responses

  4. This shows that mood stabilizers lamotrigine, lithium and valproate can exert behavioral effects in mice by disrupting the beta-arrestin 2-mediated regulation of Akt/GSK3 signaling by D2 dopamine receptors.

  5. findings show for the first time that Ang II (show AGT Proteins) receptor signaling to beta-arrestin regulates ARF6 (show ARF6 Proteins) activation. These proteins together control receptor endocytosis and ultimately cell migration.

  6. These results reveal that the protective effect of deficiency of Arrb2 is due to loss of negative regulation of Akt (show AKT1 Proteins).

  7. that Insulin-like growth factor-1 (show IGF1 Proteins) contributes to the mucosal repair by beta-arrestin2-mediated extracellular signal-regulated kinase signaling in experimental colitis

  8. ARRB2 is not involved in hepatocellular carcinogenesis.

  9. morphine activated JNK2 through an arrestin-independent Src- and PKC-dependent mechanism, whereas fentanyl activated JNK2 through a Src-GRK3/arrestin-2-dependent and PKC-independent mechanism.

  10. Arrb2 is required for potentiation of odorant receptor responses by Chrm3 (show CHRM3 Proteins).

Xenopus laevis Arrestin, beta 2 (ARRB2) interaction partners

  1. Arrb2 physically interacts with the beta subunit (show POLG Proteins) of trimeric G-proteins and Dishevelled (show DVL2 Proteins), the interaction between arrb2 and Dishevelled (show DVL2 Proteins) is promoted by the beta/gamma subunits of trimeric G-proteins.

Zebrafish Arrestin, beta 2 (ARRB2) interaction partners

  1. results suggest that a functional interaction between beta-arrestin 2 and Smoothened may be critical to regulate hedgehog (show SHH Proteins) signaling in zebrafish development

Arrestin 3 (ARRB2) Protein Profile

Protein Summary

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Arrestin, beta 2 Proteins (ARRB2)

  • arrestin, beta 2 (ARRB2)
  • arrestin, beta 2 (arrb2)
  • arrestin, beta 2 (Arrb2)
  • arrestin, beta 2b (arrb2b)
  • AI326910 protein
  • ARB2 protein
  • ARR2 protein
  • arrb2 protein
  • arrestin protein
  • AW122872 protein
  • BARR2 protein
  • BARRES protein
  • betaarr2 protein
  • zgc:64007 protein

Protein level used designations for Arrestin, beta 2 Proteins (ARRB2)

arrestin beta 2 , arrestin, beta 2 , arrestin 2 , beta-Arrestin 2 , arrestin beta-2 , beta-arrestin-2 , beta-arrestin-2-like , arrestin 3 , arrestin-3 , beta arr2 , beta-arrestin 2 , ARRB2b2

GENE ID SPECIES
454450 Pan troglodytes
709399 Macaca mulatta
100101741 Xenopus (Silurana) tropicalis
100172117 Pongo abelii
100387113 Callithrix jacchus
100478601 Ailuropoda melanoleuca
100599882 Nomascus leucogenys
409 Homo sapiens
25388 Rattus norvegicus
281638 Bos taurus
216869 Mus musculus
444007 Xenopus laevis
607262 Canis lupus familiaris
100170767 Sus scrofa
100341204 Oryctolagus cuniculus
100072892 Equus caballus
100716149 Cavia porcellus
101112493 Ovis aries
394099 Danio rerio
Selected quality suppliers for Arrestin 3 Proteins (ARRB2)
Did you look for something else?