anti-Arsenic (+3 Oxidation State) Methyltransferase (AS3MT) Antibodies

AS3MT catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to trivalent arsenical and may play a role in arsenic metabolism (Lin et al., 2002 [PubMed 11790780]).[supplied by OMIM, Mar 2008].. Additionally we are shipping AS3MT Kits (15) and AS3MT Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
AS3MT 57412 Q9HBK9
AS3MT 57344 Q91WU5
AS3MT 140925 Q8VHT6
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Top anti-AS3MT Antibodies at antibodies-online.com

Showing 10 out of 23 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-AS3MT Antibody Titration: 0.2-1 ug/mlPositive Control: Jurkat cell lysate WB Suggested Anti-AS3MT  Antibody Titration: 0.2-1 µg/mL  Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Armenian Hamster Goat Un-conjugated IHC (p), IHC, ELISA, WB Immunohistochemistry-Paraffin: AS3MT Antibody [ABIN249705] - (3.8ug/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Human Rabbit Un-conjugated WB Line1, mouse heart lysate; Line2, mouse liver lysate probed with Rabbit Anti-CYT19 Polyclonal Antibody, Unconjugated (ABIN2559676) at 1:300 in 4˚C. Followed by conjugation to secondary antibody at 1:5000 for 90min at 37˚C. 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Goat Un-conjugated IHC (p), ELISA Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
$451.00
Details
Human Goat Un-conjugated EIA, IHC (p) Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit HRP WB   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Biotin WB   100 μL Log in to see 14 to 21 Days
$383.90
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunofluorescence: AS3MT Antibody [NBP1-85354] - Staining of human cell line U-251MG shows positivity in mitochondria. Immunohistochemistry-Paraffin: AS3MT Antibody [NBP1-85354] - Staining of human small intestine shows cytoplasmic positivity in glandular cells. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: AS3MT Antibody [NBP1-85355] - Staining of human cell line U-251 MG shows positivity in nucleus & nucleoli. Immunohistochemistry: AS3MT Antibody [NBP1-85355] - Staining of human duodenum shows strong cytoplasmic positivity in glandular cells. 0.1 mL Log in to see 7 to 9 Days
$439.69
Details

AS3MT Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
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Mouse (Murine)


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Rat (Rattus)


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Top referenced anti-AS3MT Antibodies

  1. Armenian Hamster Polyclonal AS3MT Primary Antibody for IHC (p), IHC - ABIN249705 : Lin, Shi, Nix, Styblo, Beck, Herbin-Davis, Hall, Simeonsson, Thomas: A novel S-adenosyl-L-methionine:arsenic(III) methyltransferase from rat liver cytosol. in The Journal of biological chemistry 2002 (PubMed)
    Show all 2 references for 249705

More Antibodies against AS3MT Interaction Partners

Human Arsenic (+3 Oxidation State) Methyltransferase (AS3MT) interaction partners

  1. AS3MT and N6AMT1 (show N6AMT1 Antibodies) polymorphisms and urinary arsenic metabolites (%iAs, %MMA, %DMA (show HLA-DMA Antibodies)) in 722 subjects from an arsenic-cancer case-control study in a uniquely exposed area in northern Chile, were examined.

  2. Risk alleles spanning multiple genes across the 10q24.32 schizophrenia-related locus are associated in the human brain selectively with an increase in the expression of both BLOC-1 (show BLOC1S1 Antibodies) related complex subunit 7 (show CCT7 Antibodies) (BORCS7) and a previously uncharacterized, human-specific arsenite methyltransferase (AS3MT) isoform (AS3MTd2d3).

  3. A joint dose-response effect was identified for a AS3MT high-risk haplotype and inefficient arsenic methylation capacity on developmental delay.

  4. genome-wide association study in population in United States (AZ, OK, SD, ND): Data suggest SNPs in AS3MT (rs17878846, rs10509760) partly explain inter-individual variability in susceptibility to arsenic poisoning (and urine arsenic species patterns).

  5. The present study found that rs3740400 in As3MT and rs156697 in GSTO2 were strongly associated with the arsenic species (%iAs, %MMA and MMA/iAs and DMA/MMA ratios) in urine of the occupationally exposed workers and they may influence methylation capacity.

  6. analysis of the functional roles of GSH and the crucial Cys (show DNAJC5 Antibodies) residues in iAs3+ methylation catalyzed by hAS3MT

  7. a strong signal of positive selection in the main arsenic methyltransferase AS3MT gene, which has been previously associated with lower concentrations of the most toxic product of arsenic metabolism monomethylarsonic acid.

  8. This study's results provide preliminary evidence for the over-transmission of the A allele at the AS3MT rs11191454 polymorphism in Attention Deficit Hyperactivity Disorder.

  9. Genetic variation in AS3MT gene is associated with arsenic metabolism and risk of basal cell carcinoma.

  10. Two SNPs, AS3MT 12390 (rs3740393) and 14458 (rs11191439) were consistently related to arsenic methylation regardless of the populations examined for the analysis.

Mouse (Murine) Arsenic (+3 Oxidation State) Methyltransferase (AS3MT) interaction partners

  1. Data, including date from studies in knockout mice, suggest that As3mt is involved in energy metabolism in a sex-specific manner, independent of inorganic arsenic poisoning; thus, As3mt may be involved in cellular processes beyond methylation of inorganic arsenic.

  2. Oxidative damage and Ogg1 (show OGG1 Antibodies) deficient background exacerbate repair deficiencies.. Overexpression of the arsenic metabolizing enzyme As3mt acts as adaptive mechanism.

  3. Simple hyperplasia of the bladder epithelium was detected in all As3mt KO mice treated with sodium arsenite.

  4. Rat, mouse and human are efficient methylators of inorganic arsenic. Findings suggest a role for AS3MT in the methylation of inorganic arsenic.

AS3MT Antigen Profile

Protein Summary

AS3MT catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to trivalent arsenical and may play a role in arsenic metabolism (Lin et al., 2002

Gene names and symbols associated with AS3MT

  • arsenic (+3 oxidation state) methyltransferase (AS3MT) antibody
  • arsenic (+3 oxidation state) methyltransferase (as3mt) antibody
  • arsenic (+3 oxidation state) methyltransferase (ABO_2182) antibody
  • arsenic (+3 oxidation state) methyltransferase (As3mt) antibody
  • 2310045H08Rik antibody
  • AS3MT antibody
  • Cyt19 antibody
  • DKFZp469A1918 antibody
  • zgc:136933 antibody

Protein level used designations for AS3MT

arsenic (+3 oxidation state) methyltransferase , arsenite methyltransferase , arsenite methyltransferase-like , S-adenosyl-L-methionine:arsenic(III) methyltransferase , S-adenosylmethionine:arsenic (III) methyltransferase , methylarsonite methyltransferase , methyltransferase cyt19 , methyltransferase Cyt19

GENE ID SPECIES
423870 Gallus gallus
450703 Pan troglodytes
486865 Canis lupus familiaris
505482 Bos taurus
664699 Danio rerio
714122 Macaca mulatta
788389 Bos taurus
100157047 Sus scrofa
100173119 Pongo abelii
100216291 Xenopus (Silurana) tropicalis
100286452 Salmo salar
100341970 Oryctolagus cuniculus
100477280 Ailuropoda melanoleuca
4212516 Alcanivorax borkumensis SK2
100528174 Ictalurus punctatus
57412 Homo sapiens
57344 Mus musculus
140925 Rattus norvegicus
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