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AHR encodes a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. Additionally we are shipping Aryl Hydrocarbon Receptor Antibodies (253) and Aryl Hydrocarbon Receptor Kits (43) and many more products for this protein.
Showing 8 out of 9 products:
Human Aryl Hydrocarbon Receptor Protein expressed in Wheat germ - ABIN1344642
van den Bogaard, Bergboer, Vonk-Bergers, van Vlijmen-Willems, Hato, van der Valk, Schröder, Joosten, Zeeuwen, Schalkwijk: Coal tar induces AHR-dependent skin barrier repair in atopic dermatitis. in The Journal of clinical investigation 2013
Show all 2 references for ABIN1344642
Identified structural features of AHR1beta associated with low TCDD sensitivity. Substitution of the entire ligand binding domain with the corresponding sequence from mouse AHR(b-1) dramatically increased TCDD responsiveness in transactivation assays.
Transient AHR activation and cytochrome P450 1A (CYP1A) induction in livers occurred during ANIT-induced hepatobiliary impairment in medaka.
Also, overexpression of AHR facilitated cell proliferation and migration via up-regulation of NDRG1.
our data from human subjects suggest that AhR expression levels could serve as an additional, new predictor of vessel aging.
AHR may function intrinsically as a xenosensor as well as a ligand-dependent transcription factor in human pluripotent stem cell-derived hepatocyte-like cells.
Activation of AhR in the placenta might impair trophoblast cell proliferation and migration, possibly leading to the occurrence of unexplained recurrent spontaneous abortion.
the AhR-G1661A transition may affect AhR-transactivation domain interaction.
effects resulted from the activation of AhR as shown by RNA interference, chromatin immunoprecipitation and the use of several AhR ligands
AHR plays an important role in development of cells with cancer stem cell-like qualities and that environmental AHR ligands may exacerbate breast cancer by enhancing expression of these properties.
Results determined that constitutive AhR expression coupled to BRCA-1 promoter CpG hypermethylation may be predictive markers of ERalpha (show ESR1 Proteins)-negative breast tumor development.
Lack of association between the aryl hydrocarbon receptor rs2066853 polymorphism and breast cancer
Report NcoA2 (show NCOA2 Proteins)-regulation of the AhR-ARNT (show ARNT Proteins)-HIF-1a (show HIF1A Proteins) interaction.
steroid hormones, AhR and estrogen receptor beta (show ESR2 Proteins) are affected by TCDD and genistein in granulosa cells of medium porcine follicles
AHR mRNA expression in follicular, theca, and granulosa cells suggest the involvement of AHR in the modulation of reproductive processes in the porcine ovary.
Results suggest that AhR activity plays a role in regulating granule neuron number and differentiation, possibly by coordinating this granule neuron precursor cell developmental transition
AhR plays an important role in myocardial ischaemic injury and inflammation promotion, and baicalin attenuates myocardial necrosis and remodeling though suppression of the inflammatory response by inhibiting AhR activation.
Developmental AHR activation by pollutants, and other exogenous ligands, increases the likelihood that Gnaq knockout mice will develop autoimmune diseases later in life.
AhR and NF-kappaB/Rel protein binding profile within the 3'IghRR mediates the inhibitory effects of TCDD on Ig expression and therefore antibody levels.
AhR is a negative regulator of profibrotic signals in the gut (show GUSB Proteins).
Data (including data from studies in knockout/mutant mice) suggest expression of Ahr and its translocation into nucleus are necessary for Ahr ligand-mediated synergistic induction of Ccl20 (show CCL20 Proteins) [chemokine (C-C motif) ligand 20 (show CCL20 Proteins)]; here, TCDD is Ahr ligand.
AHR plays protective roles against high-fat diet-induced hepatic steatosis and the subsequent lipotoxicity via direct transcriptional regulation of Socs3 (show SOCS3 Proteins) gene expression.
This study thus indicates a critical role of TCDD-induced AhR activation in the regulation of non-eosinophilic airway inflammation
findings reported here underscore the conclusion that AHR signaling in the developing heart is one potential target of environmental factors associated with cardiovascular disease
This gene encodes a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Its ligands included a variety of aromatic hydrocarbons.
aryl hydrocarbon receptor
, aryl hydrocarbon receptor 1
, aryl hydrocarbon receptor-like
, ah receptor
, aromatic hydrocarbon receptor
, class E basic helix-loop-helix protein 76
, Ah receptor
, dioxin receptor