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AHR encodes a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. Additionally we are shipping Aryl Hydrocarbon Receptor Antibodies (242) and Aryl Hydrocarbon Receptor Kits (53) and many more products for this protein.
Showing 8 out of 9 products:
Human Aryl Hydrocarbon Receptor Protein expressed in Wheat germ - ABIN1344642
van den Bogaard, Bergboer, Vonk-Bergers, van Vlijmen-Willems, Hato, van der Valk, Schröder, Joosten, Zeeuwen, Schalkwijk: Coal tar induces AHR-dependent skin barrier repair in atopic dermatitis. in The Journal of clinical investigation 2013
Show all 2 references for ABIN1344642
Identified structural features of AHR1beta associated with low TCDD sensitivity. Substitution of the entire ligand binding domain with the corresponding sequence from mouse AHR(b-1) dramatically increased TCDD responsiveness in transactivation assays.
Transient AHR activation and cytochrome P450 1A (CYP1A) induction in livers occurred during ANIT-induced hepatobiliary impairment in medaka.
AHR plays an important role in development of cells with cancer stem cell-like qualities and that environmental AHR ligands may exacerbate breast cancer by enhancing expression of these properties.
Results determined that constitutive AhR expression coupled to BRCA-1 promoter CpG hypermethylation may be predictive markers of ERalpha (show ESR1 Proteins)-negative breast tumor development.
Lack of association between the aryl hydrocarbon receptor rs2066853 polymorphism and breast cancer
Report NcoA2 (show NCOA2 Proteins)-regulation of the AhR-ARNT (show ARNT Proteins)-HIF-1a (show HIF1A Proteins) interaction.
These results suggest that ARPE-19 cells possess an AHR-mediated transcription pathway with different target gene specificity, and that BRG1 (show SMARCA4 Proteins) is required for AHR-mediated transcription in ARPE-19 cells.
AHR promoter variant modulates its transcription and downstream effectors by allele-specific AHR-SP1 (show PSG1 Proteins) interaction functioning as a genetic marker for vitiligo (show MITF Proteins)
Control of lymphocyte homeostasis and effector function by the aryl hydrocarbon receptor
Proliferation of breast cancer cells is dependent on the expression of both LAT1 (show LAT Proteins) and AHR.
Ligand specificity and selection may be determined not only by the PAS (show PASK Proteins)-B domain, but also by AhR other parts and its protein interacting partners. Ligand binding pocket and access channels leading to it discriminate endogenous molecules and xenobiotics.
Polymorphisms of AhR Arg554Lys is not associated with endometriosis, while the AhRR (show CYP1A1 Proteins) Pro185Ala polymorphism may be associated with endometriosis risk in Asians.
AHR mRNA expression in follicular, theca, and granulosa cells suggest the involvement of AHR in the modulation of reproductive processes in the porcine ovary.
Developmental AHR activation by pollutants, and other exogenous ligands, increases the likelihood that Gnaq knockout mice will develop autoimmune diseases later in life.
AhR and NF-kappaB/Rel protein binding profile within the 3'IghRR mediates the inhibitory effects of TCDD on Ig expression and therefore antibody levels.
AhR is a negative regulator of profibrotic signals in the gut (show GUSB Proteins).
Data (including data from studies in knockout/mutant mice) suggest expression of Ahr and its translocation into nucleus are necessary for Ahr ligand-mediated synergistic induction of Ccl20 (show CCL20 Proteins) [chemokine (C-C motif) ligand 20 (show CCL20 Proteins)]; here, TCDD is Ahr ligand.
AHR plays protective roles against high-fat diet-induced hepatic steatosis and the subsequent lipotoxicity via direct transcriptional regulation of Socs3 (show SOCS3 Proteins) gene expression.
This study thus indicates a critical role of TCDD-induced AhR activation in the regulation of non-eosinophilic airway inflammation
findings reported here underscore the conclusion that AHR signaling in the developing heart is one potential target of environmental factors associated with cardiovascular disease
Suggest that endogenous AhR ligands are involved in the normal regulation of Th2-mediated immunity in the lung via a dendritic cell-dependent mechanism.
these data suggest a role for AhR in HSC (show FUT1 Proteins) functional regulation, and identify novel HSC (show FUT1 Proteins) AhR target genes that may contribute to the phenotypes observed in AhR-KO mice.
The Ahr/microRNA-212/132 axis in T cells regulates IL-10 (show IL10 Proteins) production to maintain intestinal homeostasis.
This gene encodes a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Its ligands included a variety of aromatic hydrocarbons.
aryl hydrocarbon receptor
, aryl hydrocarbon receptor 1
, aryl hydrocarbon receptor-like
, ah receptor
, aromatic hydrocarbon receptor
, class E basic helix-loop-helix protein 76
, Ah receptor
, dioxin receptor