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The protein encoded by AIP is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. Additionally we are shipping AIP Kits (18) and AIP Proteins (11) and many more products for this protein.
Showing 10 out of 103 products:
Human Monoclonal AIP Primary Antibody for ChIP, FACS - ABIN151058
Petrulis, Hord, Perdew: Subcellular localization of the aryl hydrocarbon receptor is modulated by the immunophilin homolog hepatitis B virus X-associated protein 2. in The Journal of biological chemistry 2000
Show all 23 Pubmed References
Human Polyclonal AIP Primary Antibody for ELISA, WB - ABIN253295
Vierimaa, Georgitsi, Lehtonen, Vahteristo, Kokko, Raitila, Tuppurainen, Ebeling, Salmela, Paschke, Gündogdu, De Menis, Mäkinen, Launonen, Karhu, Aaltonen: Pituitary adenoma predisposition caused by germline mutations in the AIP gene. in Science (New York, N.Y.) 2006
the well-known interaction between AIP and 2 different isoforms of phosphodiesterases (PDEs), PDE2A3 and PDE4A5, is of particular interest. While the interaction with over-expressed AIP does not seem to affect PDE2A3 function, the reported effect on PDE4A5 is, in contrast, reduced enzymatic activity.
The c.805_825dup allele in AIP, originating from a common ancestor, associates with a severe clinical phenotype of gigantism.
The prevalence of AIP mutations in young Mexican patients with acromegaly is similar to that of European cohorts.
Case Report: truncating AIP mutation, p.W279*, in father/daughter presenting with familial isolated pituitary adenoma.
A modest relationship was found between PPARalpha (show PPARA Antibodies) and AIP expression, both being significantly higher in the presence of pre-operative somatostatin (show SST Antibodies) analogues in somatotropinoma patients.
The prevalence of AIP(mut (show MUT Antibodies)) in Turkish patients was found to be 1 % in sporadic acromegaly in the present study.
No digenism with AIP was identified among patients with sporadic pituitary adenomas.
The aim of this study was to examine mutations in the aryl hydrocarbon receptor-interacting protein (AIP) gene
AIP mutations are associated with pituitary gigantism.
in a family of a patient with gigantism, identified a new AIP germline mutation (c.685C>T, p.Q229X) predicted to produce a truncated AIP protein, lacking its biological properties due to the disruption of the C-terminus binding sites for both the chaperones and the client proteins of AIP
Results demonstrated that Aip inactivation promoted somatotroph tumorigenesis and overproduction of growth hormone (show GH1 Antibodies) probably through increased Stat3 (show STAT3 Antibodies) activation.
Results provide novel evidence that AIP has an important role in the regulation of cAMP synthesis.
XAP2 exerts a negative effect on ERalpha (show ESR1 Antibodies) transcriptional activity and may thus prevent ERalpha (show ESR1 Antibodies)-dependent events.
Developmental control of apoptosis by the immunophilin (show FKBP1A Antibodies) aryl hydrocarbon receptor-interacting protein (AIP) involves mitochondrial import of the survivin (show BIRC5 Antibodies) protein
Mice with inactivation of aryl hydrocarbon receptor-interacting protein display complete penetrance of pituitary adenomas with aberrant ARNT (show ARNT Antibodies) expression.
Data show that AIP is not required for the induction of the Cyp1a1 (show CYP1A1 Antibodies) and Cyp1a2 (show CYP1A1 Antibodies) genes.
XAP2 hinders importin beta (show KPNB1 Antibodies) binding to the mAhR complex and represses the transactivation potential of the AhR (show AHR Antibodies) by stabilizing the receptor complex and/or blocking nucleocytoplasmic shuttling of the AhR (show AHR Antibodies) complex
PPARalpha (show PPARA Antibodies) is in a complex with hsp90 (show HSP90 Antibodies) and XAP2, and XAP2 appears to function as a repressor
XAP2 has a role in stabilization of the dioxin receptor (show AHR Antibodies)
The role of Xap2 and C-terminal hsp-70 (show HSP70 Antibodies) interacting protein on the endogenous Ah receptors expressed in mouse cell lines was determined.
The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus.
aryl hydrocarbon receptor interacting protein
, AH receptor-interacting protein-like
, AH receptor-interacting protein
, HBV X-associated protein 2
, immunophilin homolog ARA9
, aryl-hydrocarbon receptor-interacting protein
, HBV-X associated protein
, immunophilin XAP2