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Aryl Hydrocarbon Receptor Nuclear Translocator 2 Proteins (ARNT2)

ARNT2 encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. Additionally we are shipping ARNT2 Antibodies (56) and ARNT2 Kits (29) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ARNT2 11864 Q61324
ARNT2 25243 Q78E60
ARNT2 9915 Q9HBZ2
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Top ARNT2 Proteins at antibodies-online.com

Showing 5 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$4,077.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ARNT2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus)

Human , ,
,

More Proteins for Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2) Interaction Partners

Mouse (Murine) Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2) interaction partners

  1. data suggest that ARNT2/HIF-2beta is required at high levels during nephrogenesis in distal tubules and later exclusively in thick ascending limb

  2. The differential binding of AhR (show AHR Proteins) by Arnt (show ARNT Proteins) and Arnt2 can be ascribed to a single His/Pro amino acid difference in the PASB region of Arnt (show ARNT Proteins) and Arnt2.

  3. Cap-analysis of gene expression (CAGE) data points to Arnt2 as a key regulator in hippocampus.

Zebrafish Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2) interaction partners

  1. Arnt2 contributes to control of lateral positioning of longitudinal hypothalamic-spinal axons by negative regulation of robo3a (show ROBO3 Proteins).1 expression, which in turn attenuates the repulsive activity of Robo2 (show ROBO2 Proteins).

  2. Zebrafish gene (zfARNT2) is not essential for mediating TCDD developmental toxicity in zebrafish.

  3. The only effect in arnt2(-/-) larvae that occurred before 120 hours postfertilization (hpf) was a decrease in expression of sim1, an Arnt2 dimerization partner, in the hypothalamus and ventral thalamus at 72 hpf.

Human Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2) interaction partners

  1. Attenuated ARNT2 expression in HCC827 cells greatly promoted tumor growth.

  2. nominal associations were found between autism spectrum disorder scores and single-nucleotide polymorphisms in OXT, ARNT2 and CD38

  3. Data suggest that selected human SIM1 (single-minded homolog 1 (show SIM1 Proteins)) variants exhibit poor dimerization with ARNT2 and anomalous intracellular localization; these data were used to predict 'hot-spot' in SIM1 (show SIM1 Proteins)/SIM2 (show SIM2 Proteins) (residues 290-326) critical for function.

  4. These results provide insight into the mechanisms of NPAS4 (show NPAS4 Proteins)/ARNT (show ARNT Proteins) dimerisation and transcriptional activation.

  5. mutation of ARNT2 results in absence of detectable levels of ARNT2 transcript and protein from patient fibroblasts compared with controls, consistent with nonsense-mediated decay of the mutant transcript and loss of ARNT2 function.

  6. In white males, rs4072568 in ARNT2 was also associated with BMI (P = 9 x 10(-4)) and % body fat (P = 0.001).

  7. ARNT2 might play an important role in the modulation of HIF-1 (show HIF1A Proteins)-regulated signaling and metabolism.

  8. promotes differentiation of IL-22 (show IL22 Proteins)-producing CD4 (show CD4 Proteins)(+) T-cells

  9. There is no association of ARNT2 gene with cleft palate only (n = 45) and cleft lip/palate (n = 37).

  10. We thus propose that NDN (show NDN Proteins) regulates neuronal function and hypoxic response by regulating the activities of the ARNT2:SIM1 (show SIM1 Proteins) and ARNT2:HIF1alpha (show HIF1A Proteins) dimers, respectively.

ARNT2 Protein Profile

Protein Summary

This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting addition roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively.

Gene names and symbols associated with ARNT2

  • aryl-hydrocarbon receptor nuclear translocator 2 (ARNT2)
  • aryl hydrocarbon receptor nuclear translocator 2 (arnt2)
  • aryl hydrocarbon receptor nuclear translocator 2 (arnt.2)
  • aryl-hydrocarbon receptor nuclear translocator 2 (arnt2)
  • aryl hydrocarbon receptor nuclear translocator 2 (Arnt2)
  • aryl-hydrocarbon receptor nuclear translocator 2 (Arnt2)
  • Arnt protein
  • arnt.2 protein
  • ARNT2 protein
  • arnt2a protein
  • arnt2X protein
  • bHLHe1 protein
  • chunp6921 protein
  • Hif-2b protein
  • MGC53123 protein
  • MGC68805 protein
  • mKIAA0307 protein
  • zfARNT2 protein
  • zfARNT2a protein
  • zfARNT2b protein
  • zfARNT2c protein

Protein level used designations for ARNT2

aryl hydrocarbon receptor nuclear translocator 2 , aryl-hydrocarbon receptor nuclear translocator 2 , aryl hydrocarbon receptor nuclear translocator 2-like , ARNT protein 2 , Ah receptor nuclear translocator , unm t30256 , unm_t30256 , class E basic helix-loop-helix protein 1

GENE ID SPECIES
100067423 Equus caballus
380232 Xenopus laevis
399025 Xenopus laevis
453583 Pan troglodytes
712786 Macaca mulatta
100013571 Monodelphis domestica
100101693 Xenopus (Silurana) tropicalis
100135448 Ovis aries
100407922 Callithrix jacchus
100468247 Ailuropoda melanoleuca
11864 Mus musculus
25243 Rattus norvegicus
64277 Danio rerio
9915 Homo sapiens
415481 Gallus gallus
608366 Canis lupus familiaris
100157219 Sus scrofa
533445 Bos taurus
100727525 Cavia porcellus
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