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anti-Ash2 (Absent, Small, Or Homeotic)-Like (Drosophila) (ASH2L) Antibodies

Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. Additionally we are shipping ASH2L Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ASH2L 9070 Q9UBL3
ASH2L 23808 Q91X20
ASH2L 290829  
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Top anti-ASH2L Antibodies at antibodies-online.com

Showing 10 out of 64 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-ASH2L Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ASH2L Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-ASH2L Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Dog Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$253.00
Details
Human Rat Un-conjugated ICC, IF, IP, IHC, WB   100 μg Log in to see 1 to 2 Days
$466.67
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated ChIPSeq, ChIP, WB ASH2L antibody (pAb) tested by ChIP-Seq. ChIP was performed using the ChIP-IT® High Sensitivity Kit (Cat. No. 53040) with 30 ug of chromatin from undifferentiated hESC cells and 10 µl of antibody. ChIP DNA was sequenced on the Illumina HiSeq and 20 million sequence tags were mapped to identify ASH2L binding sites. The image shows binding across a region of chromosome 12. You can view the complete data set in the UCSC Genome Browser, starting at this specific location, here. ASH2L pAb tested by Western blot. ASH2L detection by Western blot. The analysis of ASH2L was performed using HeLa nuclear extract and ASH2L pAb at a 1:2,000 dilution. 200 μL Log in to see 4 to 5 Days
$497.22
Details
Human Rabbit Un-conjugated IHC (p), WB Human Testis (formalin-fixed, paraffin-embedded) stained with ASH2L antibody ABIN462194 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Placenta (formalin-fixed, paraffin-embedded) stained with ASH2L antibody ABIN462194 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$676.50
Details
Dog Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details

ASH2L Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
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Mouse (Murine) ,


Rat (Rattus) ,


Top referenced anti-ASH2L Antibodies

  1. Human Polyclonal ASH2L Primary Antibody for ChIPSeq, ChIP - ABIN3434035 : Cao, Chen, Cierpicki, Liu, Basrur, Lei, Dou: An Ash2L/RbBP5 heterodimer stimulates the MLL1 methyltransferase activity through coordinated substrate interactions with the MLL1 SET domain. in PLoS ONE 2010 (PubMed)
    Show all 2 references for ABIN3434035

  2. Human Polyclonal ASH2L Primary Antibody for WB - ABIN871691 : Wysocka, Myers, Laherty, Eisenman, Herr: Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1. in Genes & development 2003 (PubMed)
    Show all 2 references for ABIN871691

  3. Chicken Polyclonal ASH2L Primary Antibody for IHC, WB - ABIN2778325 : Lüscher-Firzlaff, Gawlista, Vervoorts, Kapelle, Braunschweig, Walsemann, Rodgarkia-Schamberger, Schuchlautz, Dreschers, Kremmer, Lilischkis, Cerni, Wellmann, Lüscher: The human trithorax protein hASH2 functions as an oncoprotein. in Cancer research 2008 (PubMed)

  4. Cow (Bovine) Polyclonal ASH2L Primary Antibody for WB - ABIN2778326 : Yokoyama, Wang, Wysocka, Sanyal, Aufiero, Kitabayashi, Herr, Cleary: Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression. in Molecular and cellular biology 2004 (PubMed)

More Antibodies against ASH2L Interaction Partners

Human Ash2 (Absent, Small, Or Homeotic)-Like (Drosophila) (ASH2L) interaction partners

  1. the histone methyltransferase core enzyme ASH2L was bound at EGFR (show EGFR Antibodies) in the germinal matrix and in gliomas where levels of H3K4me3 are high, and the histone acetyltransferase P300 (show EP300 Antibodies) was bound in samples with H3K27ac enrichment

  2. Ash2L acts in concert with P53 promoter occupancy to activate RNA Polymerase II by aiding formation of a stable transcription pre-initiation complex required for its activation.

  3. ASH2L enhances ERalpha (show ESR1 Antibodies) expression as a coactivator of GATA3 (show GATA3 Antibodies) in breast cancers

  4. Non active site mutations in the MLL1 SET domain render the protein defective for H3K4 dimethylation by the MLL1 core complex, which is associated with a loss of the ability of MLL1 to interact with WRAD or with the RbBP5 (show RBBP5 Antibodies)/Ash2L heterodimer.

  5. Data indicate that MLL1 methylates Ash2L in the absence of histone H3 (show HIST3H3 Antibodies), but only when assembled within a complex with WDR5 (show WDR5 Antibodies) and RbBP5 (show RBBP5 Antibodies).

  6. H2B dependent regulation of MLL (show MLL Antibodies) family histone methylatransferases depends on the N-terminal WH motif of ASH2L.

  7. crystal structure of the C-terminal SPRY domain of human Ash2L

  8. The structure shows that Ash2L contains an atypical PHD (show PDC Antibodies) finger that does not have histone tail-binding activity.

  9. ASH2L binds DNA using a forkhead-like helix-wing-helix (HWH) domain.

  10. NF-Y acts upstream of H3K4me3 deposition by recruiting Ash2L

Mouse (Murine) Ash2 (Absent, Small, Or Homeotic)-Like (Drosophila) (ASH2L) interaction partners

  1. ASH2L enhances ERalpha (show ESR1 Antibodies) expression as a coactivator of GATA3 (show GATA3 Antibodies) in breast cancers

  2. Ash2l is essential for pluripotency and maintaining open chromatin in embryonic stem cells

  3. Tbx1 (show TBX1 Antibodies) and Ash2l have overlapping mRNA and protein expression patterns during development.

  4. Several candidate targets of complexes containing Ap2delta and Ash2l were identified that can be used to further elucidate their roles during development and showed that Fgfr3 (show FGFR3 Antibodies) is a novel direct target of these complexes.

  5. Ap2delta associates with ASH2L and MLL2 (ALR (show MLL2 Antibodies)), forming a complex that methylates lysine 4 of histone H3 (show HIST3H3 Antibodies).

ASH2L Antigen Profile

Protein Summary

Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis (By similarity).

Gene names and symbols associated with ASH2L

  • ash2 (absent, small, or homeotic)-like (ASH2L) antibody
  • ash2-like protein (ash2-like) antibody
  • hypothetical protein (ASH2-like) antibody
  • ash2-like (LOC100194676) antibody
  • ash2-like (LOC100338600) antibody
  • ash2-like (LOC100344501) antibody
  • ash2-like (LOC100348920) antibody
  • ash2 (absent, small, or homeotic)-like (ash2l) antibody
  • ash2 (absent, small, or homeotic)-like (Drosophila) (ASH2L) antibody
  • ash2 (absent, small, or homeotic)-like (Drosophila) (ash2l) antibody
  • ash2 (absent, small, or homeotic)-like (Drosophila) (Ash2l) antibody
  • ASH2 antibody
  • ash2-like antibody
  • ASH2L antibody
  • ASH2L1 antibody
  • ASH2L2 antibody
  • Bre2 antibody
  • fb34c06 antibody
  • fe38b04 antibody
  • fi20h02 antibody
  • wu:fb34c06 antibody
  • wu:fe38b04 antibody
  • wu:fi20h02 antibody
  • zgc:171444 antibody

Protein level used designations for ASH2L

ash2-like protein , hypothetical protein , ash2-like , ASH2-like protein , set1/Ash2 histone methyltransferase complex subunit ASH2

GENE ID SPECIES
699382 Macaca mulatta
778945 Ciona intestinalis
9660760 Selaginella moellendorffii
100194676 Salmo salar
100338600 Oryctolagus cuniculus
100344501 Oryctolagus cuniculus
100348920 Oryctolagus cuniculus
100127317 Xenopus laevis
9070 Homo sapiens
558193 Danio rerio
475589 Canis lupus familiaris
100138350 Bos taurus
23808 Mus musculus
290829 Rattus norvegicus
426774 Gallus gallus
Selected quality suppliers for anti-ASH2L (ASH2L) Antibodies
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