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Asp (Abnormal Spindle) Homolog, Microcephaly Associated (Drosophila) (ASPM) ELISA Kits

ASPM is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Additionally we are shipping Asp (Abnormal Spindle) Homolog, Microcephaly Associated (Drosophila) Antibodies (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ASPM 289054  
ASPM 259266 Q8IZT6
ASPM 12316 Q8CJ27
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Top Asp (Abnormal Spindle) Homolog, Microcephaly Associated (Drosophila) ELISA Kits at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 6.25 pg/ml 25-1600 pg/mL 96 Tests Log in to see 11 to 13 Days
$910.56
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Chicken
96 Tests Log in to see 16 to 21 Days
$999.43
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Mouse
96 Tests Log in to see 16 to 21 Days
$999.43
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Rat
96 Tests Log in to see 16 to 21 Days
$999.43
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More ELISA Kits for Asp (Abnormal Spindle) Homolog, Microcephaly Associated (Drosophila) Interaction Partners

Human Asp (Abnormal Spindle) Homolog, Microcephaly Associated (Drosophila) (ASPM) interaction partners

  1. Suberoylanilide hydroxamic acid enhanced the expression of malignant genes such as ASPM in lung cancer cells remaining after treatment, creating a more drug-resistant state.

  2. Gene-level tests showed that DRD2 (show DRD2 ELISA Kits) was associated with vocabulary, ASPM with vocabulary and reading decoding, and AVPR1A (show AVPR1A ELISA Kits) with all three endophenotypes.

  3. ASPM mutations in primary autosomal recessive microcephaly patients in ethnically diverse patients

  4. microcephalin (show MCPH1 ELISA Kits) and ASPM expression are deregulated in epithelial ovarian cancer progression

  5. ASPM promotes aggressiveness of pancreatic ductal adenocarcinoma (PDAC) by maintaining Wnt (show WNT2 ELISA Kits)-beta-catenin (show CTNNB1 ELISA Kits) signaling and stem cell features of PDAC cells.

  6. Identification of a novel ASPM mutation in a family with primary microcephaly.

  7. Data indicate frameshift and stop mutation leading to truncations (c.3796G > T, p.E1266X and c.7815_7816del, p.E2605fs) in the ASPM gene unexpectedly found on chromosome 1 in apparent X-linked microcephalic intellectual deficit patients.

  8. the association between the recently derived allele of ASPM is likely to be specific and is tied to higher level brain functions in the temporal cortex related to human communication.

  9. Results show for the first time that ASPM is required for efficient non-homologous end-joining in mammalian cells.

  10. We conclude that the common variations we measured in the 4 microcephaly genes, ASPM, MCPH1 (show MCPH1 ELISA Kits), CDK5RAP2 (show CDK5RAP2 ELISA Kits), and CENPJ (show CENPJ ELISA Kits), do not affect the risk of Alzheimer disease

Mouse (Murine) Asp (Abnormal Spindle) Homolog, Microcephaly Associated (Drosophila) (ASPM) interaction partners

  1. Interaction between ASPM and the Cdk2 (show CDK2 ELISA Kits)/Cyclin E (show CCNE1 ELISA Kits) complex regulated the Cyclin (show PCNA ELISA Kits) activity by modulating its ubiquitination and localization into the nucleus.

  2. Aspm, a gene that is mutated in familial microcephaly, regulates postnatal neurogenesis in the cerebellum and supports the growth of medulloblastoma, the most common malignant pediatric brain tumor.

  3. Aspm is essential to the proliferation and differentiation of neural stem/progenitor cells. The Aspm gene loss model provided a novel pathogenetic insight into acquired microcephaly, which can be caused by in utero exposure teratogens.

  4. ASPM plays a critical role in meiotic spindle assembly and meiotic progression in mouse oocytes.

  5. AspM is expressed by proliferating cells of the adult mouse SVZ that can generate neuroblasts fated to become olfactory bulb neurons

  6. knockdown of Aspm results in decreased Wnt (show WNT2 ELISA Kits)-mediated transcription

  7. truncated Aspm proteins cause a massive loss of germ cells, resulting in a severe reduction in testis and ovary size accompanied by reduced fertility

  8. tissue distribution of Calmbp1 in fetal and adult mice

  9. evolutionary selection of specific segments of the ASPM sequence strongly relates to differences in cerebral cortical size

  10. Aspm is crucial for maintaining a cleavage plane orientation that allows symmetric, proliferative divisions of neuroepithelial cells during brain develo

Asp (Abnormal Spindle) Homolog, Microcephaly Associated (Drosophila) (ASPM) Antigen Profile

Antigen Summary

This gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ASPM

  • asp (abnormal spindle) homolog, microcephaly associated (Drosophila) (Aspm) antibody
  • asp (abnormal spindle) homolog, microcephaly associated (Drosophila) (ASPM) antibody
  • asp (abnormal spindle) homolog, microcephaly associated (Drosophila) (LOC100232605) antibody
  • asp (abnormal spindle) homolog, microcephaly associated (aspm) antibody
  • asp (abnormal spindle)-like, microcephaly associated (Drosophila) (Aspm) antibody
  • ASP antibody
  • ASPM antibody
  • Calmbp1 antibody
  • D330028K02Rik antibody
  • MCPH5 antibody
  • Sha1 antibody

Protein level used designations for ASPM

asp (abnormal spindle) homolog, microcephaly associated , calmodulin binding protein 1 , asp (abnormal spindle)-like, microcephaly associated , asp (abnormal spindle) homolog, microcephaly associated (Drosophila) , Abnormal spindle-like microcephaly-associated protein homolog , abnormal spindle-like microcephaly-associated protein , abnormal spindle-like microcephaly-associated protein homolog , abnormal spindle-like microcephaly protein , calmodulin-binding protein 1 , calmodulin-binding protein Sha1 , spindle and hydroxyurea checkpoint abnormal protein

GENE ID SPECIES
289054 Rattus norvegicus
424354 Gallus gallus
449566 Pan troglodytes
100232605 Taeniopygia guttata
100379990 Xenopus (Silurana) tropicalis
259266 Homo sapiens
534849 Bos taurus
493695 Felis catus
443284 Ovis aries
480009 Canis lupus familiaris
711153 Macaca mulatta
12316 Mus musculus
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