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Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (S. Cerevisiae) Proteins (ALG2)

ALG2 encodes a member of the glycosyltransferase 1 family. Additionally we are shipping ALG2 Antibodies (54) and ALG2 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ALG2 85365 Q9H553
Rat ALG2 ALG2 313231  
ALG2 56737 Q9DBE8
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Top ALG2 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ALG2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (S. Cerevisiae) (ALG2) Interaction Partners

Human Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (S. Cerevisiae) (ALG2) interaction partners

  1. Lack of ALG-2 (show PDCD6 Proteins), ALIX (show PDCD6IP Proteins) or Vps4B (show vps4b Proteins) each prevents shedding, and repair of the injured cell membrane

  2. Results show the crystal structure of the complex between ALG-2 (show PDCD6 Proteins) and a peptide of Sec31A (show SEC31A Proteins) and found that the peptide binds to the third hydrophobic pocket (Pocket 3) and that ALG-2 (show PDCD6 Proteins) recognizing 2 types of motifs at different hydrophobic surfaces of Sec31A (show SEC31A Proteins).

  3. ALG-2/Sec31A interactions were not required for the localization of Sec31A to ER exit sites per se but appeared to acutely regulate the stability and trafficking of the cargo receptor p24 and the distribution of the vesicle tether protein p115

  4. ALG-2 (show PDCD6 Proteins) attenuates COPII budding in vitro and stabilizes the Sec23/Sec31A (show SEC31A Proteins) complex.

  5. The results of in vitro binding assays using purified recombinant proteins indicated that ALG-2 (show PDCD6 Proteins) functions as a Ca(2 (show CA2 Proteins))-dependent adaptor protein that bridges ALIX (show PDCD6IP Proteins) and ESCRT-I (show VPS28 Proteins) to form a ternary complex

  6. This is the first report showing interaction of ALG-2 (show PDCD6 Proteins) with a P-body component (PATL1 (show PATL1 Proteins)).PATL1 (show PATL1 Proteins) as well as DCP1A (show DCP1A Proteins), a well-known P-body marker, co-localized with a subset of ALG-2 (show PDCD6 Proteins).

  7. We identify ALG14 (show ALG14 Proteins) and ALG2 (show PDCD6 Proteins) as novel genes in which mutations cause a congenital myasthenic syndrome

  8. the alg2 (show PDCD6 Proteins) binding site is one of the key determinants of the retention kinetics of Sec31A (show SEC31A Proteins) at endoplasmic reticulum exit sites

  9. found that targeting Requiem and Alg-2 (show PDCD6 Proteins) did not result in extended culture viability, but resulted in an increase in maximum viable cell numbers and cumulative IVCD under fed-batch conditions

  10. inability of the two-residue shorter ALG-2 (show PDCD6 Proteins) isoform to bind Alix (show PDCD6IP Proteins)

Mouse (Murine) Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (S. Cerevisiae) (ALG2) interaction partners

  1. the observation that both ALG-2 (show PDCD6 Proteins) isoforms bind Mg2 (show MCOLN1 Proteins)+ with high affinity is the most significant finding of this study

  2. Thus, Alg2, as a downstream mediator of Hivep3, suppresses osteogenesis, whereas it promotes chondrogenesis.

  3. ALG-2 (show PDCD6 Proteins) binding to Scotin (show SHISA5 Proteins) is strictly calcium dependent, indicating a role of this interaction in calcium signaling pathways

ALG2 Protein Profile

Protein Summary

This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii). Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with ALG2

  • ALG2, alpha-1,3/1,6-mannosyltransferase (alg2)
  • ALG2, alpha-1,3/1,6-mannosyltransferase (ALG2)
  • ALG2, alpha-1,3/1,6-mannosyltransferase (Alg2)
  • asparagine-linked glycosylation 2 (alpha-1,3-mannosyltransferase) (Alg2)
  • asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae) (ALG2)
  • similar to endoplasmic reticulum mannosyltransferase (ALG2)
  • 1110018A23Rik protein
  • 1300013N08Rik protein
  • ALPG2 protein
  • CDGIi protein
  • hALPG2 protein
  • MNCb-5081 protein
  • NET38 protein

Protein level used designations for ALG2

asparagine-linked glycosylation 2 homolog (yeast, alpha-1,3-mannosyltransferase) , GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase , GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase , GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase , alpha-1,3-mannosyltransferase ALG2 , alpha-1,3/1,6-mannosyltransferase ALG2 , asparagine-linked glycosylation 2 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase) , asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog , asparagine-linked glycosylation protein 2 homolog , homolog of yeast ALG2 , hypothetical protein

GENE ID SPECIES
446622 Xenopus laevis
85365 Homo sapiens
313231 Rattus norvegicus
56737 Mus musculus
474780 Canis lupus familiaris
100113423 Sus scrofa
538899 Bos taurus
3647832 Candida albicans SC5314
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