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Aspartoacylase (ASPA) ELISA Kits

ASPA encodes an enzyme that catalyzes the conversion of N-acetyl_L-aspartic acid (NAA) to aspartate and acetate. Additionally we are shipping ASPA Antibodies (73) and ASPA Proteins (14) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ASPA 443 P45381
ASPA 11484 Q8R3P0
ASPA 79251 Q9R1T5
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Top ASPA ELISA Kits at antibodies-online.com

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Chicken
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$999.43
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$875.60
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Rat
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Mouse
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Cow
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More ELISA Kits for ASPA Interaction Partners

Human Aspartoacylase (ASPA) interaction partners

  1. report of 2 Egyptian sibling patients suspected of Canavan disease (CD); study revealed homozygosity for substitution T530C (Ile177Thr) in exon 4 of the ASPA gene in both sibs; substitution T530C (Ile177Thr) results in a novel missense mutation causing a CD phenotype with severe clinical characteristics

  2. Four ASPA missense mutations associated with Canavan disease are structurally characterized.

  3. Definitive evidence is presented to show that the recombinantly-expressed human aspartoacylase is not a glycoprotein.

  4. This is the first case report of ASPA mutation studies in Canavan disease from Indian subcontinent.

  5. a novel mutation Y88X within the aspartoacylase gene in a consanguineous family with an affected child diagnosed as Canavan disease.

  6. Human aspartoacylase gene expression was high not only in brain and kidney, but also in lung and liver.

  7. Gene ASPA (NM_000049) was undertaken to sequence for mutation analysis.

  8. We report on an Italian female patient with Canavan disease due to a missense mutation of the aspartoacylase gene and a 17p13.3 chromosomal microdeletion

  9. the ASPA gene was analysed in 22 unrelated non-Jewish patients with Canavan disease, and 24 different mutations were found

  10. Mild-onset presentation of Canavan's disease associated with novel G212A point mutation in aspartoacylase gene

Mouse (Murine) Aspartoacylase (ASPA) interaction partners

  1. Gata6 (show GATA6 ELISA Kits) regulates differentiation, metabolism, and survival of resident peritoneal macrophages through aspartoacylase.

  2. aspartoacylase is proposed here to support lipid synthesis and energy metabolism via the provision of substrate for both cellular processes during early postnatal development

  3. Intracellular vacuolisation in astrocytes coincides with axonal swellings in cerebellum and brain stem of aspa(lacZ/lacZ (show GLB1 ELISA Kits)) mutants indicating that astroglia may act as an osmolyte buffer in the aspa-deficient CNS

  4. Aspa defects were associated with increased levels of acetylated histone H3 (show HIST3H3 ELISA Kits), decreased chromatin compaction and increased GFAP (show GFAP ELISA Kits) protein, a marker for astrogliosis. Early in postnatal development ASPA defic affects oligodendrocyte maturation and myelination

  5. Death of OLs, neurons, and astrocytes was identified in every region of the aspartoacylase KO brain. These findings support involvement of ASPA in CNS development and function.

  6. ASPA gene defect in the mouse leads to spinal cord pathology; these changes may be involved in the cause of the physiological/behavioral abnormalities seen in the knockout mouse.

  7. normal hydrolysis of N-acetylaspartic acid is affected by aspartoacylase activity seen in the type 2 diabetes model mouse

  8. we now present immunoblot, proteomic, and biochemical evidence that the membrane-bound form of ASPA is intrinsic to purified myelin membranes.

  9. Nur7( Q193X) is a nonsense mutation in the mouse aspartoacylase gene that causes spongy degeneration of the CNS.

ASPA Antigen Profile

Antigen Summary

This gene encodes an enzyme that catalyzes the conversion of N-acetyl_L-aspartic acid (NAA) to aspartate and acetate. NAA is abundant in the brain where hydrolysis by aspartoacylase is thought to help maintain white matter. This protein is an NAA scavenger in other tissues. Mutations in this gene cause Canavan disease. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with Aspartoacylase (ASPA) ELISA Kits

  • aspartoacylase (ASPA) antibody
  • aspartoacylase (aspa) antibody
  • Aspartoacylase (Fbal_2465) antibody
  • aspartoacylase (Aspa) antibody
  • Acy-2 antibody
  • Acy2 antibody
  • ASP antibody
  • nur7 antibody
  • zgc:171507 antibody

Protein level used designations for Aspartoacylase (ASPA) ELISA Kits

aspartoacylase (Canavan disease) , Aminoacylase-2 , aspartoacylase (aminoacylase 2, Canavan disease) , Aspartoacylase , ACY-2 , aminoacylase 2 , aminoacylase-2 , aspartoacylase (aminoacylase) 2

GENE ID SPECIES
454430 Pan troglodytes
706170 Macaca mulatta
733935 Xenopus (Silurana) tropicalis
9771274 Ferrimonas balearica DSM 9799
509432 Bos taurus
100142661 Sus scrofa
443 Homo sapiens
100173374 Pongo abelii
11484 Mus musculus
79251 Rattus norvegicus
557232 Danio rerio
Selected quality suppliers for ASPA (ASPA) ELISA Kits
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