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Aspartyl-tRNA synthetase (DARS) is part of a multienzyme complex of aminoacyl-tRNA synthetases. Additionally we are shipping DARS Antibodies (42) and DARS Proteins (9) and many more products for this protein.
Genetic variants of the DARS gene may influence individual susceptibility to isolated VSD in Chinese Han population. Risk of VSD was significantly associated with rs2164331 [G/A; odds ratio (OR) = 0.78, 95% confidence interval (CI) = 0.69-0.91; P = 3.17 x 10(-3)], rs6738266 [G/A; OR = 1.17, 95% CI = 1.05-1.29, P = 1.83 x 10(-3)], and rs309143 [G/A; OR = 1.09, 95% CI = 1.01-1.17; P = 3.12 x 10(-2)].
Report on the crystal structure of human cytosolic aspartyl-tRNA synthetase (DRS) at a resolution of 2.25 A.
Mutations in DARS cause hypomyelination with brain stem and spinal cord involvement and leg spasticity.
the N-terminus shows a less-ordered structure with flexible beta-turn, suggesting that when tRNA is stretched, the dissociation rate of Asp (show ASIP ELISA Kits)-tRNA from aspartyl-tRNA synthetase is reduced, giving time for elongation factor (show TSFM ELISA Kits) 1alpha to interact with Asp (show ASIP ELISA Kits)-tRNA.
Aspartyl-tRNA synthetase (DARS) is part of a multienzyme complex of aminoacyl-tRNA synthetases. Aspartyl-tRNA synthetase charges its cognate tRNA with aspartate during protein biosynthesis.
, aspartyl-tRNA synthetase, cytoplasmic
, Aspartyl-tRNA synthetase
, aspartyl-tRNA synthetase, cytoplasmic-like
, aspartate tRNA ligase 1, cytoplasmic
, aspartate--tRNA ligase, cytoplasmic
, cell proliferation-inducing gene 40 protein
, cell proliferation-inducing protein 40
, Aspartyl-tRNA synthetase, cytoplasmic