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Ataxin 1 Proteins

(Ataxin 1 (ATXN1))
The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. The function of the ataxins is not known. This locus has been mapped to chromosome 6, and it has been determined that the diseased allele contains 41-81 CAG repeats, compared to 6-39 in the normal allele, and is associated with spinocerebellar ataxia type 1 (SCA1). At least two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2010].
Ataxin 1 Protein (ATXN1) (AA 576-675) (GST tag) Ataxin 1 Protein (ATXN1) (AA 576-675) (GST tag) Ataxin 1 Protein (ATXN1) (AA 576-675) (GST tag) (ABIN1346189)

ATXN1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

Ataxin 1 Protein (ATXN1) (AA 1-815) (His tag) Ataxin 1 Protein (ATXN1) (AA 1-815) (His tag) Ataxin 1 Protein (ATXN1) (AA 1-815) (His tag) (ABIN3089722)

Crystallography grade ATXN1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

Ataxin 1 Protein (ATXN1) (AA 1-791) (His tag) Ataxin 1 Protein (ATXN1) (AA 1-791) (His tag) Ataxin 1 Protein (ATXN1) (AA 1-791) (His tag) (ABIN3119805)

Crystallography grade ATXN1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

Ataxin 1 Proteins by Grade

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Ataxin 1 Proteins by Origin

Find Ataxin 1 Proteins for a variety of species such as anti-Human Ataxin 1, anti-Mouse Ataxin 1. The species listed below are among those available. Click on a link to go to the corresponding products.

Ataxin 1 Proteins by Source

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Ataxin 1 Proteins by Protein Type

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Ataxin 1 Proteins by Application

Find Ataxin 1 Proteins validated for a specific application such as WB, SDS, ELISA, AbP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Ataxin 1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1346189
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3089722
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3119805
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7390679
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7415551
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2715013
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2715012
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our Ataxin 1 Proteins

Yoon, Abdelmohsen, Kim, Yang, Martindale, Tominaga-Yamanaka, White, Orjalo, Rinn, Kreft, Wilson, Gorospe: "Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination." in: Nature communications, Vol. 4, pp. 2939, (2013) (PubMed).

Aliases for Ataxin 1 Proteins

ataxin 1 (ATXN1) Proteins
ataxin 1b (atxn1b) Proteins
ataxin 1 (Atxn1) Proteins
Ataxin 1 (Atx-1) Proteins
2900016G23Rik Proteins
ataxin 1b Proteins
ATX1 Proteins
Atx1 Proteins
ATXN1 Proteins
atxn1 Proteins
C85907 Proteins
CG4547 Proteins
D6S504E Proteins
dAtx-1 Proteins
dAtx1 Proteins
Dmel\\CG4547 Proteins
ENSMUSG00000074917 Proteins
Gm10786 Proteins
SCA1 Proteins
Sca1 Proteins
sca1 Proteins
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