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Ataxin 7-Like 3 Proteins (ATXN7L3)

Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Additionally we are shipping ATXN7L3 Antibodies (7) and ATXN7L3 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ATXN7L3 56970 Q14CW9
ATXN7L3 217218 A2AWT3
ATXN7L3    
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Top ATXN7L3 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$3,004.83
Details

ATXN7L3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human

Mouse (Murine)

Zebrafish (Danio rerio)

More Proteins for Ataxin 7-Like 3 (ATXN7L3) Interaction Partners

Human Ataxin 7-Like 3 (ATXN7L3) interaction partners

  1. Downregulation of ATXN7L3 by short hairpin RNA speci fi cally inactivated the SAGA deubiquitination activity, leading to a strong increase of global H2B ubiquitination and a moderate increase of H2A ubiquitination.

  2. The solution structures of the SCA7 domain of both ATXN7 and ATXN7L3 reveal a new, common zinc-finger motif at the heart of two distinct folds, providing a molecular basis for the observed functional differences.

  3. ATXN7L3, USP22, & ENY2 are required cofactors for full transcriptional activity by nuclear receptors. The deubiquitinase activity of TFTC/STAGA HAT counteracts heterochromatin silencing & is a positive cofactor for in vivo nuclear receptor activation.

ATXN7L3 Protein Profile

Protein Summary

Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription (By similarity).

Gene names and symbols associated with Ataxin 7-Like 3 Proteins (ATXN7L3)

  • ataxin 7-like 3 (ATXN7L3)
  • ataxin 7-like 3 (Atxn7l3)
  • ataxin 7-like 3 (atxn7l3)
  • E030022H21Rik protein
  • si:busm1-180g5.4 protein
  • si:dz180g5.4 protein
  • wu:fj12f07 protein
  • zgc:136438 protein
  • zgc:158566 protein

Protein level used designations for Ataxin 7-Like 3 Proteins (ATXN7L3)

SAGA-associated factor 11 homolog , ataxin-7-like protein 3

GENE ID SPECIES
56970 Homo sapiens
217218 Mus musculus
368510 Danio rerio
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