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GTPase tethering membranes through formation of trans- homooligomer and mediating homotypic fusion of endoplasmic reticulum membranes. Additionally we are shipping ATL3 Proteins (7) and ATL3 Kits (1) and many more products for this protein.
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Hamster Polyclonal ATL3 Primary Antibody for WB - ABIN650914
Hu, Shibata, Zhu, Voss, Rismanchi, Prinz, Rapoport, Blackstone: A class of dynamin-like GTPases involved in the generation of the tubular ER network. in Cell 2009
Show all 2 references for 650914
These results suggest that the three ATLs have different capacities to mediate endoplasmic reticulum fusion, with ATL1 (show ATL1 Antibodies) being the strongest and ATL3 being the weakest.
ATL3 is implicated in the structural organization of intracellular organelles, which may be critical to axonal survival.
A family of human GTPases, atlastin-2 (show ATL2 Antibodies) and -3 that are closely related to atlastin-1 (show ATL1 Antibodies) are described.
Endoplasmic reticulum morphology is markedly disrupted in ATL1 (show ATL1 Antibodies), ATL2 (show ATL2 Antibodies), and ATL3 knockout cells.
GTPase tethering membranes through formation of trans- homooligomer and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis (By similarity).
atlastin GTPase 3
, atlastin 3