Atonal Homolog 7 (Drosophila) (ATOH7) ELISA Kits

This intronless gene encodes a member of the basic helix-loop-helix family of transcription factors, with similarity to Drosophila atonal gene that controls photoreceptor development. Additionally we are shipping ATOH7 Antibodies (66) and ATOH7 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat ATOH7 ATOH7 365564  
Anti-Mouse ATOH7 ATOH7 53404 Q9Z2E5
Anti-Human ATOH7 ATOH7 220202 Q8N100
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More ELISA Kits for ATOH7 Interaction Partners

Zebrafish Atonal Homolog 7 (Drosophila) (ATOH7) interaction partners

  1. Atoh7 indirectly impacts amacrine-cell division modes to regulate the right number of Barhl2 (show BARHL2 ELISA Kits)-expressing cells. Atoh7 itself influences the subtypes of Barhl2 (show BARHL2 ELISA Kits)-dependent amacrine cells.

  2. Observations suggest that Irx2 (show IRX2 ELISA Kits) functions downstream of irx1a (show IRX1 ELISA Kits) to control shh (show SHH ELISA Kits) expression in the retina. Study proposed a novel transcriptional cascade of ath5-irx1a (show IRX1 ELISA Kits)-irx2a in the regulation of hedgehog (show SHH ELISA Kits) waves during vertebrate retinal development.

  3. Staggered cell-intrinsic timing of ath5 expression underlies the wave of ganglion cell neurogenesis in the zebrafish retina.

Mouse (Murine) Atonal Homolog 7 (Drosophila) (ATOH7) interaction partners

  1. Pou4f2 (show POU4F2 ELISA Kits) and Isl1 (show ISL1 ELISA Kits), are sufficient to specify the retinal ganglion cell fate in ATOH7 deficient mice

  2. This study present evidence for a Pax6 (show PAX6 ELISA Kits)-Atoh7-Eya2 (show EYA2 ELISA Kits) pathway that acts downstream of Atoh7 but upstream of differentiation factor Pou4f2 (show POU4F2 ELISA Kits).

  3. Notch (show NOTCH1 ELISA Kits) signaling controls the overall tempo of retinogenesis through Atoh7 and Neurog2 (show NEUROG2 ELISA Kits), by integrating cell fate specification, the wave of neurogenesis and the developmental status of cells ahead of this wave

  4. The level of basic helix-loop-helix factor Math5 expression may determine the ultimate number of retinal ganglion cells.

  5. Atoh7 acts dominantly in Neurod1-expressing retina progenitor cells to activate the retinal ganglion cell genetic program.

  6. Results suggest that Math5 is not sufficient to stimulate retinal ganglion cell (RGC)fate.

  7. new insights into Math5 function, ganglion cell development, and the mechanism of retinal fate determination were provided.

  8. The present data demonstrates that the loss of ganglion cells in the Math5(-/-) mice is associated with a lack of retinal vascular development.

  9. Report Math5 expression/function in retinal ganglion cells.

  10. Data suggest that Math5 regulates the generation of multiple retinal cell types via different mechanisms during retinogenesis.

Human Atonal Homolog 7 (Drosophila) (ATOH7) interaction partners

  1. We evaluated 21 consanguineous NCRNA pedigrees and identified the causal mutations in known retinal genes in 13 out of our 21 families. We found mutations in ATOH7 in three families.

  2. We discovered a novel SNP, rs56238729 (P = 1.22 x 10-13), in the ATOH7-PBLD (show PBLD ELISA Kits) region that is significantly associated with VCDR in Latino individuals.

  3. The genotype and allele frequencies of the polymorphism in ATOH7 did not show any statistically significant association with primary open angle glaucomacompared to controls.

  4. Familial linkage studies for primary angle-closure glaucoma have been performed and identified ATOH7 causative primary angle-closure glaucoma disease

  5. Single nucleotide polymorphism in ATOH7 gene is associated with primary open angle glaucoma.

  6. The significant association of three common variants in TMCO1 (show TMCO1 ELISA Kits), ATOH7, and CAV1 (show CAV1 ELISA Kits) with primary open angle, primary angle closure, and pseudoexfoliation glaucoma was found in Pakistani cohorts.

  7. Mutations within the ATOH7 gene are not implicated in the pathogenesis of optic nerve hypoplasia in our patient cohort.

  8. This study finds that ATOH7 is associated with optic disc size but not independently with cup/disk ratio.

  9. a bHLH mutation in ATOH7 causes recessive persistent hyperplasia of the primary vitreous

  10. findings document Mendelian mutations within ATOH7 and imply a role for this molecule in the development of structures at the front as well as the back of the eye; study provides further insights into the function of ATOH7, especially its importance in retinal vascular development and hyaloid regression

ATOH7 Antigen Profile

Antigen Summary

This intronless gene encodes a member of the basic helix-loop-helix family of transcription factors, with similarity to Drosophila atonal gene that controls photoreceptor development. Studies in mice suggest that this gene plays a central role in retinal ganglion cell and optic nerve formation. Mutations in this gene are associated with nonsyndromic congenital retinal nonattachment.

Gene names and symbols associated with ATOH7

  • atonal homolog 7 (Drosophila) (Atoh7) antibody
  • atonal homolog 7 (Drosophila) (ATOH7) antibody
  • atonal homolog 7 (LOC100230256) antibody
  • atonal homolog 7 (LOC100342736) antibody
  • atonal homolog 7 (atoh7) antibody
  • ATH5 antibody
  • ATOH7 antibody
  • bHLHa13 antibody
  • Math5 antibody
  • zath5 antibody

Protein level used designations for ATOH7

atonal homolog 7 , atonal homolog 7 (Drosophila) , atonal homolog 5 , helix-loop-helix protein zATH-5 , lak , lakritz , protein atonal homolog 5 , protein atonal homolog 7 , protein lakritz , helix-loop-helix protein mATH-5 , class A basic helix-loop-helix protein 13 , helix-loop-helix protein hATH-5 , Atonal Homolog 5 , atonal transcription factor homologue , cATH5 , helix-loop-helix protein cATH-5

365564 Rattus norvegicus
466090 Pan troglodytes
489014 Canis lupus familiaris
539903 Bos taurus
100230256 Taeniopygia guttata
100342736 Oryctolagus cuniculus
58216 Danio rerio
53404 Mus musculus
220202 Homo sapiens
395388 Gallus gallus
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