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Atrophin 1 (ATN1) ELISA Kits

Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. Additionally we are shipping Atrophin 1 Antibodies (26) and Atrophin 1 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ATN1 1822 P54259
ATN1 13498 O35126
ATN1 29515 P54258
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More ELISA Kits for Atrophin 1 Interaction Partners

Human Atrophin 1 (ATN1) interaction partners

  1. Epigenetic regulation of ATN1 by LSD1 (show KDM1A ELISA Kits) is required for cortical progenitor maintenance.

  2. Juvenile myoclonic epilepsy is not associated with the DRPLA gene in a European population.

  3. These data demonstrate that the expanded trinucleotide repeat within ATN-1 mRNA is a potential target for compounds designed to achieve allele-selective inhibition of ATN-1 protein, and one agent may allow the targeting of multiple disease genes.

  4. results suggest that expanded polyQ repeats in ATN1 may contribute to neurodegeneration via alterations in both protein aggregation and intracellular localization.

  5. This study demonistrated that hypoalbuminemia in early onset DRPLA revealed the possibility of multiorgan involvement.

  6. In cerebrum and cerebellum of DRPLA transgenic mouse lines at 4, 8, and 12 weeks it is demonstrated that both the number and expression levels of the altered genes are highly dependent on CAG repeat (show CELF3 ELISA Kits) length and age in both brain regions.

  7. This study demonistrated that Atn1 is response for Dentatorubral-pallidoluysian atrophy.

  8. This sttudy suggested that age-dependent and CAG repeat (show CELF3 ELISA Kits)-dependent intranuclear accumulation of mutant DRPLA leading to nuclear dysfunctions are suggested to be the essential pathophysiologic mechanisms in Dentatorubral-pallidoluysian atrophy.

  9. Atrophin-1 promote neurodegeneration with autophagic hallmarks both in neuronal photoreceptors and glial cells.

  10. the C-terminal fragment plays a principal role in the pathological accumulation of ATN1 in dentatorubral-pallidoluysian atrophy

Mouse (Murine) Atrophin 1 (ATN1) interaction partners

  1. These results support the model that poly-Q expanded Atrophin-1 proteins cause dentatorubral-pallidoluysian atrophy in a manner independent of any functional interaction with wild-type Atrophin-1 proteins.

  2. TLX (show NR2E1 ELISA Kits) interacts with atrophin1 (Atn1), a corepressor that is involved in human neurodegenerative dentatorubral-pallidoluysian atrophy (DRPLA) and that is essential for development of multiple tissues.

  3. Atrophin-1 and the short form of Atrophin-2 (show RERE ELISA Kits) can act as potent and evolutionarily conserved transcriptional activators.

  4. Fat1 and Atrs 1,2 act in concert after vascular injury but show further that distinct Atr isoforms have disparate effects on VSMC directional migration.

Atrophin 1 (ATN1) Antigen Profile

Antigen Summary

Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-23 copies to 49-75 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.

Gene names and symbols associated with Atrophin 1 (ATN1) ELISA Kits

  • atrophin 1 (ATN1) antibody
  • atrophin 1 (Atn1) antibody
  • ATN1 antibody
  • Atr1 antibody
  • atrophin-1 antibody
  • B37 antibody
  • D12S755E antibody
  • Drpla antibody
  • HRS antibody
  • NOD antibody
  • RERE antibody

Protein level used designations for Atrophin 1 (ATN1) ELISA Kits

arginine-glutamic acid dipeptide (RE) repeats , atrophin-1 , atrophin 1 , dentatorubral-pallidoluysian atrophy protein , dentatorubral pallidoluysian atrophy , dentatorubral-pallidoluysian atrophy protein homolog

513125 Bos taurus
611608 Canis lupus familiaris
722114 Macaca mulatta
100349239 Oryctolagus cuniculus
100599977 Nomascus leucogenys
1822 Homo sapiens
13498 Mus musculus
29515 Rattus norvegicus
427946 Gallus gallus
611607 Canis lupus familiaris
451803 Pan troglodytes
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