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Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. Additionally we are shipping ATG12 Proteins (19) and ATG12 Kits (9) and many more products for this protein.
Showing 10 out of 214 products:
Human Polyclonal ATG12 Primary Antibody for IF, IHC (p) - ABIN388536
Lum, DeBerardinis, Thompson: Autophagy in metazoans: cell survival in the land of plenty. in Nature reviews. Molecular cell biology 2005
Show all 8 references for ABIN388536
Yeast (Saccharomyces cerevisiae) Polyclonal ATG12 Primary Antibody for EIA, WB - ABIN116953
Krysko, Samoylenko, Polishchuk, Andronati, Kabanova, Khristova, Kuzmin, Kabanov, Krysko, Varnek, Grygorash: RGD mimetics containing phthalimidine fragment as novel ligands of fibrinogen receptor. in Bioorganic & medicinal chemistry letters 2011
Show all 8 references for ABIN116953
Human Monoclonal ATG12 Primary Antibody for IF, IHC (p) - ABIN387794
Xia, Zhang, Chen, Zhang, Liu, Jin, Ma, Ma, Yuan: Control of basal autophagy by calpain1 mediated cleavage of ATG5. in Autophagy 2010
Show all 6 references for ABIN387794
Human Polyclonal ATG12 Primary Antibody for EIA, IHC (p) - ABIN497963
Jounai, Takeshita, Kobiyama, Sawano, Miyawaki, Xin, Ishii, Kawai, Akira, Suzuki, Okuda: The Atg5 Atg12 conjugate associates with innate antiviral immune responses. in Proceedings of the National Academy of Sciences of the United States of America 2007
Show all 5 references for ABIN497963
Human Polyclonal ATG12 Primary Antibody for EIA, IHC (p) - ABIN497964
Gozuacik, Kimchi: Autophagy as a cell death and tumor suppressor mechanism. in Oncogene 2004
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Human Polyclonal ATG12 Primary Antibody for IF, WB - ABIN387986
Tanida, Nishitani, Nemoto, Ueno, Kominami: Mammalian Apg12p, but not the Apg12p.Apg5p conjugate, facilitates LC3 processing. in Biochemical and biophysical research communications 2002
Show all 5 references for ABIN387986
Human Polyclonal ATG12 Primary Antibody for EIA, IHC (p) - ABIN1449610
Yee, Wilkinson, James, Ryan, Vousden: PUMA- and Bax-induced autophagy contributes to apoptosis. in Cell death and differentiation 2009
Show all 2 references for ABIN1449610
Human Polyclonal ATG12 Primary Antibody for IF (p), IHC (p) - ABIN752518
Song, Kou, Zou, Gao, Zeng, Xie: Involvement of autophagy in tri-ortho-cresyl phosphate- induced delayed neuropathy in hens. in Neurochemistry international 2013
Analysis of hepatitis B virus capsid maturation steps revealed that Rab33B and Atg5/12/16L1 are required for proper particle assembly and/or stability.
reveal a novel interconnection between autophagy, proteasome activity, and cell death mediated by the ubiquitin-like properties of ATG12
The results revealed that the expression of Atg12 and LC3 (show MAP1LC3A Antibodies) II/LC3 (show MAP1LC3A Antibodies) I in the chondrocytes treated with TXC increased, compared to that in the untreated chondrocytes
Cav-1 competitively interacts with the ATG12-ATG5 system to suppress the formation and function of the latter in lung epithelial cells.
ATG12 is a novel determinant of breast cancer primary resistance to HER1 (show EGFR Antibodies)/2-targeted therapeutics.
study to identify role of conjugation between ATG12 and ATG5 in LC3 lipidation; structural and mutational analyses of ATG12~ATG5-ATG16N revealed the conjugation generates a patch across ATG12 and ATG5 required for E3 activity
These data relate LC3B, ATG5 and ATG12 to mitochondrial quality control after oxidative damage, and to cellular longevity.
The Atg12 is as a positive mediator of mitochondrial apoptosis and show that Atg12 directly regulates the apoptotic pathway by binding and inactivating prosurvival Bcl-2 (show BCL2 Antibodies) family members, including Bcl-2 (show BCL2 Antibodies) and Mcl-1 (show MCL1 Antibodies).
Calpain1 plays an important role in controlling the levels of autophagy in normal living cells by regulating the levels of a key signaling molecule, ATG12-ATG5 conjugate.
Human Apg3p (show ATG3 Antibodies)/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16 (show GABARAPL2 Antibodies), GABARAP (show GABARAP Antibodies), and MAP-LC3 (show MAP1LC3A Antibodies), and facilitates the conjugation of hApg12p to hApg5p
Although genetic deletion of either Atg12 or Atg5 (show ATG5 Antibodies) renders POMC (show POMC Antibodies) neurons autophagy-deficient, mice lacking Atg5 (show ATG5 Antibodies) in POMC (show POMC Antibodies) neurons do not exhibit these phenotypes.
ATG12-ATG3 (show ATG3 Antibodies) interacts with Alix (show PDCD6IP Antibodies) to promote basal autophagic flux and late endosome function.
Atg5 (show ATG5 Antibodies)-Atg12/Atg16L1 (show ATG16L1 Antibodies) protein complex is required for IFNgamma-mediated host defense against murine norovirus infection.
Vaccinia virus actively disrupts the cellular autophagy through a novel molecular mechanism that is associated with aberrant LC3 (show MAP1LC3A Antibodies) lipidation and a direct conjugation between ATG12 and ATG3 (show ATG3 Antibodies).
Despite forming the Atg12-Atg5-Atg16L2 complex, Atg16L2 is not recruited to phagophores and is mostly present in the cytosol.
Autophagy participated the process of immune response of anti-MTB (show NCAPG2 Antibodies). Atg12 were the important molecule which control the formation of autophagy when MTB (show NCAPG2 Antibodies) infected.
Overexpression of Atg5 or Atg12 resulted in Atg5-Atg12 conjugate formation and suppression of RNA-mediated signaling.
Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998
autophagy-related protein 12
, ubiquitin-like protein ATG12
, ATG12 autophagy related 12 homolog
, Apg12 (autophagy, yeast) homolog
, autophagy-related 12
, potential preautophagosome nucleating protein Atg12