You are viewing an incomplete version of our website. Please click to reload the website as full version.

Autophagy Related 12 Proteins (ATG12)

Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. Additionally we are shipping ATG12 Antibodies (202) and ATG12 Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ATG12 9140 O94817
ATG12 67526 Q9CQY1
ATG12 361321 Q2TBJ5
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top ATG12 Proteins at antibodies-online.com

Showing 10 out of 19 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 0.05 mg Log in to see 2 to 3 Days
$275.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rice His tag   1 mg Log in to see 56 to 66 Days
$2,154.17
Details
Yeast Schizosaccharomyces pombe His tag   1 mg Log in to see 56 to 66 Days
$2,275.17
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,299.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,302.67
Details
Yeast REACT_Red bread mold His tag   1 mg Log in to see 56 to 66 Days
$2,352.17
Details
Yeast Candida albicans His tag   1 mg Log in to see 56 to 66 Days
$2,374.17
Details

ATG12 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Autophagy Related 12 (ATG12) Interaction Partners

Human Autophagy Related 12 (ATG12) interaction partners

  1. Analysis of hepatitis B virus capsid maturation steps revealed that Rab33B and Atg5/12/16L1 are required for proper particle assembly and/or stability.

  2. reveal a novel interconnection between autophagy, proteasome activity, and cell death mediated by the ubiquitin-like properties of ATG12

  3. The results revealed that the expression of Atg12 and LC3 (show MAP1LC3A Proteins) II/LC3 (show MAP1LC3A Proteins) I in the chondrocytes treated with TXC increased, compared to that in the untreated chondrocytes

  4. Cav-1 competitively interacts with the ATG12-ATG5 system to suppress the formation and function of the latter in lung epithelial cells.

  5. ATG12 is a novel determinant of breast cancer primary resistance to HER1 (show EGFR Proteins)/2-targeted therapeutics.

  6. study to identify role of conjugation between ATG12 and ATG5 in LC3 lipidation; structural and mutational analyses of ATG12~ATG5-ATG16N revealed the conjugation generates a patch across ATG12 and ATG5 required for E3 activity

  7. These data relate LC3B, ATG5 and ATG12 to mitochondrial quality control after oxidative damage, and to cellular longevity.

  8. The Atg12 is as a positive mediator of mitochondrial apoptosis and show that Atg12 directly regulates the apoptotic pathway by binding and inactivating prosurvival Bcl-2 (show BCL2 Proteins) family members, including Bcl-2 (show BCL2 Proteins) and Mcl-1 (show MCL1 Proteins).

  9. Calpain1 plays an important role in controlling the levels of autophagy in normal living cells by regulating the levels of a key signaling molecule, ATG12-ATG5 conjugate.

  10. Human Apg3p (show ATG3 Proteins)/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16 (show GABARAPL2 Proteins), GABARAP (show GABARAP Proteins), and MAP-LC3 (show MAP1LC3A Proteins), and facilitates the conjugation of hApg12p to hApg5p

Mouse (Murine) Autophagy Related 12 (ATG12) interaction partners

  1. Although genetic deletion of either Atg12 or Atg5 (show ATG5 Proteins) renders POMC (show POMC Proteins) neurons autophagy-deficient, mice lacking Atg5 (show ATG5 Proteins) in POMC (show POMC Proteins) neurons do not exhibit these phenotypes.

  2. ATG12-ATG3 (show ATG3 Proteins) interacts with Alix (show PDCD6IP Proteins) to promote basal autophagic flux and late endosome function.

  3. Atg5 (show ATG5 Proteins)-Atg12/Atg16L1 (show ATG16L1 Proteins) protein complex is required for IFNgamma-mediated host defense against murine norovirus infection.

  4. Vaccinia virus actively disrupts the cellular autophagy through a novel molecular mechanism that is associated with aberrant LC3 (show MAP1LC3A Proteins) lipidation and a direct conjugation between ATG12 and ATG3 (show ATG3 Proteins).

  5. Despite forming the Atg12-Atg5-Atg16L2 complex, Atg16L2 is not recruited to phagophores and is mostly present in the cytosol.

  6. Autophagy participated the process of immune response of anti-MTB (show NCAPG2 Proteins). Atg12 were the important molecule which control the formation of autophagy when MTB (show NCAPG2 Proteins) infected.

  7. Overexpression of Atg5 or Atg12 resulted in Atg5-Atg12 conjugate formation and suppression of RNA-mediated signaling.

ATG12 Protein Profile

Protein Summary

Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998

Gene names and symbols associated with Autophagy Related 12 Proteins (ATG12)

  • ATG12 autophagy related 12 homolog (S. cerevisiae) (ATG12)
  • autophagy related 12 (ATG12)
  • autophagy related 12 (Atg12)
  • similar to S. cerevisiae ATG12 (YBR217W) which nucleates preautophagosome formation as a conjugate with Atg5 (ATG12)
  • 4931423H11Rik protein
  • A330058M13Rik protein
  • APG12 protein
  • Apg12l protein
  • Atg12l protein
  • FBR93 protein
  • HAPG12 protein

Protein level used designations for Autophagy Related 12 Proteins (ATG12)

autophagy-related protein 12 , ubiquitin-like protein ATG12 , ATG12 autophagy related 12 homolog , Apg12 (autophagy, yeast) homolog , autophagy-related 12 , potential preautophagosome nucleating protein Atg12

GENE ID SPECIES
767903 Bos taurus
9140 Homo sapiens
67526 Mus musculus
361321 Rattus norvegicus
3636186 Candida albicans SC5314
Selected quality suppliers for ATG12 Proteins (ATG12)
Did you look for something else?