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BTLA encodes a member of the immunoglobulin superfamily. Additionally we are shipping BTLA Antibodies (188) and BTLA Kits (7) and many more products for this protein.
Showing 10 out of 22 products:
Human BTLA Protein expressed in HEK-293 Cells - ABIN2180655
Watanabe, Gavrieli, Sedy, Yang, Fallarino, Loftin, Hurchla, Zimmerman, Sim, Zang, Murphy, Russell, Allison, Murphy: BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1. in Nature immunology 2003
Show all 3 references for ABIN2180655
BTLA expression declines on B cells of the aged and is associated with low responsiveness to the trivalent influenza vaccine.
our study confirms that CD200 (show CD200 Proteins)/BTLA deletions are recurrent genetic lesions in the biology of BCP (show OPN1SW Proteins)-ALL
Focal deletions of the BTLA were associated with B-cell precursor acute lymphoblastic leukemia.
high BTLA expression levels in gastric cancer, identified by IHC, are an independent biomarker for the poor prognosis of patients with gastric cancer.
Data indicate taht lung function and the expressions of B, T lymphocyte attenuator (BTLA) and Treg cells were lower in patients with rheumatism than those in normal controls.
BTLA is a coreceptor that negatively regulates human Vgamma9Vdelta2 T-cell proliferation and has a role in immune escape for lymphoma cells
BTLA and HVEM (show TNFRSF14 Proteins) may have roles in graft rejection after kidney transplantation
BTLA regulates human B cell responses and has implications for future development of therapies modulating B cells.
The expression of BTLA has been observed on the surface of several kinds of cells within synovial tissues of RA patients, which indicates this signal might be involved in the regulation of local T cell activation and the pathogenesis of RA.
These findings support role for BTLA and/or HVEM (show TNFRSF14 Proteins) as potential, novel diagnostic markers of innate immune response/status and as therapeutic targets of sepsis.
Our findings indicate that BTLA may be involved in the control of inflammatory responses through increasing Foxp3 (show FOXP3 Proteins) expression, rather than attenuating IL-17 (show IL17A Proteins) production, in dextran sulfate sodium-induced colitis.
This study uncovers a BTLA-mediated strategy used by the host that permits Listeria proliferation to enable increasing T cell responses for long-term protection.
results support a model whereby BTLA on innate leukocytes is triggered by HVEM (show TNFRSF14 Proteins) and delivers negative signals into BTLA(+) cells, thereby interfering with the protective immune response to this intestinal parasite.
by coordinating expression of BTLA, RORgammat and IL-7 (show IL7 Proteins) balance suppressive and activation stimuli to regulate gammadelta T cell homeostasis and inflammatory responses
BTLA promotes the pathogenesis of virus-induced fulminant hepatitis by enhancing macrophage viability and function. Targeting BTLA may be a novel strategy for the treatment of FH.
B and T lymphocyte attenuator inhibits LPS (show TLR4 Proteins)-induced endotoxic shock by suppressing Toll-like receptor 4 (show TLR4 Proteins) signaling in innate immune cells.
Combined blockade of BTLA and herpesvirus entry mediator (HVEM (show TNFRSF14 Proteins)) does not inhibit donor T cell infiltration into graft-versus-host reaction organs; instead, it decreases the functional activity of the alloreactive T cells.
During increased resistance to malaria infection, BTLA regulates production of proinflammatory cytokines in a T cell-intrinsic way, while B cells intrinsically regulate the production of nonlethal Plasmodium yoelii 17NL-specific antibodies.
BTLA receptor is a potential immunoregulatory target for the modulation of cytotoxic T-lymphocyte-mediated
This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis.
B and T lymphocyte associated
, B and T lymphocyte attenuator
, B- and T-lymphocyte attenuator
, B- and T-lymphocyte-associated protein