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BTLA encodes a member of the immunoglobulin superfamily. Additionally we are shipping BTLA Antibodies (186) and BTLA Kits (6) and many more products for this protein.
Showing 10 out of 32 products:
Human BTLA Protein expressed in HEK-293 Cells - ABIN2180655
Watanabe, Gavrieli, Sedy, Yang, Fallarino, Loftin, Hurchla, Zimmerman, Sim, Zang, Murphy, Russell, Allison, Murphy: BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1. in Nature immunology 2003
Show all 3 references for 2180655
Plasma concentrations of soluble BTLA were increased early in sepsis/septic shock and correlated to severity of disease. A baseline concentration >21ng/mL was associated with a poor prognosis.
this study shows that in chronic hepatitis B virus patients, a subset of inefficient interferon-gamma (show IFNG Proteins) producing antigen-specific CD8 (show CD8A Proteins)+ T cells recruited to the liver expressed high BTLA levels
this study shows that BTLA expression is likely associated with positive rather than conventional negative regulation of CD11c (show ITGAX Proteins) antigen-presenting cell stimulatory capacity
rs1982809 BTLA gene polymorphism is associated with mRNA expression level and variations in the BTLA gene might be considered as potentially low-penetrating chronic lymphocytic leukemia risk factor
Study showed a decreased expression of BTLA in ocular Behcet's disease suggesting that it may be involved in the development and recurrence of this disease.
BTLA expression declines on B cells of the aged and is associated with low responsiveness to the trivalent influenza vaccine.
our study confirms that CD200 (show CD200 Proteins)/BTLA deletions are recurrent genetic lesions in the biology of BCP (show OPN1SW Proteins)-ALL
Focal deletions of the BTLA were associated with B-cell precursor acute lymphoblastic leukemia.
high BTLA expression levels in gastric cancer, identified by IHC, are an independent biomarker for the poor prognosis of patients with gastric cancer.
Data indicate taht lung function and the expressions of B, T lymphocyte attenuator (BTLA) and Treg cells were lower in patients with rheumatism than those in normal controls.
Dendritic cells require BTLA and HVEM (show TNFRSF14 Proteins) to actively adjust tolerizing T cell responses under steady-state conditions.
these data indicate that CCR7 (show CCR7 Proteins) and BTLA cooverexpression imparts an intermediate immune phenotype in mmature dendritic cells when compared to that in CCR7 (show CCR7 Proteins)- or BTLA-expressing counterparts that show a more immunocompetent or immunotolerant phenotype
this study shows that miR (show MLXIP Proteins)-155 is involved in the inhibition of BTLA during CD4 (show CD4 Proteins)+ T cell activation
Our findings indicate that BTLA may be involved in the control of inflammatory responses through increasing Foxp3 (show FOXP3 Proteins) expression, rather than attenuating IL-17 (show IL17A Proteins) production, in dextran sulfate sodium-induced colitis.
This study uncovers a BTLA-mediated strategy used by the host that permits Listeria proliferation to enable increasing T cell responses for long-term protection.
results support a model whereby BTLA on innate leukocytes is triggered by HVEM (show TNFRSF14 Proteins) and delivers negative signals into BTLA(+) cells, thereby interfering with the protective immune response to this intestinal parasite.
by coordinating expression of BTLA, RORgammat and IL-7 (show IL7 Proteins) balance suppressive and activation stimuli to regulate gammadelta T cell homeostasis and inflammatory responses
BTLA promotes the pathogenesis of virus-induced fulminant hepatitis by enhancing macrophage viability and function. Targeting BTLA may be a novel strategy for the treatment of FH.
B and T lymphocyte attenuator inhibits LPS (show TLR4 Proteins)-induced endotoxic shock by suppressing Toll-like receptor 4 (show TLR4 Proteins) signaling in innate immune cells.
These findings support role for BTLA and/or HVEM (show TNFRSF14 Proteins) as potential, novel diagnostic markers of innate immune response/status and as therapeutic targets of sepsis.
This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis.
B and T lymphocyte associated
, B and T lymphocyte attenuator
, B- and T-lymphocyte attenuator
, B- and T-lymphocyte-associated protein