anti-B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B) Antibodies

BCL11B encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Additionally we are shipping BCL11B Kits (7) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BCL11B 58208 Q99PV8
BCL11B 64919 Q9C0K0
BCL11B 314423  
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Top anti-BCL11B Antibodies at

Showing 10 out of 51 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
Cow Rabbit Un-conjugated WB WB Suggested Anti-BCL11B Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Jurkat cell lysate BCL11B is supported by BioGPS gene expression data to be expressed in Jurkat 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated WB BCL11B Antibody (Center) (ABIN654919) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the BCL11B antibody detected the BCL11B protein (arrow). 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated EIA, WB BCL11B Antibody (Center) western blot analysis in K562 cell line lysates (35µg/lane).This demonstrates the BCL11B antibody detected the BCL11B protein (arrow). 0.4 mL Log in to see 6 to 8 Days
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: BCL11B Sample Type: 293T Whole Cell lysates Antibody Dilution: 1.0ug/ml 100 μL Log in to see 2 to 3 Days
Bat Rabbit Un-conjugated IHC (p), WB Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) 0.1 mL Log in to see 7 to 9 Days
Human Rabbit Un-conjugated IF (p), IHC (p), WB Mouse embryonic cortex cells labeled with RABBIT ANTI-CTIP2 POLYCLONAL ANTIBODY Polyclonal Antibody, conjugated followed by DAPI staining Formalin-fixed and paraffin embedded human placenta labeled with Anti-IL-1 Beta/IL-1B Polyclonal Antibody, Unconjugated (ABIN1387746) at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
Human Rabbit Un-conjugated IHC (p), IP, IHC, WB Detection of Human Bcl11b by Western Blot and Immunoprecipitation. Samples: Nuclear extract (5 and 50 mcg for WB, 1 mg for IP) from Jurkat cells. Antibodies: ABIN153203 used at 0.1 mcg/ml (A) and 0.5 mcg/ml (B) for WB and at 1 and 10 mcg/mg lysate for IP (B). Bcl11b was also immunoprecipitated using affinity purified rabbit anti-Bcl11b antibodies ABIN153202 and ABIN153204 at 1 and 10 mcg/mg lysate. Normal rabbit IgG was used as a control for immunoprecipitation reactions. Detection: Chemiluminescence with exposure times of 1 minute (A), 1 second (B) or 30 seconds (B). Immunohistochemistry-Paraffin: BCL11B Antibody [ABIN153203] - Human stomach carcinoma. Antibody used at a dilution of 1:1000 (1ug/ml). 100 μL Log in to see 7 to 9 Days

BCL11B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) , ,

Human , , ,
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Rat (Rattus) ,

Top referenced anti-BCL11B Antibodies

  1. Human Polyclonal BCL11B Primary Antibody for ICC, IF - ABIN251041 : Beguin, Crépel, Aniksztejn, Becq, Pelosi, Pallesi-Pocachard, Bouamrane, Pasqualetti, Kitamura, Cardoso, Represa: An epilepsy-related ARX polyalanine expansion modifies glutamatergic neurons excitability and morphology without affecting GABAergic neurons development. in Cerebral cortex (New York, N.Y. : 1991) 2013 (PubMed)
    Show all 3 Pubmed References

More Antibodies against BCL11B Interaction Partners

Mouse (Murine) B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B) interaction partners

  1. Authors provide insight into the mechanism that underpins the repositioning of regulatory elements; identify a non-coding RNA, named ThymoD, which acts to reposition the Bcl11 enhancer away from the lamina to the nuclear interior and sequester the Bcl11b promoter and enhancer region into a single-loop domain.

  2. these results suggest that Bcl11b acts as a central intrinsic regulator of mammary epithelial stem cell quiescence.

  3. BCL11B is expressed in both osteogenic and sutural mesenchyme of the developing craniofacial complex. Bcl11b(-/-) mice exhibit increased proliferation of osteoprogenitors, premature osteoblast differentiation, and enhanced skull mineralization leading to synostoses of facial and calvarial sutures.

  4. this study shows that distinct, asynchronous and stage-specific transcription factors (TCF-1 (show HNF1A Antibodies), GATA-3 (show GATA3 Antibodies) and Runx1 (show RUNX1 Antibodies)) activate Bcl11b for T cell commitment

  5. the expression and function of Bcl11b in the oral epithelium and demonstration that Bcl11b is an essential regulator for keratinocyte differentiation and the morphogenesis of papillary structure of the lingual epithelium.

  6. BCL11B as a regulator of energy metabolism

  7. Data uncover for the first time a specific role of Bcl11b in adult hippocampal neurogenesis and function.

  8. BCL11B is extensively expressed in neocortical GABAergic interneurons of all three major subgroups and thus its expression is not restricted to subcerebral projections cells.

  9. Bcl11b regulates development of different thymocyte subsets at multiple stages and prevents an excess of innate CD8 (show CD8A Antibodies) single-positive thymocytes.

  10. Data indicate kinetic changes in relative phosphorylation on 18 of 23 serine and threonine residues and sumoylation on one of two lysine resides in B-cell lymphoma-leukemia 11B protein BCL11B.

Human B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B) interaction partners

  1. this is the first study to show that the inhibition of Bcl11b suppresses glioma cell growth by regulating the expression of the cell cycle regulator (show CDKN2A Antibodies) p21 (show CDKN1A Antibodies) and stemness-associated genes (Sox-2 (show SOX2 Antibodies)/Bmi-1 (show BMI1 Antibodies)).

  2. studies show BCL11B is a key regulator of the initial stages of human T-cell differentiation and delineate the BCL11B transcriptional program, enabling the dissection of the underpinnings of normal T-cell differentiation and providing a resource for understanding dysregulations in T-ALL

  3. BCL11B showed increased but varied expression in advanced tumor stage. Analysis of four patients receiving SAHA treatment suggested a positive correlation between BCL11B expression and favorable response to SAHA treatment. In conclusion, BCL11B may serve as a therapeutic target and a useful marker for improving HDACi efficacy in advanced CTCL (show TSPYL2 Antibodies).

  4. Human T-cell leukemia virus type 1 (HTLV-1) Tax (show CNTN2 Antibodies) directly binds to BCL11B. Tax (show CNTN2 Antibodies) enhances BCL11B degradation through proteasome pathway. Loss of BCL11B enhances cell growth in HTLV-1-infected cells.

  5. Findings identify BCL11B Ser2 (show JAG2 Antibodies) phosphorylation as a new mandatory step in the interconnected posttranslational modifications converting BCL11B from a transcriptional repressor to an activator.

  6. BCL11B introduction in human cell lines downregulated transcription of beta-catenin (show CTNNB1 Antibodies) target genes, whereas Bcl11b attenuation in Lgr5 (show LGR5 Antibodies)(+) crypt base columnar cells increased expression of beta-catenin (show CTNNB1 Antibodies) targets including c-Myc (show MYC Antibodies) and cyclin D1 (show CCND1 Antibodies).

  7. Tax (show CNTN2 Antibodies) is responsible for suppressing BCL11B protein expression in HTLV-1-infected T-cells; Tax (show CNTN2 Antibodies)-mediated repression of BCL11B is another mechanism that Tax (show CNTN2 Antibodies) uses to promote oncogenesis of HTLV-1-infected T-cells.

  8. low BCL11b expression was associated with poor prognosis; particularly in the standard risk group of thymic T-cell acute lymphoblastic leukemia

  9. Integrated genome-wide genotyping and gene expression profiling reveals BCL11B as a putative oncogene (show RAB1A Antibodies) in acute myeloid leukemia (show BCL11A Antibodies) with 14q32 aberrations.

  10. a comprehensive review of the roles of Bcl11b in progenitors, effector T cells, regulatory T cells, and invariant NKT (show SLC22A6 Antibodies) cells, as well as its impact on immune diseases.

BCL11B Antigen Profile

Protein Summary

This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported.

Gene names and symbols associated with BCL11B

  • B-cell CLL/lymphoma 11B (BCL11B) antibody
  • B cell leukemia/lymphoma 11B (Bcl11b) antibody
  • B-cell CLL/lymphoma 11B (zinc finger protein) (BCL11B) antibody
  • B-cell CLL/lymphoma 11B (Bcl11b) antibody
  • 9130430L19Rik antibody
  • AI604821 antibody
  • ATL1 antibody
  • ATL1-alpha antibody
  • ATL1-beta antibody
  • ATL1-delta antibody
  • ATL1-gamma antibody
  • B630002E05Rik antibody
  • BCL-11B antibody
  • BCL11B antibody
  • CTIP-2 antibody
  • CTIP2 antibody
  • hRIT1-alpha antibody
  • RIT1 antibody
  • ZNF856B antibody

Protein level used designations for BCL11B

B-cell CLL/lymphoma 11B (zinc finger protein) , B-cell CLL/lymphoma 11B , B-cell CLL/lymphoma 11B, isoform 1 , B-cell leukemia/lymphoma 11B , B-cell lymphoma/leukaemia 11B , B-cell lymphoma/leukemia 11B , COUP-TF interacting protein 2 , COUP-TF-interacting protein 2 , mRit1 , radiation-induced tumor suppressor gene 1 protein , B-cell CLL/lymphoma 11B/T-cell receptor delta constant region fusion protein , BCL-11B , BCL11B/TRDC fusion , hRit1 , zinc finger protein hRit1 alpha , B-cell lymphoma/leukemia 11B (predicted), 3 prime , B-cell lymphoma/leukemia 11B (predicted), 5 prime , COUP-TF-interacting protein 2 long form

423444 Gallus gallus
467548 Pan troglodytes
100137584 Papio anubis
58208 Mus musculus
64919 Homo sapiens
612476 Canis lupus familiaris
783269 Bos taurus
100328694 Oryctolagus cuniculus
314423 Rattus norvegicus
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