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anti-B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) Antibodies

BCL11A encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. Additionally we are shipping B-Cell CLL/lymphoma 11A (Zinc Finger Protein) Kits (7) and B-Cell CLL/lymphoma 11A (Zinc Finger Protein) Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BCL11A 14025 Q9QYE3
BCL11A 53335 Q9H165
BCL11A 305589  
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Top anti-B-Cell CLL/lymphoma 11A (Zinc Finger Protein) Antibodies at antibodies-online.com

Showing 10 out of 92 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of BCL11A Antibody (C-term) (ABIN653582) in Jurk... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of BCL11A Antibody (C-term) in Jurkat, Ramos, 29... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated WB Western Blot analysis of BCL11A expression in transfected 293T cell li... 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB Host: Rabbit  Target Name: Bcl11a  Sample Tissue: Mouse Heart lysates ... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Host: Rabbit  Target Name: Bcl11a  Sample Tissue: Rat Spleen lysates  ... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-BCL11A Antibody Titration: 0.2-1 ug/mlELISA Titer: 1... WB Suggested Anti-BCL11A  Antibody Titration: 0.2-1 µg/mL ELISA Titer:... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$566.50
Details
Human Rabbit Un-conjugated IHC (p), WB Human Thymus (formalin-fixed, paraffin-embedded) stained with BCL11A a... Human Spleen (formalin-fixed, paraffin-embedded) stained with BCL11A a... 50 μg Log in to see 8 to 10 Days
$676.50
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details

BCL11A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine) , , , ,

Human , , , ,
,
Rat (Rattus) , , , ,

Top referenced anti-B-Cell CLL/lymphoma 11A (Zinc Finger Protein) Antibodies

  1. Human Monoclonal BCL11A Primary Antibody for WB - ABIN395972 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for ABIN395972

  2. Human Polyclonal BCL11A Primary Antibody for WB - ABIN653582 : Solovieff, Milton, Hartley, Sherva, Sebastiani, Dworkis, Klings, Farrer, Garrett, Ashley-Koch, Telen, Fucharoen, Ha, Li, Chui, Baldwin, Steinberg: Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster. in Blood 2010 (PubMed)
    Show all 2 references for ABIN653582

  3. Human Polyclonal BCL11A Primary Antibody for EIA, WB - ABIN950622 : Nuinoon, Makarasara, Mushiroda, Setianingsih, Wahidiyat, Sripichai, Kumasaka, Takahashi, Svasti, Munkongdee, Mahasirimongkol, Peerapittayamongkol, Viprakasit, Kamatani, Winichagoon, Kubo, Nakamura, Fucharoen: A genome-wide association identified the common genetic variants influence disease severity in beta0-thalassemia/hemoglobin E. in Human genetics 2010 (PubMed)
    Show all 2 references for ABIN950622

  4. Chicken Polyclonal BCL11A Primary Antibody for IHC, WB - ABIN2781048 : Uda, Galanello, Sanna, Lettre, Sankaran, Chen, Usala, Busonero, Maschio, Albai, Piras, Sestu, Lai, Dei, Mulas, Crisponi, Naitza, Asunis, Deiana, Nagaraja, Perseu, Satta, Cipollina, Sollaino, Moi, Hirschhorn, Orkin, Abecasis, Schlessinger, Cao: Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

More Antibodies against B-Cell CLL/lymphoma 11A (Zinc Finger Protein) Interaction Partners

Mouse (Murine) B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) interaction partners

  1. deletion of Bcl11a alters the regulation of hematopoietic stem cell quiescence, self-renewal, and fate choice

  2. This study showed that the expression of Sema3c (show SEMA3C Antibodies) is increased in migrating Bcl11a-deficient neurons and that Bcl11a is a direct negative regulator of Sema3c (show SEMA3C Antibodies) transcription

  3. The results of this study support a role for CTIP1 on the specification of the Subcerebral Projection Neurons in layer 5 through the repression of TBR1 (show TBR1 Antibodies) and the promotion of CTIP2 (show BCL11B Antibodies) expression.

  4. Data indicate that Myb and BCL11A cooperate with DNMT1 to achieve developmental repression of embryonic and fetal beta-like human transgenic globin genes in the adult erythroid environment.

  5. BCL11A is an essential, lineage-specific factor that regulates plasmacytoid dendritic cell development, supporting a model wherein differentiation into pDCs represents a primed "default" pathway for common dendritic cell progenitors.

  6. Bcl11a controls Flt3 (show FLT3 Antibodies) expression in early hematopoietic progenitors and is required for pDC (show PDC Antibodies) development in vivo.

  7. Immunohistochemical staining of mouse brain showed strong expression of BCL11A in the cortical regions and also in the pyra (show NR2E1 Antibodies)midal cell (show NR2E3 Antibodies)layers in the CA1 and (show NR2F1 Antibodies) CA3 regions of the hippocampus.

  8. data support an important role for the KLF1-BCL11A axis in erythroid maturation and developmental regulation of globin expression

  9. The major B cell isoform, BCL11A-XL, binds the RAG1 (show RAG1 Antibodies) promoter and Erag enhancer to activate RAG1 (show RAG1 Antibodies) and RAG2 (show RAG2 Antibodies) transcription in pre-B cells.

  10. Overexpression of Bcl2 (show BCL2 Antibodies) and Mdm2 (show MDM2 Antibodies), or p53 (show TP53 Antibodies) deficiency, rescues both lethality and proliferative defects in Bcl11a-deficient early B cells.

Human B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) interaction partners

  1. Association has been found between variants at BCL11A erythroid-specific enhancer and fetal hemoglobin levels among sickle cell disease patients in Cameroon.

  2. These data suggest a possible role for BCL11A expression in acute myeloid leukaemia biology

  3. only HbF inducer efficient in rescuing the ability to differentiate along the erythroid program, even in K562 cell clones expressing high levels of BCL11A-XL, suggesting that BCL11A-XL activity is counteracted by mithramycin.

  4. a successful induction of gamma-globin (show HBG1 Antibodies) includes a reduction in BCL11A, KLF1 (show KLF1 Antibodies) and TAL1 (show TAL1 Antibodies) expression.

  5. this study found that LRF/ZBTB7A (show ZBTB7A Antibodies) transcription factor occupies fetal gamma-globin (show HBG1 Antibodies) genes and maintains the nucleosome density necessary for gamma-globin (show HBG1 Antibodies) gene silencing in adults, and that LRF (show ZBTB7A Antibodies) confers its repressive activity through a NuRD repressor complex independent of the fetal globin repressor BCL11A.

  6. BCL11A has an important role in triple-negative breast cancer and normal mammary epithelial cells

  7. The study compares polymorphism at BCL11A to HBS1L (show HBS1L Antibodies)-MYB (show MYB Antibodies) loci and explains less of the variance in HbF in patients with sickle cell disease in Cameroon.

  8. Common HbF BCL11A enhancer haplotypes in patients with African origin and Arab-Indian sickle cell anemia have similar effects on HbF but they do not explain their differences in HbF.

  9. the study of these rare patients and orthogonal genetic data demonstrates that BCL11A plays a central role in silencing HbF in humans and implicates BCL11A as an important factor for neurodevelopment

  10. SCF-mediated gamma-globin gene expression in adult human erythroid cells is associated with KLF1, BCL11A and SOX6 down-regulation.

B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) Antigen Profile

Protein Summary

This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene.

Gene names and symbols associated with BCL11A

  • B cell CLL/lymphoma 11A (zinc finger protein) (Bcl11a) antibody
  • B-cell CLL/lymphoma 11A (zinc finger protein) (BCL11A) antibody
  • B-cell CLL/lymphoma 11A (zinc finger protein) (bcl11a) antibody
  • B-cell CLL/lymphoma 11A (zinc finger protein) (Bcl11a) antibody
  • B-cell CLL/lymphoma 11Aa (bcl11aa) antibody
  • 2810047E18Rik antibody
  • BCL-11A antibody
  • bcl11a antibody
  • BCL11A-L antibody
  • BCL11a-M antibody
  • BCL11A-S antibody
  • BCL11A-XL antibody
  • CTIP1 antibody
  • D930021L15Rik antibody
  • EVI9 antibody
  • Evi9a antibody
  • Evi9b antibody
  • Evi9c antibody
  • HBFQTL5 antibody
  • mKIAA1809 antibody
  • wu:fi09f10 antibody
  • zgc:136898 antibody
  • ZNF856 antibody

Protein level used designations for BCL11A

B-cell CLL/lymphoma 11A (zinc finger protein) , B-cell lymphoma/leukemia 11A , COUP-TF interacting protein 1 , COUP-TF-interacting protein 1 , EVI-9 , ecotropic viral integration site 9 protein , myeloid leukemia , B-cell CLL/lymphoma 11A (zinc finger protein) isoform 2 , BCL-11A , BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) isoform 1 , C2H2-type zinc finger protein , ecotropic viral integration site 9 homolog , ecotropic viral integration site 9 protein homolog , zinc finger protein 856 , B-cell CLL/lymphoma 11A , bcl11a.1 , fi09f10

GENE ID SPECIES
14025 Mus musculus
53335 Homo sapiens
398877 Xenopus laevis
421199 Gallus gallus
481381 Canis lupus familiaris
538680 Bos taurus
305589 Rattus norvegicus
678650 Danio rerio
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