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B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) ELISA Kits

BCL11A encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. Additionally we are shipping BCL11A Antibodies (92) and BCL11A Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
BCL11A 14025 Q9QYE3
BCL11A 53335 Q9H165
Anti-Rat BCL11A BCL11A 305589  
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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.109 ng/mL 0.31-20 ng/mL 96 Tests Log in to see 9 to 11 Days
  96 Tests Log in to see 16 to 21 Days
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More ELISA Kits for BCL11A Interaction Partners

Mouse (Murine) B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) interaction partners

  1. deletion of Bcl11a alters the regulation of hematopoietic stem cell quiescence, self-renewal, and fate choice

  2. This study showed that the expression of Sema3c (show SEMA3C ELISA Kits) is increased in migrating Bcl11a-deficient neurons and that Bcl11a is a direct negative regulator of Sema3c (show SEMA3C ELISA Kits) transcription

  3. The results of this study support a role for CTIP1 on the specification of the Subcerebral Projection Neurons in layer 5 through the repression of TBR1 (show TBR1 ELISA Kits) and the promotion of CTIP2 (show BCL11B ELISA Kits) expression.

  4. Data indicate that Myb and BCL11A cooperate with DNMT1 to achieve developmental repression of embryonic and fetal beta-like human transgenic globin genes in the adult erythroid environment.

  5. BCL11A is an essential, lineage-specific factor that regulates plasmacytoid dendritic cell development, supporting a model wherein differentiation into pDCs represents a primed "default" pathway for common dendritic cell progenitors.

  6. Bcl11a controls Flt3 (show FLT3 ELISA Kits) expression in early hematopoietic progenitors and is required for pDC (show PDC ELISA Kits) development in vivo.

  7. Immunohistochemical staining of mouse brain showed strong expression of BCL11A in the cortical regions and also in the pyramidal cell layers in the CA1 (show CA1 ELISA Kits) and CA3 (show CA3 ELISA Kits) regions of the hippocampus.

  8. data support an important role for the KLF1-BCL11A axis in erythroid maturation and developmental regulation of globin expression

  9. The major B cell isoform, BCL11A-XL, binds the RAG1 (show RAG1 ELISA Kits) promoter and Erag enhancer to activate RAG1 (show RAG1 ELISA Kits) and RAG2 (show RAG2 ELISA Kits) transcription in pre-B cells.

  10. Overexpression of Bcl2 (show BCL2 ELISA Kits) and Mdm2 (show MDM2 ELISA Kits), or p53 (show TP53 ELISA Kits) deficiency, rescues both lethality and proliferative defects in Bcl11a-deficient early B cells.

Human B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) interaction partners

  1. Extensive genetic analyses have validated BCL11A as a potent repressor of fetal hemoglobin (show HBB ELISA Kits) level. Studies of BCL11A exemplify how contextual gene regulation may often be the substrate for trait-associated common genetic variation

  2. Association has been found between variants at BCL11A erythroid-specific enhancer and fetal hemoglobin levels among sickle cell disease patients in Cameroon.

  3. These data suggest a possible role for BCL11A expression in acute myeloid leukaemia biology

  4. only HbF inducer efficient in rescuing the ability to differentiate along the erythroid program, even in K562 cell clones expressing high levels of BCL11A-XL, suggesting that BCL11A-XL activity is counteracted by mithramycin.

  5. a successful induction of gamma-globin (show HBG1 ELISA Kits) includes a reduction in BCL11A, KLF1 (show KLF1 ELISA Kits) and TAL1 (show TAL1 ELISA Kits) expression.

  6. this study found that LRF/ZBTB7A (show ZBTB7A ELISA Kits) transcription factor occupies fetal gamma-globin (show HBG1 ELISA Kits) genes and maintains the nucleosome density necessary for gamma-globin (show HBG1 ELISA Kits) gene silencing in adults, and that LRF (show ZBTB7A ELISA Kits) confers its repressive activity through a NuRD repressor complex independent of the fetal globin repressor BCL11A.

  7. BCL11A has an important role in triple-negative breast cancer and normal mammary epithelial cells

  8. The study compares polymorphism at BCL11A to HBS1L (show HBS1L ELISA Kits)-MYB (show MYB ELISA Kits) loci and explains less of the variance in HbF in patients with sickle cell disease in Cameroon.

  9. Common HbF BCL11A enhancer haplotypes in patients with African origin and Arab-Indian sickle cell anemia have similar effects on HbF but they do not explain their differences in HbF.

  10. the study of these rare patients and orthogonal genetic data demonstrates that BCL11A plays a central role in silencing HbF in humans and implicates BCL11A as an important factor for neurodevelopment

BCL11A Antigen Profile

Antigen Summary

This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene.

Gene names and symbols associated with BCL11A

  • B cell CLL/lymphoma 11A (zinc finger protein) (Bcl11a) antibody
  • B-cell CLL/lymphoma 11A (zinc finger protein) (BCL11A) antibody
  • B-cell CLL/lymphoma 11A (zinc finger protein) (bcl11a) antibody
  • B-cell CLL/lymphoma 11A (zinc finger protein) (Bcl11a) antibody
  • B-cell CLL/lymphoma 11Aa (bcl11aa) antibody
  • 2810047E18Rik antibody
  • BCL-11A antibody
  • bcl11a antibody
  • BCL11A-L antibody
  • BCL11a-M antibody
  • BCL11A-S antibody
  • BCL11A-XL antibody
  • CTIP1 antibody
  • D930021L15Rik antibody
  • EVI9 antibody
  • Evi9a antibody
  • Evi9b antibody
  • Evi9c antibody
  • HBFQTL5 antibody
  • mKIAA1809 antibody
  • wu:fi09f10 antibody
  • zgc:136898 antibody
  • ZNF856 antibody

Protein level used designations for BCL11A

B-cell CLL/lymphoma 11A (zinc finger protein) , B-cell lymphoma/leukemia 11A , COUP-TF interacting protein 1 , COUP-TF-interacting protein 1 , EVI-9 , ecotropic viral integration site 9 protein , myeloid leukemia , B-cell CLL/lymphoma 11A (zinc finger protein) isoform 2 , BCL-11A , BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) isoform 1 , C2H2-type zinc finger protein , ecotropic viral integration site 9 homolog , ecotropic viral integration site 9 protein homolog , zinc finger protein 856 , B-cell CLL/lymphoma 11A , bcl11a.1 , fi09f10

14025 Mus musculus
53335 Homo sapiens
398877 Xenopus laevis
421199 Gallus gallus
481381 Canis lupus familiaris
538680 Bos taurus
305589 Rattus norvegicus
678650 Danio rerio
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