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anti-B-Cell CLL/lymphoma 6 (BCL6) Antibodies

The protein encoded by BCL6 is a zinc finger transcription factor and contains an N-terminal POZ domain. Additionally we are shipping BCL6 Proteins (11) and BCL6 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BCL6 12053 P41183
BCL6 604 P41182
BCL6 303836  
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Top anti-BCL6 Antibodies at antibodies-online.com

Showing 10 out of 164 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from COLO205 cells treated with insulin 0.01U/ml 15', using Bcl-6 (Phospho-Ser333) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB BCL6 Antibody (C-term) (ABIN656985) western blot analysis in Hela cell line lysates (35 µg/lane). This demonstrates the BCL6 antibody detected the BCL6 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IF, WB BCL6 Antibody (C-term)  western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the BCL6 antibody detected the BCL6 protein (arrow). Confocal immunofluorescent analysis of BCL6 Antibody (C-term) (ascites)  with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-mouse lgG (green).Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). 0.1 mL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB BCL6 Antibody (C-term) western blot analysis in Hela cell line lysates (35µg/lane).This demonstrates the BCL6 antibody detected the BCL6 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from 293 cells, using Bcl-6 (Ab-333) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of Bcl-6 Antibody (C-term) (ABIN391554) in mouse cerebellum tissue lysates (35 µg/lane). BCL6 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lymph tissue with Bcl-6 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of BCL6 in rat lung tissue lysate with Bcl6 Antibody  at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated IHC (p), ICS, WB Analysis of Bcl-6 expression by Western blot and Immunohistochemistry. Western blot analysis of Bcl-6 expressed by Human Jurkat (ABIN968537) and Ramos cell lines. Cell lysates from untreated Jurkat (lanes 1-5) and Ramos (lanes 6-10) cells (15 µg total cellular protein/lane) were electrophoresed (SDS-PAGE), transferred to membranes and then probed with Purified Mouse Anti-Bcl-6 antibody (Clone K112-91, ABIN967677) at concentrations of 2 (lanes 1, 6), 0.667 (lanes 2, 7), 0.222 (lanes 3, 8), 0.074 (lanes 4, 9) and 0.025 (lanes 5, 10) µg/ml. Bcl-6 is identified as a band of ~87-98 kDa in the Ramos cell lysate. 0.1 mg Log in to see 5 to 6 Days
$266.81
Details
Human Rabbit Un-conjugated WB Western Blot: Bcl-6 Antibody [NBP2-24952] - Analysis of Bcl6 in 20 ugs of Ramos cell lysate using NBP2-24952 at 1 ug/ml. 0.1 mg Log in to see 5 to 7 Days
$317.63
Details
Human Rabbit Un-conjugated IHC (p), IP, Neut, WB 0.1 mg Log in to see 6 to 8 Days
$412.50
Details

BCL6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-BCL6 Antibodies

  1. Human Monoclonal BCL6 Primary Antibody for IHC (p), ICS - ABIN967677 : Baumjohann, Okada, Ansel: Cutting Edge: Distinct waves of BCL6 expression during T follicular helper cell development. in Journal of immunology (Baltimore, Md. : 1950) 2011 (PubMed)
    Show all 10 references for ABIN967677

  2. Human Polyclonal BCL6 Primary Antibody for WB - ABIN656985 : Chang, Vlad, DAgati, Liu, Zhang, Witkowski, Torkamani, Stokes, Ho, Cortesini, Suciu-Foca: BCL6 is required for differentiation of Ig-like transcript 3-Fc-induced CD8+ T suppressor cells. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 4 references for ABIN656985

  3. Human Monoclonal BCL6 Primary Antibody for IF, WB - ABIN659194 : Yang, Huang, Chatterjee, Twait, Fisher: A novel mechanism involving coordinated regulation of nuclear levels and acetylation of NF-YA and Bcl6 activates RGS4 transcription. in The Journal of biological chemistry 2010 (PubMed)
    Show all 4 references for ABIN659194

  4. Human Polyclonal BCL6 Primary Antibody for EIA, WB - ABIN950636 : Lai, Fatemi, Dhasarathy, Malone, Sobol, Geigerman, Jaye, Mav, Shah, Li, Wade: DNA methylation prevents CTCF-mediated silencing of the oncogene BCL6 in B cell lymphomas. in The Journal of experimental medicine 2010 (PubMed)
    Show all 3 references for ABIN950636

  5. Human Polyclonal BCL6 Primary Antibody for EIA, WB - ABIN1449999 : Lee, Kim, Sivula, Strittmatter: Nogo receptor antagonism promotes stroke recovery by enhancing axonal plasticity. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2004 (PubMed)
    Show all 2 references for ABIN1449999

  6. Human Polyclonal BCL6 Primary Antibody for ELISA, WB - ABIN1533156 : Ye, Lista, Lo Coco, Knowles, Offit, Chaganti, Dalla-Favera: Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma. in Science (New York, N.Y.) 1993 (PubMed)
    Show all 2 references for ABIN1533156

  7. Human Polyclonal BCL6 Primary Antibody for FACS, IHC (p) - ABIN391554 : Saito, Novak, Piovan, Basso, Sumazin, Schneider, Crespo, Shen, Bhagat, Califano, Chadburn, Pasqualucci, Dalla-Favera: BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma. in Proceedings of the National Academy of Sciences of the United States of America 2009 (PubMed)
    Show all 2 references for ABIN391554

  8. Human Polyclonal BCL6 Primary Antibody for ELISA, WB - ABIN1532126 : Miki, Kawamata, Hirosawa, Aoki: Gene involved in the 3q27 translocation associated with B-cell lymphoma, BCL5, encodes a Krüppel-like zinc-finger protein. in Blood 1994 (PubMed)
    Show all 2 references for ABIN1532126

  9. Human Polyclonal BCL6 Primary Antibody for WB - ABIN4283623 : Margalit, Amram, Amariglio, Simon, Shaklai, Granot, Minsky, Shimoni, Harmelin, Givol, Shohat, Oren, Rechavi: BCL6 is regulated by p53 through a response element frequently disrupted in B-cell non-Hodgkin lymphoma. in Blood 2006 (PubMed)

More Antibodies against BCL6 Interaction Partners

Xenopus laevis B-Cell CLL/lymphoma 6 (BCL6) interaction partners

  1. BCL6 forms a complex with BCL6 corepressor (BCoR (show BCOR Antibodies)) on the promoters of selected Notch (show NOTCH1 Antibodies) target genes such as enhancer of split related 1.

Mouse (Murine) B-Cell CLL/lymphoma 6 (BCL6) interaction partners

  1. synergistic activity of Card11 (show CARD11 Antibodies) mutant and Bcl6 in the development of diffuse large B-cell lymphoma in a mouse model

  2. Bcl6, by interacting with the co-factors NcoR2 (show NCOR2 Antibodies) and HDAC3 (show HDAC3 Antibodies), plays a pivotal role in controlling IRF7 (show IRF7 Antibodies) induction and antiviral signaling priming.

  3. Bcl6 promoted T follicular helper cell differentiation through antagonizing IL-7R / STAT5a (show STAT5A Antibodies) axis.

  4. Bob1 (show POU2AF1 Antibodies) directly binds to and transactivate the Bcl6 promoter during the development of follicular T helper cells .

  5. upon binding to a composite NFAT (show NFATC1 Antibodies)/BCL6 regulatory element within the Ccl2 (show CCL2 Antibodies) promoter, NFATc1 (show NFATC1 Antibodies)/beta proteins release the BCL6-dependent repression of Ccl2 (show CCL2 Antibodies) gene in macrophages.

  6. transferred Bcl6-deficient T cells into wildtype hosts. Bcl6-deficient T cells did not develop into GC Tfh, but they still generated CXCR5 (show CXCR5 Antibodies)+ IFN-gamma (show IFNG Antibodies)+ IL-21 (show IL21 Antibodies)+ IL-10 (show IL10 Antibodies)+ Teff, suggesting that this predominant population is not of the Tfh-lineage

  7. Bcl6 middle domain repressor function is required for T follicular helper cell differentiation and utilizes the corepressor MTA3 (show MTA3 Antibodies).

  8. Data indicate that signal transducer and activator of transcription 3 (Stat3 (show STAT3 Antibodies)) can repress the expression of transcription factor Bcl6 and interleukin-4 (IL-4 (show IL4 Antibodies)) in follicular helper T (TFH) cells.

  9. Enforced expression of BCL6 in EGR2 (show EGR2 Antibodies)/3-deficient CD4 (show CD4 Antibodies) T cells partially restored Tfh differentiation and GC formation in response to virus infection

  10. PRMT7 (show PRMT7 Antibodies) could recruit H4R3me1 and symmetric H4R3me2 to the Bcl6 promoter. These results provide evidence for the important roles played by PRMT7 (show PRMT7 Antibodies) in germinal center formation.

Human B-Cell CLL/lymphoma 6 (BCL6) interaction partners

  1. miR (show MLXIP Antibodies)-339-5p inhibits migration and invasion in ovarian cancer by targeting NACC1 (show NACC1 Antibodies) and BCL6. miR (show MLXIP Antibodies)-339-5p may be a biomarker of metastasis in ovarian cancer; NACC1 (show NACC1 Antibodies) had a predictive value for ovarian cancer progression

  2. Data show there was a positive correlation between B cell lymphoma 6 (Bcl-6) and B lymphocyte-induced maturation protein 1 (Blimp-1 (show PRDM1 Antibodies)) at the level of mRNA.

  3. miR (show MLXIP Antibodies)-155 overexpression plays a promoting role in the proliferative, migratory and invasive behavior of OSCC cells. Its effects on OSCC are possibly associated with its regulation of the BCL6/cyclin D2 (show CCND2 Antibodies) axis.

  4. BCL6 Rearrangements are associated with Diffuse Large B-Cell Lymphoma.

  5. Bcl6, by interacting with the co-factors NcoR2 (show NCOR2 Antibodies) and HDAC3 (show HDAC3 Antibodies), plays a pivotal role in controlling IRF7 (show IRF7 Antibodies) induction and antiviral signaling priming.

  6. diffuse large B-cell lymphoma patients with either MYC (show MYC Antibodies)/BCL6 rearrangements or MYC (show MYC Antibodies)/BCL6 co-expression did not always have poorer prognosis

  7. BCL6 promotes proliferation and survival of trophoblastic cells.

  8. Studies indicate that germinal centers (GC) B (show NPR2 Antibodies) cells represent the normal counterpart of most B-cell lymphomas, which are often characterized by deregulated B cell lymphoma 6 (BCL6) expression or BCL6-mediated pathways.

  9. Bcl-6 mRNA and protein levels, as well as the frequencies of Bcl-6(+)CD4 (show CD4 Antibodies)(+) cells were significantly increased in polyp tissues compared with normal controls.

  10. Follicular helper T cells differentiation is a multistage process involving BCL6 and other transcription factors, cytokines, and costimulation through ICOS (show CTLA4 Antibodies) and several other molecules. (Review)

BCL6 Antigen Profile

Protein Summary

The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

Gene names and symbols associated with BCL6

  • B-cell CLL/lymphoma 6 (bcl6) antibody
  • B-cell CLL/lymphoma 6 (BCL6) antibody
  • B cell leukemia/lymphoma 6 (Bcl6) antibody
  • B-cell CLL/lymphoma 6 (Bcl6) antibody
  • BCL5 antibody
  • BCL6A antibody
  • LAZ3 antibody
  • MGC132260 antibody
  • ZBTB27 antibody
  • ZNF51 antibody

Protein level used designations for BCL6

B-cell CLL/lymphoma 6 , B-cell CLL/lymphoma 6 (zinc finger protein 51) , B-cell lymphoma 6 protein , zinc finger protein 51 , B-cell leukemia/lymphoma 5 , B-cell leukemia/lymphoma 6 , B-cell lymphoma 6 protein homolog , B-cell lymphoma 5 protein , B-cell lymphoma 6 protein transcript , BCL-5 , BCL-6 , cys-his2 zinc finger transcription factor , lymphoma-associated zinc finger gene on chromosome 3 , protein LAZ-3 , zinc finger and BTB domain-containing protein 27 , zinc finger transcription factor BCL6S

GENE ID SPECIES
495412 Xenopus laevis
100126063 Xenopus (Silurana) tropicalis
100294564 Pongo abelii
488124 Canis lupus familiaris
12053 Mus musculus
604 Homo sapiens
303836 Rattus norvegicus
100156549 Sus scrofa
539020 Bos taurus
101110557 Ovis aries
100353941 Oryctolagus cuniculus
424912 Gallus gallus
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