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B-Cell CLL/lymphoma 6 (BCL6) ELISA Kits

The protein encoded by BCL6 is a zinc finger transcription factor and contains an N-terminal POZ domain. Additionally we are shipping BCL6 Antibodies (157) and BCL6 Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
BCL6 12053 P41183
BCL6 604 P41182
BCL6 303836  
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More ELISA Kits for BCL6 Interaction Partners

Xenopus laevis B-Cell CLL/lymphoma 6 (BCL6) interaction partners

  1. BCL6 forms a complex with BCL6 corepressor (BCoR (show BCOR ELISA Kits)) on the promoters of selected Notch (show NOTCH1 ELISA Kits) target genes such as enhancer of split related 1.

Mouse (Murine) B-Cell CLL/lymphoma 6 (BCL6) interaction partners

  1. Bob1 (show POU2AF1 ELISA Kits) directly binds to and transactivate the Bcl6 promoter during the development of follicular T helper cells .

  2. upon binding to a composite NFAT (show NFATC1 ELISA Kits)/BCL6 regulatory element within the Ccl2 (show CCL2 ELISA Kits) promoter, NFATc1 (show NFATC1 ELISA Kits)/beta proteins release the BCL6-dependent repression of Ccl2 (show CCL2 ELISA Kits) gene in macrophages.

  3. transferred Bcl6-deficient T cells into wildtype hosts. Bcl6-deficient T cells did not develop into GC Tfh, but they still generated CXCR5 (show CXCR5 ELISA Kits)+ IFN-gamma (show IFNG ELISA Kits)+ IL-21 (show IL21 ELISA Kits)+ IL-10 (show IL10 ELISA Kits)+ Teff, suggesting that this predominant population is not of the Tfh-lineage

  4. Bcl6 middle domain repressor function is required for T follicular helper cell differentiation and utilizes the corepressor MTA3 (show MTA3 ELISA Kits).

  5. Data indicate that signal transducer and activator of transcription 3 (Stat3 (show STAT3 ELISA Kits)) can repress the expression of transcription factor Bcl6 and interleukin-4 (IL-4 (show IL4 ELISA Kits)) in follicular helper T (TFH) cells.

  6. Enforced expression of BCL6 in EGR2 (show EGR2 ELISA Kits)/3-deficient CD4 (show CD4 ELISA Kits) T cells partially restored Tfh differentiation and GC formation in response to virus infection

  7. PRMT7 (show PRMT7 ELISA Kits) could recruit H4R3me1 and symmetric H4R3me2 to the Bcl6 promoter. These results provide evidence for the important roles played by PRMT7 (show PRMT7 ELISA Kits) in germinal center formation.

  8. Blimp1 (show PRDM1 ELISA Kits) (encoded by Prdm1 (show PRDM1 ELISA Kits)) inhibits T(FH) differentiation by antagonizing Bcl-6. TCF-1 (show HNF1A ELISA Kits) promoted Bcl-6 expression but repressed Blimp1 (show PRDM1 ELISA Kits) expression.

  9. Transiently expressing Bcl6 in HSPCs causes mature B-cell lymphomas that lack Bcl6 expression and target-gene repression, are transcriptionally similar to post-GCB cells, and show epigenetic changes that are conserved from HSPCs to mature B-cells.

  10. these data suggest that the Bcl6 BTB domain is a key mediator of the differentiation of Tfh cells.

Human B-Cell CLL/lymphoma 6 (BCL6) interaction partners

  1. Studies indicate that germinal centers (GC) B (show NPR2 ELISA Kits) cells represent the normal counterpart of most B-cell lymphomas, which are often characterized by deregulated B cell lymphoma 6 (BCL6) expression or BCL6-mediated pathways.

  2. Bcl-6 mRNA and protein levels, as well as the frequencies of Bcl-6(+)CD4 (show CD4 ELISA Kits)(+) cells were significantly increased in polyp tissues compared with normal controls.

  3. Follicular helper T cells differentiation is a multistage process involving BCL6 and other transcription factors, cytokines, and costimulation through ICOS (show CTLA4 ELISA Kits) and several other molecules. (Review)

  4. These results suggest that STAT6 (show STAT6 ELISA Kits) plays an important role in regulating Sp1 (show PSG1 ELISA Kits) and BCL6 through STAT2 (show STAT2 ELISA Kits) to exert the anti-proliferative effects of type I IFN.

  5. Identified BCL6 to be a target of miR (show MLXIP ELISA Kits)-10a in patients with Acute Myeloid Leukemia (show BCL11A ELISA Kits) (AML (show RUNX1 ELISA Kits)).

  6. Study demonstrates that survivin (show BIRC5 ELISA Kits) belongs to the Tfh cell phenotype and ensures their optimal function by regulating transcriptional activity of Bcl-6.

  7. BCL6 repression of EP300 (show EP300 ELISA Kits) in human diffuse large B cell lymphoma cells provides a basis for rational combinatorial therapy.

  8. Taken together, our results demonstrated that miR (show MLXIP ELISA Kits)-187-3p played a pivotal role on NSCLC through inhibiting cell proliferation, migration, invasion, and promoting apoptosis by targeting oncogenic BCL6.

  9. BCL6 gene expression is plays a role in the pathogenesis of diffuse large B-cell lymphoma.

  10. Non-Hodgkin lymphomas with MYC (show MYC ELISA Kits)+/BCL2 (show BCL2 ELISA Kits)+/BCL6- gene rearrangements was more likely to have a non-germinal center cell of origin than MYC (show MYC ELISA Kits)+/BCL2 (show BCL2 ELISA Kits)-/BCL6+ and MYC (show MYC ELISA Kits)+/BCL2 (show BCL2 ELISA Kits)+/BCL6+ lymphomas.

BCL6 Antigen Profile

Antigen Summary

The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

Gene names and symbols associated with B-Cell CLL/lymphoma 6 (BCL6) ELISA Kits

  • B-cell CLL/lymphoma 6 (bcl6) antibody
  • B-cell CLL/lymphoma 6 (BCL6) antibody
  • B cell leukemia/lymphoma 6 (Bcl6) antibody
  • B-cell CLL/lymphoma 6 (Bcl6) antibody
  • BCL5 antibody
  • BCL6A antibody
  • LAZ3 antibody
  • MGC132260 antibody
  • ZBTB27 antibody
  • ZNF51 antibody

Protein level used designations for B-Cell CLL/lymphoma 6 (BCL6) ELISA Kits

B-cell CLL/lymphoma 6 , B-cell CLL/lymphoma 6 (zinc finger protein 51) , B-cell lymphoma 6 protein , zinc finger protein 51 , B-cell leukemia/lymphoma 5 , B-cell leukemia/lymphoma 6 , B-cell lymphoma 6 protein homolog , B-cell lymphoma 5 protein , B-cell lymphoma 6 protein transcript , BCL-5 , BCL-6 , cys-his2 zinc finger transcription factor , lymphoma-associated zinc finger gene on chromosome 3 , protein LAZ-3 , zinc finger and BTB domain-containing protein 27 , zinc finger transcription factor BCL6S

495412 Xenopus laevis
100126063 Xenopus (Silurana) tropicalis
100294564 Pongo abelii
488124 Canis lupus familiaris
12053 Mus musculus
604 Homo sapiens
303836 Rattus norvegicus
100156549 Sus scrofa
539020 Bos taurus
101110557 Ovis aries
100353941 Oryctolagus cuniculus
424912 Gallus gallus
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