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BCL7A is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. Additionally we are shipping B-Cell CLL/lymphoma 7A Antibodies (51) and many more products for this protein.
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Human BCL7A Protein expressed in Escherichia coli (E. coli) - ABIN1098485
Carbone, Bernardini, Valenzano, Bottillo, De Simone, Capizzi, Capalbo, Romano, Novelli, Dallapiccola, Amerio: Array-based comparative genomic hybridization in early-stage mycosis fungoides: recurrent deletion of tumor suppressor genes BCL7A, SMAC/DIABLO, and RHOF. in Genes, chromosomes & cancer 2008
Show all 2 references for ABIN1098485
Data suggest that BCL7A may play an important role in cutaneous T-cell lymphoma (CTCL (show TSPYL2 Proteins)) carcinogenesis.
Report describes BCL7A protein expression in normal lymphoid tissues and lymphomas using immunohistochemistry.
Promoter hypermethylation of BCL7a is associated with cutaneous T-cell lymphoma
deletion of genes BCL7A in early-stage mycosis fungoides.
Variants in BCL7A were strongly related to diffuse large B-cell lymphoma.
This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene.
B-cell CLL/lymphoma 7A
, B-cell CLL/lymphoma 7 protein family member A
, B-cell CLL/lymphoma-7