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BCL7B encodes a member of the BCL7 family including BCL7A, BCL7B and BCL7C proteins. Additionally we are shipping B-Cell CLL/lymphoma 7B Antibodies (52) and many more products for this protein.
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We herewith propose that the BCL7B gene, located in the chromosomal region commonly deleted in Williams syndrome, could potentially have a role in this particular association.
our data indicate that BCL7B/BCL-7 (show BCL7A Proteins) has some roles in maintaining the structure of nuclei and is involved in the modulation of multiple pathways, including Wnt (show WNT2 Proteins) and apoptosis.
BCL7B gene deltion is associated with Williams-Beuren Syndrome leading to Burkitt Leukemia.
This gene encodes a member of the BCL7 family including BCL7A, BCL7B and BCL7C proteins. This member is BCL7B, which contains a region that is highly similar to the N-terminal segment of BCL7A or BCL7C proteins. The BCL7A protein is encoded by the gene known to be directly involved in a three-way gene translocation in a Burkitt lymphoma cell line. This gene is located at a chromosomal region commonly deleted in Williams syndrome. This gene is highly conserved from C. elegans to human. Multiple alternatively spliced transcript variants have been found for this gene.
B-cell CLL/lymphoma 7 protein family member B-B
, B-cell CLL/lymphoma 7 protein family member B
, B-cell CLL/lymphoma 7 protein family member B-A
, B-cell CLL/lymphoma 7B
, B-cell CLL/lymphoma 7b