You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-B-Cell Linker (BLNK) Antibodies

BLNK encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. Additionally we are shipping B-Cell Linker Kits (44) and B-Cell Linker Proteins (14) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BLNK 17060 Q9QUN3
BLNK 29760 Q8WV28
BLNK 499356 Q4KM52
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-B-Cell Linker Antibodies at antibodies-online.com

Showing 10 out of 189 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-BLNK Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:3... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of BLNK (arrow) using rabbit polyclonal BLNK Ant... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from K562 cells treated with starved... Immunohistochemistry analysis of paraffin-embedded human brain, using ... 100 μg Log in to see 2 to 3 Days
$275.00
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Goat Un-conjugated EIA, WB 20 μg Log in to see 6 to 8 Days
$203.50
Details
Human Goat Un-conjugated ELISA, WB ABIN184602 staining (4µg/ml) of Daudi lysate (RIPA buffer, 30µg total ... 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of BLNK Antibody (Center) (ABIN390395) in NCI-H4... BLNK Antibody (Center) (ABIN390395) IHC analysis in formalin fixed and... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4... Formalin-fixed and paraffin embedded human lung carcinoma labeled with... 100 μL Log in to see 3 to 7 Days
$291.50
Details
Human Mouse Un-conjugated WB Western blot analysis of BLNK (pY84) in human Burkitt’s lymphoma. Lysa... 0.1 mg Log in to see 5 to 6 Days
$423.33
Details
Human Mouse Un-conjugated ICC, FACS, IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green... Figure 2: Flow cytometric analysis of NIH/3T3 cells using BLNK mouse m... 100 μL Log in to see 3 to 4 Days
$430.10
Details

BLNK Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine) , , , ,
, ,
Human , , , ,
, ,
Rat (Rattus) , , , ,
,

Top referenced anti-B-Cell Linker Antibodies

  1. Human Monoclonal BLNK Primary Antibody for WB - ABIN967596 : Chiu, Dalton, Ishiai, Kurosaki, Chan: BLNK: molecular scaffolding through 'cis'-mediated organization of signaling proteins. in The EMBO journal 2002 (PubMed)
    Show all 5 references for ABIN967596

  2. Human Polyclonal BLNK Primary Antibody for WB - ABIN657356 : Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: New genetic associations detected in a host response study to hepatitis B vaccine. in Genes and immunity 2010 (PubMed)
    Show all 4 references for ABIN657356

  3. Human Monoclonal BLNK Primary Antibody for ICC, FACS - ABIN968984 : Imamura, Oda, Katahira, Bundo, Pike, Ratcliffe, Kitamura: BLNK binds active H-Ras to promote B cell receptor-mediated capping and ERK activation. in The Journal of biological chemistry 2009 (PubMed)
    Show all 2 references for ABIN968984

  4. Human Polyclonal BLNK Primary Antibody for IHC, ELISA - ABIN1532093 : Fu, Turck, Kurosaki, Chan: BLNK: a central linker protein in B cell activation. in Immunity 1998 (PubMed)
    Show all 2 references for ABIN1532093

  5. Human Polyclonal BLNK Primary Antibody for EIA, WB - ABIN452784 : Kamino, Futamura, Nakamura, Kitamura, Kabu, Arakawa: B-cell linker protein prevents aneuploidy by inhibiting cytokinesis. in Cancer science 2008 (PubMed)
    Show all 2 references for ABIN452784

  6. Human Polyclonal BLNK Primary Antibody for IF (p), IHC (p) - ABIN683458 : Luger, Yang, Raviv, Weinberg, Banerjee, Lee, Trepel, Yang, Wakefield: Expression of the B-cell receptor component CD79a on immature myeloid cells contributes to their tumor promoting effects. in PLoS ONE 2013 (PubMed)

  7. Human Polyclonal BLNK Primary Antibody for WB - ABIN2782531 : Röck, Schneider, Grün, Grützkau, Küppers, Schmitz, Winkels: CD303 (BDCA-2) signals in plasmacytoid dendritic cells via a BCR-like signalosome involving Syk, Slp65 and PLCgamma2. in European journal of immunology 2007 (PubMed)

More Antibodies against B-Cell Linker Interaction Partners

Mouse (Murine) B-Cell Linker (BLNK) interaction partners

  1. Authors demonstrate leukemogenicity of PAX5 (show PAX5 Antibodies)-PML (show PML Antibodies) by introducing it into normal mouse pro-B cells; B-cell linker protein (Blnk) is repressed by PAX5 (show PAX5 Antibodies)-PML (show PML Antibodies) in leukemia cells; enforced expression of Blnk increases survival despite introduction of PAX5 (show PAX5 Antibodies)-PML (show PML Antibodies).

  2. B-cell linker protein expression contributes to controlling allergic and autoimmune diseases by mediating IL-10 (show IL10 Antibodies) production in regulatory B cells.

  3. Tumor suppressor BLNK is a target of transcriptional activation by PU.1 and Spi-B (show SPIB Antibodies) in the B cell lineage.

  4. a novel negative feedback regulation of BCR (show BCR Antibodies) signaling by HPK1 (show MAP4K1 Antibodies)-mediated phosphorylation, ubiquitination, and subsequent degradation of the activated BLNK

  5. CMTM7 (show CMTM7 Antibodies) functions to link sIgM and BLNK in the plasma membrane.

  6. Live cell imaging and co-immunoprecipitation experiments confirmed that both SLP65 and CIN85 (show SH3KBP1 Antibodies) are both required for the onset and progression phases of B-cell antigen receptor signal transduction.

  7. malignant transformation of Btk (show BTK Antibodies)/Slp65 double-deficient pre-B cells is independent of deregulated V(D)J recombination activity.

  8. Swip-1 (show WSB1 Antibodies) provides a membrane scaffold that is required for the Syk (show SYK Antibodies)-, SLP-65-, and PLCgamma2 (show PLCG2 Antibodies)-dependent BCR (show BCR Antibodies)-induced calcium flux.

  9. malignant transformation of Slp65(-/-) pre-B cells involves disruption of the p19(Arf (show CDKN2A Antibodies))-Mdm2 (show MDM2 Antibodies)-p53 tumor suppressor (show TP53 Antibodies) pathway

  10. The direct recruitment of BLNK to immunoglobulin alpha couples the B-cell antigen receptor to distal signaling pathways

Human B-Cell Linker (BLNK) interaction partners

  1. vesicular signaling scaffolds are required for B cell activation indicates that vesicles may deliver preassembled signaling cargo to sites of BCR (show BCR Antibodies) activation.

  2. early Ca(2 (show CA2 Antibodies)+) fluxing provides feed-forward signal amplification by promoting anchoring of the PLCgamma2 (show PLCG2 Antibodies) C2 domain to phospho-SLP65.

  3. up-regulation of BLNK is associated with RUNX1 (show RUNX1 Antibodies) mutations in cytogenetically normal acute myeloid leukemia (show BCL11A Antibodies).

  4. Live cell imaging and co-immunoprecipitation experiments confirmed that both SLP65 and CIN85 (show SH3KBP1 Antibodies) are both required for the onset and progression phases of B-cell antigen receptor signal transduction.

  5. 16 of the 34 childhood pre-B acute lymphoblastic leukaemia samples that were tested showed a complete loss or drastic reduction of SLP-65 expression

  6. The BLNK protein is present in the majority of mediastinal B cell lymphomas.

  7. In B cells SLP-65 exists in a 180 kDa complex as well as in monomeric form.

  8. V(H) gene rearrangement represents a frequent feature in B-lymphoid malignancy, which can be attributed to SLP65 deficiency in many cases.

  9. Syk (show SYK Antibodies) is required to link phosphorylated SLP-65 to Ca(2 (show CA2 Antibodies)+) mobilization.

  10. Plasmacytoid dendritic cells express a signalosome consisting of Lyn (show LYN Antibodies), Syk (show SYK Antibodies), Btk (show BTK Antibodies), Slp65 (Blnk) and PLCgamma2 (show PLCG2 Antibodies). Triggering CD303 leads to tyrosine phosphorylation of Syk (show SYK Antibodies), Slp65, PLCgamma2 (show PLCG2 Antibodies) & cytoskeletal proteins.

B-Cell Linker (BLNK) Antigen Profile

Protein Summary

This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with anti-B-Cell Linker (BLNK) Antibodies

  • B-cell linker (BLNK) antibody
  • B-cell linker (blnk) antibody
  • B-cell linker protein (blnk) antibody
  • B cell linker (Blnk) antibody
  • B-cell linker (Blnk) antibody
  • B-cell linker-like (LOC100354716) antibody
  • AGM4 antibody
  • BASH antibody
  • bca antibody
  • blnk antibody
  • BLNK-S antibody
  • Ly-57 antibody
  • LY57 antibody
  • Lyw-57 antibody
  • MGC147045 antibody
  • SLP-65 antibody
  • SLP65 antibody

Protein level used designations for anti-B-Cell Linker (BLNK) Antibodies

B-cell linker , B-cell linker protein , b-cell linker protein-like , B-cell adapter containing a SH2 domain protein , B-cell adapter containing a Src homology 2 domain protein , cytoplasmic adapter protein , lymphocyte antigen 57 , src homology 2 domain-containing leukocyte protein of 65 kDa , B cell adaptor containing SH2 domain , B cell linker protein , B-cell activation , Src homology 2 domain-containing leukocyte protein of 65 kDa , Src homology [SH2] domain-containing leukocyte protein of 65 kD , B cell linker protein BLNK , B-cell adapter SH2 domain-containing protein , SLP-65

GENE ID SPECIES
100070841 Equus caballus
405764 Danio rerio
450641 Pan troglodytes
548350 Xenopus (Silurana) tropicalis
704363 Macaca mulatta
100306798 Salmo salar
100456635 Pongo abelii
100481331 Ailuropoda melanoleuca
100593492 Nomascus leucogenys
17060 Mus musculus
29760 Homo sapiens
395733 Gallus gallus
499356 Rattus norvegicus
486814 Canis lupus familiaris
100152350 Sus scrofa
510393 Bos taurus
100712978 Cavia porcellus
101111241 Ovis aries
100354716 Oryctolagus cuniculus
Selected quality suppliers for anti-B-Cell Linker (BLNK) Antibodies
Did you look for something else?