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BCL2-Associated Athanogene 4 Proteins (BAG4)

The protein encoded by BAG4 is a member of the BAG1-related protein family. Additionally we are shipping BCL2-Associated Athanogene 4 Antibodies (112) and BCL2-Associated Athanogene 4 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
BAG4 9530 O95429
BAG4 67384 Q8CI61
Rat BAG4 BAG4 361167  
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Top BCL2-Associated Athanogene 4 Proteins at antibodies-online.com

Showing 5 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Arabidopsis thaliana His tag   1 mg Log in to see 56 to 66 Days
$2,700.50
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

BAG4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for BCL2-Associated Athanogene 4 (BAG4) Interaction Partners

Human BCL2-Associated Athanogene 4 (BAG4) interaction partners

  1. SGK1.1 regulates gene transcription upon a different set of genes some of which participate in cell survival pathways (BAG-4) and others in intracellular vesicular traffic (Brox).

  2. SODD over-expression might be correlated with the clinical classification, curative effect, and prognosis of ALL cells.

  3. MicroRNA-26a is strongly downregulated in melanoma and induces cell death through repression of silencer of death domains (SODD).

  4. Altered signaling of TNFalpha (show TNF Proteins)-TNFR1 (show TNFRSF1A Proteins) and SODD/BAG4 is responsible for radioresistance in human HT-R15 cells.

  5. SODD/BAG-4 is not only a silencer of TNFR1 (show TNFRSF1A Proteins) but also a modulator of CD95 (show FAS Proteins) activity, regulating the balance of both death-promoting and -depressing signals

  6. These data confirm that silencer of death domains (SODD) and death receptor 3 (DR3 (show TNFRSF25 Proteins)) are expressed in a regulated manner during renal transplant rejection, and identify DR3 (show TNFRSF25 Proteins) as a potential inducible mediator of tubular inflammation and injury.

  7. BAG-4 functions as a negative regulator for apobec-1 (show APOBEC1 Proteins)-mediated apoB (show APOB Proteins) mRNA editing

  8. results of analysis of the genome-wide scan data was a 20 cM region at 8p11-23 in which markers had LODs > or =1.0. Linkage and association analyses of these SNPs yield suggestive results for markers in FGFR1 (show FGFR1 Proteins) and BAG4.

  9. Vincristine induces Jurkat cell apoptosis by downregulating expression of SODD protein and priming the death receptor pathway.

Mouse (Murine) BCL2-Associated Athanogene 4 (BAG4) interaction partners

  1. Silencer of death domains (SODD) inhibits skeletal muscle and kidney enriched inositol 5-phosphatase (SKIP) and regulates phosphoinositide 3-kinase (PI3K)/Akt (show AKT1 Proteins) signaling to the actin cytoskeleton.

  2. SODD/BAG-4 is not only a silencer of TNFR1 (show TNFRSF1A Proteins) but also a modulator of CD95 (show FAS Proteins) activity, regulating the balance of both death-promoting and -depressing signals

  3. Results suggest that silencer of death domains protein (SODD) is critical for the regulation of tumor necrosis factor (show TNF Proteins) signaling.

  4. our data do not support the concept of a unique, nonredundant role of SODD for the functions of TNFR1 (show TNFRSF1A Proteins), Hsp70 (show HSP70 Proteins), and DR3 (show TNFRSF25 Proteins).

  5. BAG-4 functions as a negative regulator for apobec-1 (show APOBEC1 Proteins)-mediated apoB (show APOB Proteins) mRNA editing

  6. The proapoptotic proteins Bak (show BAK1 Proteins) (Bcl-2 (show BCL2 Proteins) antagonistic killer) and Bax (show BAX Proteins) (Bcl-2 (show BCL2 Proteins)-associated X protein) were depleted in livers from TCPOBOP-treated CAR+/+ mice.

BCL2-Associated Athanogene 4 (BAG4) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. Alternatively spliced transcript variants encoding distinct isoforms have been identified.

Gene names and symbols associated with BAG4

  • BCL2-associated athanogene 4 (BAG4)
  • BCL2-associated athanogene 4 (LOC782908)
  • BCL2-associated athanogene 4 (bag4)
  • BCL-2-associated athanogene 4 (BAG4)
  • BCL2-associated athanogene 4 (Bag4)
  • 2410112I15Rik protein
  • ATBAG4 protein
  • BAG-4 protein
  • BAG4 protein
  • BCL-2-associated athanogene 4 protein
  • fd20a04 protein
  • si:dkey-220o5.3 protein
  • SODD protein
  • wu:fd20a04 protein

Protein level used designations for BAG4

BCL2-associated athanogene 4 , BAG family molecular chaperone regulator 4 , BAG-family molecular chaperone regulator-4 , bcl-2-associated athanogene 4 , silencer of death domains , BAG-4

GENE ID SPECIES
426776 Gallus gallus
464116 Pan troglodytes
472932 Pan troglodytes
703953 Macaca mulatta
782908 Bos taurus
100001980 Danio rerio
100057730 Equus caballus
100598005 Nomascus leucogenys
824341 Arabidopsis thaliana
9530 Homo sapiens
67384 Mus musculus
361167 Rattus norvegicus
516353 Bos taurus
607954 Canis lupus familiaris
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