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BCL2-Associated Athanogene 5 Proteins (BAG5)

The protein encoded by BAG5 is a member of the BAG1-related protein family. Additionally we are shipping BAG5 Antibodies (143) and BAG5 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
BAG5 9529 Q9UL15
BAG5 70369 Q8CI32
Rat BAG5 BAG5 366734 Q5QJC9
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Top BAG5 Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,254.17
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$3,263.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

BAG5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for BCL2-Associated Athanogene 5 (BAG5) Interaction Partners

Human BCL2-Associated Athanogene 5 (BAG5) interaction partners

  1. This study showed that BAG2 (show BAG2 Proteins) (Bcl-2 (show BCL2 Proteins) associated athanogene family protein 2) and BAG5 (Bcl-2 (show BCL2 Proteins)-associated athanogene family protein 5 (show CAPS Proteins)) stabilise pathogenic ataxin3-80Q by inhibiting its ubiquitination.

  2. BAG5 protects against mitochondrial oxidative damage through regulating PINK1 (show PINK1 Proteins) degradation.

  3. BAG5 is a binding partners of LRRK2 (show LRRK2 Proteins) and part of a complex that promotes clearance of Golgi-derived vesicles through the autophagy-lysosome system.

  4. Bag5 is overexpressed in prostate cancer and plays a role in endoplamic reticulum-stress induced apoptosis. Furthermore we have identified GRP78/BiP (show HSPA5 Proteins) as a novel interaction partner of Bag5.

  5. BAG5 directly interacts with Parkin and stabilizes Parkin via the ubiquitin-mediated proteasomal pathway.

  6. A novel function for BAG5 as a modulator of CHIP E3 ubiquitin ligase (show MUL1 Proteins) activity with implications for CHIP-mediated regulation of alpha-syn oligomerization.

  7. We replicated the association of BCL2L11 (show BCL2L11 Proteins) and CASP9 (show CASP9 Proteins) with non-Hodgkin's lymphoma risk at the gene and SNP level, and identified novel associations with BCLAF1 and BAG5.

  8. Bcl-2-associated athanogene 5 (BAG5) is a negative regulator of both Hsp70 and parkin function that sensitizes dopaminergic neurons to injury-induced death.

Mouse (Murine) BCL2-Associated Athanogene 5 (BAG5) interaction partners

  1. knockdown of Bag5 exacerbated Abeta1-42-induced apoptosis.

  2. BAG5 protects against mitochondrial oxidative damage through regulating PINK1 (show PINK1 Proteins) degradation.

  3. Bcl-2-associated athanogene 5 (BAG5) is a negative regulator of both Hsp70 and parkin function that sensitizes dopaminergic neurons to injury-induced death.

BAG5 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with BAG5

  • BCL2-associated athanogene 5 (BAG5)
  • BCL2-associated athanogene 5 (bag5)
  • BCL2-associated athanogene 5 (LOC100224785)
  • BCL2-associated athanogene 5 (Bag5)
  • 1600025G07Rik protein
  • 4930405J06Rik protein
  • BAG-5 protein
  • BAG5 protein
  • zgc:114117 protein

Protein level used designations for BAG5

BCL2-associated athanogene 5 , BAG family molecular chaperone regulator 5 , BAG family molecular chaperone regulator 5-like , BAG-family molecular chaperone regulator-5 , bcl-2-associated athanogene 5 , BAG-5 , BAG-family molecular chaperone regulator-5 (BAG-5)

GENE ID SPECIES
453187 Pan troglodytes
569580 Danio rerio
100126679 Xenopus (Silurana) tropicalis
100224785 Taeniopygia guttata
100380758 Salmo salar
100433085 Pongo abelii
100581765 Nomascus leucogenys
9529 Homo sapiens
70369 Mus musculus
366734 Rattus norvegicus
480444 Canis lupus familiaris
522854 Bos taurus
423482 Gallus gallus
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