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BCLAF1 encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Additionally we are shipping and BCLAF1 Kits (1) and many more products for this protein.
Showing 10 out of 89 products:
Human Polyclonal BCLAF1 Primary Antibody for EIA, IHC (p) - ABIN950638
Sarras, Alizadeh Azami, McPherson: In search of a function for BCLAF1. in TheScientificWorldJournal 2010
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Human Polyclonal BCLAF1 Primary Antibody for IHC (p), WB - ABIN654941
Liu, Lu, Miki, Yoshida: Protein kinase C delta induces transcription of the TP53 tumor suppressor gene by controlling death-promoting factor Btf in the apoptotic response to DNA damage. in Molecular and cellular biology 2007
Show all 3 references for ABIN654941
Human Monoclonal BCLAF1 Primary Antibody for IF, WB - ABIN968645
Kasof, Goyal, White: Btf, a novel death-promoting transcriptional repressor that interacts with Bcl-2-related proteins. in Molecular and cellular biology 1999
Human Polyclonal BCLAF1 Primary Antibody for ELISA, WB - ABIN1451058
Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... in Nature 2003
SRSF10 (show SRSF10 Antibodies) is a key regulator of BCLAF1 pre-mRNA splicing and the maintenance of oncogenic features in human colon cancer cells
findings showed that FXR1P (show FXR1 Antibodies) interacts with BTF in vivo and proved that FXR1P (show FXR1 Antibodies) and BTF can co-localize mainly in the cytoplasm around the nucleus
BTF has functions distinct from TRAP150 (show THRAP3 Antibodies) in regulating the subcellular distribution of mRNAs in human cells.
BCLAF1 co-localized with gammaH2AX (show H2AFX Antibodies) foci in nuclei and stabilized the Ku70 (show XRCC6 Antibodies)/DNA-PKcs (show PRKDC Antibodies) complex therein, facilitating non-homologous end joining (NHEJ)-based DSB repair in surviving cells.
In the absence of BclAF1 neutralization, viral gene expression and replication are inhibited. These data identify two temporally and mechanistically distinct functions used by human cytomegalovirus to down-regulate a cellular antiviral protein
Sirt1 (show SIRT1 Antibodies) negatively regulates T cell activation via H3K56 deacetylation at the promoter region to inhibit transcription of Bclaf1
We replicated the association of BCL2L11 (show BCL2L11 Antibodies) and CASP9 (show CASP9 Antibodies) with non-Hodgkin's lymphoma risk at the gene and SNP level, and identified novel associations with BCLAF1 and BAG5 (show BAG5 Antibodies).
Findings indicate a role for BCLAF1 in post-transcriptional processes that impact mRNA metabolism.
Two-dimensional differential in-gel electrophoresis (2D-DIGE) revealed the differential expression of 51 proteins in response to C16-ceramide. Cell death-promoting factor Btf was found to be implicated in the apoptotic signal triggered by ceramide.
These results suggest that Btf localization is regulated by apoptotic signals, and that loss of emerin (show EMD Antibodies) binding to Btf may be relevant to muscle wasting in Emery-Dreifuss muscular dystrophy.
Bclaf1 facilitates the differentiation of early retinal precursors into retinal ganglion cells, amacrine cells, and horizontal cells rather than into cone photoreceptors.
Bclaf1 expression was found to be strongly upregulated during the saccular stage of murine embryonic lung development and was dispensable for thymocyte development.
This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
BCL2-associated transcription factor 1
, bcl-2-associated transcription factor 1
, mitochondrial fission regulator 2
, protein FAM54A