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anti-BCL2-Associated Transcription Factor 1 (BCLAF1) Antibodies

BCLAF1 encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Additionally we are shipping and BCLAF1 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BCLAF1 9774 Q9NYF8
BCLAF1 72567 Q8K019
BCLAF1 293017  
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Top anti-BCLAF1 Antibodies at antibodies-online.com

Showing 10 out of 89 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB BCLAF1 Antibody (C-term)  western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the BCLAF1 antibody detected the BCLAF1 protein (arrow). BCLAF1 antibody (C-term)  immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.  This data demonstrates the use of the BCLAF1 antibody (C-term) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB BCLAF1 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the BCLAF1 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. BCLAF1 Antibody (C-term) western blot analysis in MCF-7 cell line lysates (35µg/lane).This demonstrates the BCLAF1 antibody detected the BCLAF1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated IF, WB Western blot analysis of Btf on a Jurkat cell lysate (Human T-cell leukemia, ATCC TIB-152) . Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the mouse anti-human Btf antibody. Immunofluorescence staining of human endothelial cells. 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p), WB Human Spleen (formalin-fixed, paraffin-embedded) stained with BCLAF1 antibody ABIN296759 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IP, WB Western blot analysis of BCLAF1 expression in K562 (A), MCF7 (B), A549 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Rat Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IP, WB   0.1 mL Log in to see 6 to 8 Days
$412.50
Details

BCLAF1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-BCLAF1 Antibodies

  1. Human Polyclonal BCLAF1 Primary Antibody for EIA, IHC (p) - ABIN950638 : Sarras, Alizadeh Azami, McPherson: In search of a function for BCLAF1. in TheScientificWorldJournal 2010 (PubMed)
    Show all 3 references for ABIN950638

  2. Human Polyclonal BCLAF1 Primary Antibody for IHC (p), WB - ABIN654941 : Liu, Lu, Miki, Yoshida: Protein kinase C delta induces transcription of the TP53 tumor suppressor gene by controlling death-promoting factor Btf in the apoptotic response to DNA damage. in Molecular and cellular biology 2007 (PubMed)
    Show all 3 references for ABIN654941

  3. Human Monoclonal BCLAF1 Primary Antibody for IF, WB - ABIN968645 : Kasof, Goyal, White: Btf, a novel death-promoting transcriptional repressor that interacts with Bcl-2-related proteins. in Molecular and cellular biology 1999 (PubMed)

  4. Human Polyclonal BCLAF1 Primary Antibody for ELISA, WB - ABIN1451058 : Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... in Nature 2003 (PubMed)

More Antibodies against BCLAF1 Interaction Partners

Human BCL2-Associated Transcription Factor 1 (BCLAF1) interaction partners

  1. SRSF10 (show SRSF10 Antibodies) is a key regulator of BCLAF1 pre-mRNA splicing and the maintenance of oncogenic features in human colon cancer cells

  2. findings showed that FXR1P (show FXR1 Antibodies) interacts with BTF in vivo and proved that FXR1P (show FXR1 Antibodies) and BTF can co-localize mainly in the cytoplasm around the nucleus

  3. BTF has functions distinct from TRAP150 (show THRAP3 Antibodies) in regulating the subcellular distribution of mRNAs in human cells.

  4. BCLAF1 co-localized with gammaH2AX (show H2AFX Antibodies) foci in nuclei and stabilized the Ku70 (show XRCC6 Antibodies)/DNA-PKcs (show PRKDC Antibodies) complex therein, facilitating non-homologous end joining (NHEJ)-based DSB repair in surviving cells.

  5. In the absence of BclAF1 neutralization, viral gene expression and replication are inhibited. These data identify two temporally and mechanistically distinct functions used by human cytomegalovirus to down-regulate a cellular antiviral protein

  6. Sirt1 (show SIRT1 Antibodies) negatively regulates T cell activation via H3K56 deacetylation at the promoter region to inhibit transcription of Bclaf1

  7. We replicated the association of BCL2L11 (show BCL2L11 Antibodies) and CASP9 (show CASP9 Antibodies) with non-Hodgkin's lymphoma risk at the gene and SNP level, and identified novel associations with BCLAF1 and BAG5 (show BAG5 Antibodies).

  8. Findings indicate a role for BCLAF1 in post-transcriptional processes that impact mRNA metabolism.

  9. Two-dimensional differential in-gel electrophoresis (2D-DIGE) revealed the differential expression of 51 proteins in response to C16-ceramide. Cell death-promoting factor Btf was found to be implicated in the apoptotic signal triggered by ceramide.

  10. These results suggest that Btf localization is regulated by apoptotic signals, and that loss of emerin (show EMD Antibodies) binding to Btf may be relevant to muscle wasting in Emery-Dreifuss muscular dystrophy.

Mouse (Murine) BCL2-Associated Transcription Factor 1 (BCLAF1) interaction partners

  1. Bclaf1 facilitates the differentiation of early retinal precursors into retinal ganglion cells, amacrine cells, and horizontal cells rather than into cone photoreceptors.

  2. Sirt1 (show SIRT1 Antibodies) negatively regulates T cell activation via H3K56 deacetylation at the promoter region to inhibit transcription of Bclaf1

  3. Bclaf1 expression was found to be strongly upregulated during the saccular stage of murine embryonic lung development and was dispensable for thymocyte development.

BCLAF1 Antigen Profile

Protein Summary

This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with BCLAF1

  • BCL2-associated transcription factor 1 (BCLAF1) antibody
  • BCL2-associated transcription factor 1 (bclaf1) antibody
  • BCL2-associated transcription factor 1 (LOC100231845) antibody
  • BCL2-associated transcription factor 1 (LOC100339738) antibody
  • BCL2-associated transcription factor 1 (LOC100351429) antibody
  • BCL2-associated transcription factor 1 (Bclaf1) antibody
  • 2610102K23Rik antibody
  • 2700025J07Rik antibody
  • 2810454G14Rik antibody
  • 5730534O06Rik antibody
  • Aa2-041 antibody
  • AI450190 antibody
  • AW556225 antibody
  • BCLAF1 antibody
  • bK211L9.1 antibody
  • Btf antibody
  • DKFZp468F0113 antibody
  • Fam54a antibody
  • mKIAA0164 antibody
  • Mtfr2 antibody

Protein level used designations for BCLAF1

BCL2-associated transcription factor 1 , bcl-2-associated transcription factor 1 , mitochondrial fission regulator 2 , protein FAM54A

GENE ID SPECIES
421691 Gallus gallus
463020 Pan troglodytes
705705 Macaca mulatta
100031462 Monodelphis domestica
100144743 Xenopus (Silurana) tropicalis
100172424 Pongo abelii
100231845 Taeniopygia guttata
100339738 Oryctolagus cuniculus
100351429 Oryctolagus cuniculus
100462726 Sus scrofa
100551405 Meleagris gallopavo
100564732 Anolis carolinensis
100594410 Nomascus leucogenys
9774 Homo sapiens
72567 Mus musculus
293017 Rattus norvegicus
483999 Canis lupus familiaris
540648 Bos taurus
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