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The protein encoded by BNIPL interacts with several other proteins, such as BCL2, ARHGAP1, MIF and GFER. Additionally we are shipping BNIPL Proteins (4) and BNIPL Kits (2) and many more products for this protein.
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These results indicate the presence of two BNIP-S splicing variants as cellular regulators and that the BCH (show CHN2 Antibodies) domain of BNIP-Salpha confers a novel apoptotic function. The significance of this is discussed
interaction with cell proliferation-related proteins, MIF (show AMH Antibodies) and GFER (show GFER Antibodies)
BNIPL-2, a novel homologue of BNIP-2 (show BNIP2 Antibodies), interacts with Bcl-2 (show BCL2 Antibodies) and Cdc42GAP (show ARHGAP1 Antibodies) in apoptosis.
Data suggest that Bcl-2 (show BCL2 Antibodies)/adenovirus E1B (show BCKDHB Antibodies) 19 ku interacting protein 2-like (BNIPL-2) may regulate apoptosis through changes in the expression of genes associated with cell apoptosis, growth inhibition and cell proliferation.
p16INK4 (show CDKN2A Antibodies), IL-12 (show IL12A Antibodies), TRAIL & lymphotoxin beta (show LTB Antibodies) gene involved in growth suppression or cell apoptosis were up-regulated & PTEN (show PTEN Antibodies) was down-regulated by BNIPL-1;suggests that it might inhibit cell growth though cell cycle arrest &/or apoptotic cell death pathway(s)
The protein encoded by this gene interacts with several other proteins, such as BCL2, ARHGAP1, MIF and GFER. It may function as a bridge molecule between BCL2 and ARHGAP1/CDC42 in promoting cell death. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
, bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein