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The protein encoded by BNIPL interacts with several other proteins, such as BCL2, ARHGAP1, MIF and GFER. Additionally we are shipping BNIPL Antibodies (16) and BNIPL Proteins (4) and many more products for this protein.
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These results indicate the presence of two BNIP-S splicing variants as cellular regulators and that the BCH (show CHN2 ELISA Kits) domain of BNIP-Salpha confers a novel apoptotic function. The significance of this is discussed
interaction with cell proliferation-related proteins, MIF (show AMH ELISA Kits) and GFER (show GFER ELISA Kits)
BNIPL-2, a novel homologue of BNIP-2 (show BNIP2 ELISA Kits), interacts with Bcl-2 (show BCL2 ELISA Kits) and Cdc42GAP (show ARHGAP1 ELISA Kits) in apoptosis.
Data suggest that Bcl-2 (show BCL2 ELISA Kits)/adenovirus E1B (show BCKDHB ELISA Kits) 19 ku interacting protein 2-like (BNIPL-2) may regulate apoptosis through changes in the expression of genes associated with cell apoptosis, growth inhibition and cell proliferation.
p16INK4, IL-12 (show IL12A ELISA Kits), TRAIL & lymphotoxin beta (show LTB ELISA Kits) gene involved in growth suppression or cell apoptosis were up-regulated & PTEN was down-regulated by BNIPL-1;suggests that it might inhibit cell growth though cell cycle arrest &/or apoptotic cell death pathway(s)
The protein encoded by this gene interacts with several other proteins, such as BCL2, ARHGAP1, MIF and GFER. It may function as a bridge molecule between BCL2 and ARHGAP1/CDC42 in promoting cell death. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
, bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein