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anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) Antibodies

BNIP3 is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. Additionally we are shipping BNIP3 Kits (6) and BNIP3 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BNIP3 664 Q12983
BNIP3 12176 O55003
BNIP3 84480  
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Top anti-BNIP3 Antibodies at antibodies-online.com

Showing 10 out of 157 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB The anti-NIP3 BH3 domain Pab (ABIN388117) is used in Western blot to detect NIP3 BH3 in Ramos cell lysate (lane 1) and in mouse brain tissue lysate (lane 2). Freshly isolated mouse hepatocytes plated on coverslips (2 x105 cells/22-mm glass coverslip) were cultured under normoxic conditions for 6 hr. The cells were then fixed in 2% paraformaldehyde in PBS for 1 hr, and processed for confocal immunofluorescence (red: F-actin, blue: ATP-synthase, green: BNIP3). Fluorescence labeling of BNIP3 accomplished with anti-BNIP3 antibody ABIN388117. Data courtesy of Ruben Zamora, University of Pittsburgh. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB Immunohistochemical analysis of paraffin embedded cancer sections, staining in nucleus, DAB chromogenic reaction Western blot analysis of rat thymus tissue lysis using NIP3 antibody 0.1 mg Log in to see 6 to 8 Days
$313.50
Details
Human Rabbit Un-conjugated WB Anti-BNIP3 antibody, Western blotting All lanes: Anti BNIP3  at 0.5ug/ml Lane 1: HELA Whole Cell Lysate at 40ug Lane 2: MM231Whole Cell Lysate at 40ug Predicted bind size: 22KD Observed bind size: 30KD 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of BNIP3 expression in HeLa (A), MCF7 (B), SHSY5Y (C), Ramos (D) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated IF, IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemistry analyzes of BNIP-3 antibody in paraffin-embedded human brain tissue. Western blot (WB) analysis of BNIP-3 antibody in extracts from K562cells. 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB 400 μL Log in to see 6 Days
$457.14
Details
Human Mouse Un-conjugated IHC (p), IP, ELISA, WB Human Prostate (formalin-fixed, paraffin-embedded) stained with BNIP3 antibody ABIN461995 at 10 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with BNIP3 antibody ABIN461995 at 10 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. 50 μL Log in to see 8 to 10 Days
$595.83
Details

BNIP3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-BNIP3 Antibodies

  1. Human Polyclonal BNIP3 Primary Antibody for IF, IHC (p) - ABIN388117 : Kothari, Cizeau, McMillan-Ward, Israels, Bailes, Ens, Kirshenbaum, Gibson: BNIP3 plays a role in hypoxic cell death in human epithelial cells that is inhibited by growth factors EGF and IGF. in Oncogene 2003 (PubMed)
    Show all 5 references for ABIN388117

  2. Human Polyclonal BNIP3 Primary Antibody for EIA, IHC (p) - ABIN356828 : Zhang, Heim, Meyhack: Novel BNIP1 variants and their interaction with BCL2 family members. in FEBS letters 1999 (PubMed)
    Show all 2 references for ABIN356828

More Antibodies against BNIP3 Interaction Partners

Human BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) interaction partners

  1. Results suggest that changes in mitochondrial morphology and transmembrane potential, induced by mutant htt (show HTT Antibodies) protein, are dependent and linked to BNip3 and not to Bax (show BAX Antibodies)/Bak (show BAK1 Antibodies) activation.

  2. Hypoxia-induced autophagy contributes to the invasion of salivary adenoid cystic carcinoma through the HIF-1alpha (show HIF1A Antibodies)/BNIP3 signaling pathway.

  3. The data indicated that BNIP3 plays a vital role in the tumorigenesis of adenoid cystic carcinoma and could be a new target for gene therapy of adenoid cystic carcinoma.

  4. BNIP3 deletion can be used as a prognostic (show HIF1A Antibodies)marker of tumor progression to metastasis in human triple-negative breast cancer

  5. BNIP3 expression was found to be regulated by Sp3 (show SP3 Antibodies) in prostate cancer.

  6. phosphorylation of these C-terminal BNIP3 residues blocks cell death without preventing autophagy, providing evidence that the two functional roles of BNIP3 can be regulated independently

  7. Bnip3 dual-functionality and crosstalk between mitophagy and apoptosis pathways is presented here.

  8. these findings revealed that silibinin induced autophagic cell death through ROS (show ROS1 Antibodies)-dependent mitochondrial dysfunction and ATP depletion involving BNIP3 in MCF7 cells.

  9. The findings of the present study reveal a novel survival pathway that functionally couples the unique glycolytic phenotype in cancer cells to hypoxia resistance via a PDK2 (show PDK2 Antibodies)-dependent mechanism that switches Bnip3 from cell death to survival.

  10. Mevalonate depletion through HMG-CoA reductase (show HMGCR Antibodies) inhibition impairs the viability of primary human mesenchymal stells via NF-kappaB (show NFKB1 Antibodies)/Bnip3 signaling.

Mouse (Murine) BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) interaction partners

  1. Data show that TGFbeta (show TGFB1 Antibodies)-activated kinase-1 (TAK1 (show NR2C2 Antibodies)) activated nuclear factor of activated T-cells (NFAT (show NFATC1 Antibodies))/NF-kappa B (NFkappaB (show NFKB1 Antibodies)), downregulated BCL2-adenovirus E1B interacting protein 3 (Bnip3), and inhibited cardiac cell death.

  2. propose that BNIP3 acts as a brake on HIF-1 (show HIF1A Antibodies) activity serving to increase rates of mitophagy in response to hypoxia and to limit production of damaging ROS (show ROS1 Antibodies) that would further amplify HIF-1 (show HIF1A Antibodies) expression and promote tumor progression to metastasis

  3. Results suggest that Bnip3 regulates cardiac gene expression and perhaps myocyte morphology by activating nuclear p300 acetyltransferase and hyperacetylating histones and its selective transcription factors.

  4. Bnip3 dual-functionality and crosstalk between mitophagy and apoptosis pathways is presented here.

  5. regulates mitophagy during hypoxia, whereas NIX (show BNIP3L Antibodies) is required for mitophagy during development of the erythroid lineage.

  6. BNIP3 primarily regulates basal level of mitophagy in physiological conditions, whereas BNIP3 exclusively activates excessive mitophagy leading to cell death.

  7. Bnip3 generation, mediated by PARP1 (show PARP1 Antibodies), causes mitochondrial damage and neuron death.

  8. Suggest pro-tumorigenic role of BNIP3 driving melanoma cell's aggressive features, like migration and vasculogenic mimicry.

  9. BNIP3 has a protective effect against UVB-induced apoptosis in keratinocytes

  10. The BNIP3 cell death pathway may be a new target for protecting oligodendrocytes from death after stroke

BNIP3 Antigen Profile

Protein Summary

This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. This protein contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein encoded by this gene is known to induce apoptosis, even in the presence of BCL2.

Gene names and symbols associated with BNIP3

  • BCL2/adenovirus E1B 19kDa interacting protein 3 (BNIP3) antibody
  • BCL2/adenovirus E1B interacting protein 3 (Bnip3) antibody
  • Nip3 antibody

Protein level used designations for BNIP3

BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 , BCL2/adenovirus E1B 19kD-interacting protein 3 , BCL2/adenovirus E1B 19 kDa-interacting protein 1, NIP3 , BCL2/adenovirus E1B 19kDa-interacting protein 1, NIP3 , BCL2/adenovirus E1B interacting protein 1, NIP3 , BCL2/adenovirus E1B 19 kDa-interacting protein 3

GENE ID SPECIES
664 Homo sapiens
423971 Gallus gallus
607408 Canis lupus familiaris
615342 Bos taurus
12176 Mus musculus
84480 Rattus norvegicus
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