BCL2-Associated Athanogene Proteins (BAG1)

The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. Additionally we are shipping BAG1 Antibodies (124) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
BAG1 573 Q99933
BAG1 297994 B0K019
BAG1 12017 Q60739
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Top BAG1 Proteins at antibodies-online.com

Showing 9 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 15 to 19 Days
Yeast Caenorhabditis elegans His tag   1 mg Log in to see 60 to 71 Days
Yeast Arabidopsis thaliana His tag   1 mg Log in to see 60 to 71 Days
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   1 mg Log in to see 2 to 3 Days
HOST_Escherichia coli (E. coli) Human GST tag   50 μg Log in to see 10 to 12 Days

BAG1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
Rat (Rattus)

Mouse (Murine)

Top referenced BAG1 Proteins

  1. Human BAG1 Protein expressed in Escherichia coli (E. coli) - ABIN666963 : Wang, Takayama, Rapp, Reed: Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1. in Proceedings of the National Academy of Sciences of the United States of America 1996 (PubMed)
    Show all 2 references for 666963

  2. Human BAG1 Protein expressed in Wheat germ - ABIN1346360 : Chun, Gacad, Nguyen, Hewison, Adams: Co-chaperone potentiation of vitamin D receptor-mediated transactivation: a role for Bcl2-associated athanogene-1 as an intracellular-binding protein for 1,25-dihydroxyvitamin D3. in Journal of molecular endocrinology 2007 (PubMed)

More Proteins for BCL2-Associated Athanogene (BAG1) Interaction Partners

Human BCL2-Associated Athanogene (BAG1) interaction partners

  1. BAG-4/SODD (show BAG4 Proteins), HSP70 (show HSP70 Proteins), and HSP90 (show HSP90 Proteins) are potential prognostic markers in node-negative breast carcinoma that merit further research.

  2. interaction with Bag1 then shifts hERG (show KCNH2 Proteins) degradation to the membrane-anchored E3 ligase TRC8 (show RNF139 Proteins) and its E2-conjugating enzyme Ube2g2 (show UBE2G2 Proteins), as determined by siRNA screening

  3. These results suggest that Bag1 and Bag3 (show BAG3 Proteins) control the stability of the Hsc70 (show HSPA8 Proteins)-client complex using at least two distinct protein-protein contacts, providing a previously under-appreciated layer of molecular regulation in the human Hsc70 (show HSPA8 Proteins) system.

  4. Taken together, these data indicate that Bag-1 up-regulation is required to maintain apoptosis resistance in human cytomegalovirus-infected cells.

  5. the combined effects of BAG-1 and XPD (show ERCC2 Proteins) polymorphisms on chemotherapy sensitivity and survival in patients with advanced non-small-cell lung cancer, which might be the important predictive markers for platinum-based chemotherapy efficacy.

  6. Bag-1 indirectly affects cell survival through c-Myc (show MYC Proteins) activated signalling that causes elevation of ornithine decarboxylase (show ODC1 Proteins) levels, leading to an increase of the polyamine content.

  7. Overexpression of miR (show MLXIP Proteins)-138 inhibited cell proliferation by directly suppressing the expression of Bag-1.

  8. The expression of BAG-1 was upregulated in chronic non-eosinophilic rhinosinusitis.

  9. BAG-1 expression was high in esophageal carcinoma tissues compared to normal esophagus. After Eca109 cells were transfected with BAG-1-siRNA, the proliferation and invasive capabilities of the cells were decreased while the apoptosis rate was enhanced.

  10. BAG-1M mediates Hsp70 (show HSP70 Proteins) inhibition downstream of NF-kappaB (show NFKB1 Proteins).

Mouse (Murine) BCL2-Associated Athanogene (BAG1) interaction partners

  1. The BAG-1 stabilizes F508del-CFTR by direct binding, probably competing out ubiquitin to partially avoid its proteasomal degradation.

  2. The membrane form of heparin binding EGF-like growth factor (show HBEGF Proteins) (ProHB-EGF (show EGF Proteins)) is most likely able to trigger the nuclear translocation of BAG-1 in keeping its level high.

  3. Hemoxygenase (show HMOX1 Proteins) 1 deficiency provoked diminished Bag-1 level upon LPS (show TLR4 Proteins) treatment

  4. this study first reported the solution structure of mBAG-1 (show LRRC4 Proteins)-UBH and the growth factor precursor-interacting motif on the protein.

  5. Bag-1 proteins function as regulators of the action of selective transcription factors.

  6. during development of mouse autopods, BAG-1 expression is downregulated upon the initiation of interdigital apoptosis (BAG-1)

  7. Bag1 is a regulator and marker of neuronal differentiation

  8. BAG1 displays potent neuroprotective activity in vivo against stroke.

  9. Since, BAG-1 is essential for cell survival, its association with tNhtt aggregates might disrupt its normal function and thereby promote polyglutamine-expanded tNhtt-induced cell death.

  10. Bag1 is essential for differentiation and survival of hematopoietic and neuronal cells.

BAG1 Protein Profile

Protein Summary

The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.

Gene names and symbols associated with BAG1

  • bcl2-associated athanogene (Smp_005900)
  • bcl2-associated athanogene (Smp_031560)
  • BCL2-associated athanogene (LOC100345469)
  • BCL-2-associated athanogene 1 (BAG1)
  • BCL2-associated athanogene (BAG1)
  • BCL2-associated athanogene (Bag1)
  • BCL2-associated athanogene 1 (Bag1)
  • Protein BAG-1 (bag-1)
  • ATBAG1 protein
  • Bag-1 protein
  • BCL-2-associated athanogene 1 protein
  • HAP protein
  • MSG15.15 protein
  • MSG15_15 protein
  • Rap46 protein

Protein level used designations for BAG1

bcl2-associated athanogene , BCL2-associated athanogene , BAG family molecular chaperone regulator 1 , Bcl-2 associating athanogene-1 protein , Bcl-2-binding protein , glucocortoid receptor-associated protein RAP46 , receptor-associated protein, 46-KD , bcl-2-associated athanogene 1

8342092 Schistosoma mansoni
8350429 Schistosoma mansoni
100345469 Oryctolagus cuniculus
835281 Arabidopsis thaliana
573 Homo sapiens
297994 Rattus norvegicus
781741 Bos taurus
611781 Canis lupus familiaris
12017 Mus musculus
172373 Caenorhabditis elegans
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