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BNIP3L is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. Additionally we are shipping BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like Proteins (4) and BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like Kits (1) and many more products for this protein.
Showing 10 out of 111 products:
Human Polyclonal BNIP3L Primary Antibody for WB - ABIN264993
Matsushima, Fujiwara, Takahashi, Minaguchi, Eguchi, Tsujimoto, Suzumori, Nakamura: Isolation, mapping, and functional analysis of a novel human cDNA (BNIP3L) encoding a protein homologous to human NIP3. in Genes, chromosomes & cancer 1998
Show all 6 references for ABIN264993
Human Polyclonal BNIP3L Primary Antibody for EIA, FACS - ABIN950671
Novak, Kirkin, McEwan, Zhang, Wild, Rozenknop, Rogov, Löhr, Popovic, Occhipinti, Reichert, Terzic, Dötsch, Ney, Dikic: Nix is a selective autophagy receptor for mitochondrial clearance. in EMBO reports 2009
Show all 5 references for ABIN950671
Human Polyclonal BNIP3L Primary Antibody for IHC, IHC (p) - ABIN4285004
Li, Zhang, Zhuang, Chen, Chen, Tian, Wu, Li, Wang, Zhang, Chen, Li, Zhao, Sui, Hu, Feng: MicroRNA-137 is a novel hypoxia-responsive microRNA that inhibits mitophagy via regulation of two mitophagy receptors FUNDC1 and NIX. in The Journal of biological chemistry 2014
Show all 2 references for ABIN4285004
Human Monoclonal BNIP3L Primary Antibody for IF, ELISA - ABIN560088
Nakamura, Kitamura, Shinogi, Yoshida, Goda, Murai, Kamino, Arakawa: BNIP3 and NIX mediate Mieap-induced accumulation of lysosomal proteins within mitochondria. in PLoS ONE 2012
Show all 2 references for ABIN560088
Human Polyclonal BNIP3L Primary Antibody for IHC (p), IHC - ABIN269357
Passer, Nancy-Portebois, Amzallag, Prieur, Cans, Roborel de Climens, Fiucci, Bouvard, Tuynder, Susini, Morchoisne, Crible, Lespagnol, Dausset, Oren, Amson, Telerman: The p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinase. in Proceedings of the National Academy of Sciences of the United States of America 2003
Human Polyclonal BNIP3L Primary Antibody for FACS, IF - ABIN655731
Wang, McDonnell, Hebbring, Cunningham, St Sauver, Cerhan, Isaya, Schaid, Thibodeau: Polymorphisms in mitochondrial genes and prostate cancer risk. in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008
p75(NTR (show NGFR Antibodies)) and NIX may play critical roles in intracerebral hemorrhage-induced neuronal apoptosis in vitro and in vivo.
Data suggest that targeting BNIP3L protein in wild-type p53 tumor suppressor (show TP53 Antibodies) colon cancer cells is an anticancer strategy activating iron depletion signaling and the mitophagy-related cell death pathway.
regulates mitophagy during hypoxia, whereas NIX is required for mitophagy during development of the erythroid lineage.
Nix protein positively regulates NF-kappaB (show NFKB1 Antibodies) activation in gliomas
The physical interaction of Mieap (show SPATA18 Antibodies), BNIP3 (show BNIP3 Antibodies) and NIX at the mitochondrial outer membrane may play a critical role in the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix.
mitochondrial ROS (show ROS1 Antibodies) and NIX are essential factors for Mieap (show SPATA18 Antibodies)-induced accumulation of lysosome-like organelles within mitochondria
Nix functions as an autophagy receptor, which mediates mitochondrial clearance after mitochondrial damage and during erythrocyte differentiation
NIX binds to TSAP6 (show STEAP3 Antibodies) in tumor cells and has a role in apoptosis
The proapoptotic factor Nix is a highly regulated effector of growth during terminal erythroid maturation.
Bnip3L, capable of attenuating tumorigenicity, mediates p53 (show TP53 Antibodies)-dependent apoptosis under hypoxia.
Bnip3L and caspase-12 (show CASP12 Antibodies) identified by the PCR arrays at both catagen stages were additionally localized using immunofluorescence and were reported in physiological hair development for the first time.
our study demonstrates that BNIP3L, as a substrate of PARK2 (show PARK2 Antibodies), promotes mitophagy in the PINK1 (show PINK1 Antibodies)/PARK2 (show PARK2 Antibodies) pathway associated with PD pathogenesis.
Suggest Nix is a novel mediator of norepinephrine-induced fibrosis.
MicroRNA-137 has a role in inhibiting mitophagy via regulation of two mitophagy receptors FUNDC1 (show FUNDC1 Antibodies) and NIX
-stimulated cytoplasmic-nuclear shuttling of the alternately spliced non-mitochondrial Nix isoform and uncover a role for sNix as a modulator of TNFalpha/NFkappaB-stimulated cardiac gene expression
BNIP3L activity localizes to a small region in its cytoplasmic domain, the minimal essential region (MER (show ERH Antibodies)).
These results establish Nix as a critical mediator of beta cell apoptosis and programmed necrosis in Pdx1 (show PDX1 Antibodies)-deficient diabetes.
molecular events responsible for the different phases of mitophagy and placed Nix upstream of the events
Mitochondrial Nix activates Bax (show BAX Antibodies)/Bak (show BAK1 Antibodies)- and caspase (show CASP3 Antibodies)-dependent apoptosis, whereas ER-Nix activates Bax (show BAX Antibodies)/Bak (show BAK1 Antibodies)-independent, MPTP (show PTPN2 Antibodies)-dependent necrosis.
This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. This protein counteracts the apoptotic inducer BNIP3 and may play a role in tumor suppression.
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A
, BCL2/adenovirus E1B 19-kd protein-interacting protein 3a
, NIP3-like protein X
, adenovirus E1B19k-binding protein B5
, BCL2/adenovirus E1B 19kD-interacting protein 3-like
, BCL2/adenovirus E1B 19 kDa-interacting protein 3-like
, BCL2/adenovirus E1B 19kDa-interacting protein 3-like