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The protein encoded by BCORL1 is a transcriptional corepressor that is found tethered to promoter regions by DNA-binding proteins. Additionally we are shipping BCORL1 Antibodies (24) and many more products for this protein.
Studied the clinical significance of BCORL1 and its role in the metastasis of HCC (show FAM126A ELISA Kits).
BCORL1 knockdown up-regulates E-cadherin (show CDH1 ELISA Kits) expression and subsequently inhibits cell migration and invasion of lung cancer cells.
study concluded that in pediatric acute myeloid leukemia (show BCL11A ELISA Kits), BCOR (show BCOR ELISA Kits) and BCORL1 mutations rarely occur
genetic association study in population in Italy: Data suggest BCORL1 mutations/single nucleotide polymorphisms are not associated with leukemic transformation of chronic myeloproliferative neoplasms (MPN (show PRSS27 ELISA Kits)) into acute myeloid leukemia (show BCL11A ELISA Kits) (AML (show RUNX1 ELISA Kits)). [LETTER]
Data indicate that sequencing of BCOR (show BCOR ELISA Kits) and related BCORL1 genes in a cohort of 354 myelodysplastic syndromes (MDS (show PAFAH1B1 ELISA Kits)) patients identified 4.2% and 0.8% of mutations respectively.
BCORL1 by genetic criteria is a novel candidate tumor suppressor gene, joining the growing list of genes recurrently mutated in acute myelogenous leukemia.
Dysregulated BCoR-L1 expression is associated with breast cancer
The protein encoded by this gene is a transcriptional corepressor that is found tethered to promoter regions by DNA-binding proteins. The encoded protein can interact with several different class II histone deacetylases to repress transcription. Two transcript variants encoding different isoforms have been found for this gene.
BCL6 corepressor-like 1
, BCL6 co-repressor-like 1
, BCL-6 corepressor-like protein 1
, BCoR-like protein 1