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BRSK1 Proteins

(BR Serine/threonine Kinase 1 (BRSK1))

Serine/threonine-protein kinase that plays a key role in polarization of neurons and centrosome duplication. Phosphorylates CDC25B, CDC25C, MAPT/TAU, RIMS1, TUBG1, TUBG2 and WEE1. Following phosphorylation and activation by STK11/LKB1, acts as a key regulator of polarization of cortical neurons, probably by mediating phosphorylation of microtubule-associated proteins such as MAPT/TAU at 'Ser-573'. Also regulates neuron polarization by mediating phosphorylation of WEE1 at 'Ser-642' in post-mitotic neurons, leading to down-regulate WEE1 activity in polarized neurons. Also acts as a positive regulator of centrosome duplication by mediating phosphorylation of gamma-tubulin (TUBG1 and TUBG2) at 'Ser-131', leading to translocation of gamma-tubulin and its associated proteins to the centrosome. Involved in the UV- induced DNA damage checkpoint response, probably by inhibiting CDK1 activity through phosphorylation and activation of WEE1, and inhibition of CDC25B and CDC25C (By similarity). In neurons, localizes to synaptic vesicles and plays a role in neurotransmitter release, possibly by phosphorylating RIMS1.

recommended

BRSK1 Protein (AA 1-778) (GST tag) (ABIN5570636)

BRSK1 Origin: Human Host: Insect cells (Sf21) Recombinant SDS, Func Active

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recommended

BRSK1 Protein (AA 289-380) (GST tag) (ABIN1346887)

BRSK1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP

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recommended

BRSK1 Protein (AA 1-778) (Strep Tag) (ABIN3090446)

Crystallography grade BRSK1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS

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BRSK1 Proteins by Grade

Find BRSK1 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

BRSK1 Proteins by Origin

Find BRSK1 Proteins for a variety of species such as anti-Human BRSK1, anti-Mouse BRSK1, anti-Rat BRSK1. The species listed below are among those available. Click on a link to go to the corresponding products.

BRSK1 Proteins by Source

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BRSK1 Proteins by Protein Type

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BRSK1 Proteins by Application

Find BRSK1 Proteins validated for a specific application such as ELISA, SDS, WB, Func. Some of the available applications are listed below. Click on a link to go to the corresponding products.

BRSK1 Proteins by Biological Activity

Find BRSK1 Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular BRSK1 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

BRSK1 Protein (AA 1-778) (GST tag)

Reactivity Human

Source Insect cells (Sf21)

Validations

Cat. No. ABIN5570636

Quantity 5 μg

Datasheet Datasheet

BRSK1 Protein (AA 289-380) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1346887

Quantity 10 μg

Datasheet Datasheet

BRSK1 Protein (AA 1-778) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3090446

Quantity 1 mg

Datasheet Datasheet

BRSK1 Protein (AA 1-778) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3135216

Quantity 1 mg

Datasheet Datasheet

BRSK1 Protein (GST tag)

Reactivity Mouse

Source Insect Cells

Validations

Cat. No. ABIN5509205

Quantity 10 μg

Datasheet Datasheet

BRSK1 Protein (AA 1-778) (His tag)

Reactivity Rat

Source Yeast

Validations

Cat. No. ABIN1670475

Quantity 1 mg

Datasheet Datasheet

Aliases for BRSK1 Proteins

BR serine/threonine kinase 1 (BRSK1) Proteins
BR serine/threonine kinase 1 (Brsk1) Proteins
BRSK1 Proteins
Gm1100 Proteins
hSAD1 Proteins
RGD1563268 Proteins
SAD-B Proteins
Sad-b Proteins
SADB Proteins

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BRSK1 Proteins by Grade

BRSK1 Proteins by Origin

BRSK1 Proteins by Source

BRSK1 Proteins by Protein Type

BRSK1 Proteins by Application

BRSK1 Proteins by Biological Activity

Popular BRSK1 Proteins

Aliases for BRSK1 Proteins

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