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anti-BR serine/threonine Kinase 2 (BRSK2) Antibodies

Serine/threonine-protein kinase that plays a key role in polarization of neurons. Additionally we are shipping BR serine/threonine Kinase 2 Kits (7) and BR serine/threonine Kinase 2 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BRSK2 9024 Q8IWQ3
BRSK2 75770 Q69Z98
BRSK2 293631  
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Top anti-BR serine/threonine Kinase 2 Antibodies at antibodies-online.com

Showing 10 out of 71 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of BRSK2 in human brain tissue with BRSK2 antibody at 5 μg/ml. Western blot analysis of BRSK2 in human brain tissue lysate with AP30168PU-N BRSK2 antibody at (A) 0.5, (B) 1 and (C) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$221.76
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-STK29 Pab(ABIN391285) in HL60 cell line lysate (35 µg/lane). STK29(arrow) was detected using the purified polyclonal antibody (1:60 dilution). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Rabbit Un-conjugated WB Mouse Brsk2 Antibody (Center)  western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the Brsk2 antibody detected the Brsk2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IP, WB   100 μL Log in to see 8 to 10 Days
$683.83
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 15 to 19 Days
$455.07
Details
Human Goat Un-conjugated ELISA   100 μg Log in to see 8 to 10 Days
$419.83
Details
Mouse Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Goat Un-conjugated ELISA, WB   0.1 mg Log in to see 2 to 3 Days
$433.13
Details

BRSK2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-BR serine/threonine Kinase 2 Antibodies

  1. Human Polyclonal BRSK2 Primary Antibody for EIA, IHC (p) - ABIN499503 : Sabater, Gómez-Choco, Saiz, Graus: BR serine/threonine kinase 2: a new autoantigen in paraneoplastic limbic encephalitis. in Journal of neuroimmunology 2005 (PubMed)
    Show all 4 references for ABIN499503

  2. Human Polyclonal BRSK2 Primary Antibody for IHC, ELISA - ABIN1001943 : Lizcano, Göransson, Toth, Deak, Morrice, Boudeau, Hawley, Udd, Mäkelä, Hardie, Alessi: LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1. in The EMBO journal 2004 (PubMed)
    Show all 4 references for ABIN1001943

  3. Human Polyclonal BRSK2 Primary Antibody for ELISA, WB - ABIN185503 : Kishi, Pan, Crump, Sanes: Mammalian SAD kinases are required for neuronal polarization. in Science (New York, N.Y.) 2005 (PubMed)

More Antibodies against BR serine/threonine Kinase 2 Interaction Partners

Human BR serine/threonine Kinase 2 (BRSK2) interaction partners

  1. SAD-A and AMPK (show PRKAA1 Antibodies) kinases are regulators of mTORC1 signaling in the pancreatic beta-cells.

  2. BRSK2 interacted with VCP/p97 (show vcp Antibodies) via three of the four functional domains of VCP/p97 (show vcp Antibodies). Immunofluorescence demonstrated that BRSK2 and VCP/p97 (show vcp Antibodies) were co-localized and also that knockdown of endogenous BRSK2 induced increased levels of CD3delta (show CD3D Antibodies).

  3. Anaphase-promoting complex/cyclosome-Cdh1 (show CDH1 Antibodies), rather than Cdc20 (show CDC20 Antibodies), promotes the degradation of BRSK2 in vivo.

  4. a novel function of BRSK2 in the regulation of GSIS in beta-cells via a PCTAIRE1 (show CDK16 Antibodies)-dependent mechanism and suggest that BRSK2 is an attractive target for developing novel diabetic drugs.

  5. these findings demonstrate ER stress may reduce BRSK2 protein and change BRSK2 subcellular localization, which in turn alleviate ER stress-induced apoptosis.

  6. these findings provide a novel regulatory mechanism of BRSK2 through direct interaction with Jab1 (show COPS5 Antibodies).

  7. BRSK2 is up-regulated in pancreatic ductal adenocarcinoma.

  8. BRSK2 may be an autoantigen involved in the pathogenesis of small-cell lung cancer-associated limbic encephalitis.

  9. we identified cAMP-dependent protein kinase A (PKA) as another upstream kinase of BRSK2, which can phosphorylate BRSK2 at Thr260. Kinase activity of BRSK2 can be increased through phosphorylation by PKA.

  10. protein phosphatase 2C (show PDP Antibodies) is a likely candidate for catalyzing the dephosphorylation and inactivation of BRSK1 (show BRSK1 Antibodies)/2.

Mouse (Murine) BR serine/threonine Kinase 2 (BRSK2) interaction partners

  1. SAD-A and AMPK (show PRKAA1 Antibodies) kinases are regulators of mTORC1 signaling in the pancreatic beta-cells.

  2. SAD-A and SAD-B (show BRSK1 Antibodies) kinases have multiple, sequential roles in axonal differentiation

  3. SAD-A kinase controls islet beta-cell size and function as a mediator of mTORC1 signaling.

  4. SAD-A kinase is a pancreas-specific mediator of incretin response in islet beta cells.

  5. a novel function of BRSK2 in the regulation of GSIS in beta-cells via a PCTAIRE1 (show CDK16 Antibodies)-dependent mechanism and suggest that BRSK2 is an attractive target for developing novel diabetic drugs.

  6. a critical role of SAD-A in the activation of PAK1 (show PAK1 Antibodies) during the onset of insulin (show INS Antibodies) exocytosis.

  7. The regulation of Wee1 (show WEE1 Antibodies) by SadA and SadB (show BRSK1 Antibodies) kinases is essential for the differentiation of polarized neurons.

  8. results show that SAD-A and SAD-B (show BRSK1 Antibodies), mammalian orthologs of a kinase needed for presynaptic differentiation in Caenorhabditis elegans, are required for neuronal polarization.

  9. Once activated, LKB1 (show STK11 Antibodies) phosphorylates and thereby activates SAD-A and SAD-B (show BRSK1 Antibodies) kinases, which are also required for neuronal polarization in the cerebral cortex.

BR serine/threonine Kinase 2 (BRSK2) Antigen Profile

Protein Summary

Serine/threonine-protein kinase that plays a key role in polarization of neurons. Phosphorylates MAPT/TAU and WEE1. Following phosphorylation and activation by STK11/LKB1, acts as a key regulator of polarization of cortical neurons, probably by mediating phosphorylation of microtubule-associated proteins such as MAPT/TAU at 'Ser-554'. Also regulates neuron polarization by mediating phosphorylation of WEE1 at 'Ser-642' in post-mitotic neurons, leading to down-regulate WEE1 activity in polarized neurons.

Gene names and symbols associated with BRSK2

  • BR serine/threonine kinase 2 (BRSK2) antibody
  • BR serine/threonine kinase 2 (Brsk2) antibody
  • 4833424K13Rik antibody
  • BRSK2 antibody
  • C11orf7 antibody
  • PEN11B antibody
  • SAD-A antibody
  • SAD1 antibody
  • SADA antibody
  • STK29 antibody

Protein level used designations for BRSK2

BR serine/threonine-protein kinase 2 , BR serine/threonine kinase 2 , BR serine/threonine-protein kinase 2-like , brain-selective kinase 2 , brain-specific serine/threonine-protein kinase 2 , protein kinase SAD1B , serine/threonine-protein kinase 29 , serine/threonine-protein kinase BRSK2 , serine/threonine-protein kinase SAD-A , brain serine/threonine kinase 2

GENE ID SPECIES
423098 Gallus gallus
535868 Bos taurus
744454 Pan troglodytes
746226 Pan troglodytes
100395256 Callithrix jacchus
100429659 Macaca mulatta
100443903 Pongo abelii
9024 Homo sapiens
75770 Mus musculus
483658 Canis lupus familiaris
293631 Rattus norvegicus
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