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The protein encoded by BRAP was identified by its ability to bind to the nuclear localization signal of BRCA1 and other proteins. Additionally we are shipping BRAP Antibodies (43) and BRAP Proteins (4) and many more products for this protein.
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Expression of BRAP is increased in esophageal squamous cell carcinoma samples compared with non-tumor esophageal tissues; increased expression correlates with reduced patient survival time and promotes metastasis of xenograft tumors in mice.
that BRAP plays an important role in airway inflammation and its overexpression may regulate NE-induced MUC5AC hypersecretion in HBE16 cells via the EGFR (show EGFR ELISA Kits)/ERK (show EPHB2 ELISA Kits)/NF-kappaB (show NFKB1 ELISA Kits) signaling pathway
Together the results indicate for the first time that BRAP2 may play an important NRNI role in germ cells of the testis, with an additional, scaffold/structural role in mature spermatozoa.
BRAP gene may confer vulnerability for schizophrenia in Han Chinese population.
ectopic expression of BRAP2 inhibits nuclear localization of HMG20A (show HMG20A ELISA Kits) and NuMA1 (show NUMA1 ELISA Kits), and prevents nuclear envelope accumulation of SYNE2 (show SYNE2 ELISA Kits).
genetic association studies in population of Chinese Han young adults in Beijing: Data suggest that 2 SNPs in BRAP (rs11066001; rs3782886) are associated with decreased risk of metabolic syndrome in this population.
BAP1 (show RNF2 ELISA Kits) expression closely correlates with age, clinical stage, pathologic differentiation and histological type in colorectal cancer (CRC (show CALR ELISA Kits)). BAP1 (show RNF2 ELISA Kits) may serve as a novel prognostic biomarker for CRC (show CALR ELISA Kits).
Brap2 regulates temporal control of NF-kappaB (show NFKB1 ELISA Kits) localization mediated by inflammatory response.
The BRAP polymorphism may not play an important role in ischemic stroke in the Taiwanese population.
The dominant effect of prolonged USP15 (show USP15 ELISA Kits) depletion upon signal amplitude is due to a decrease in CRAF (show RAF1 ELISA Kits) levels while allowing for the possibility that USP15 (show USP15 ELISA Kits) may also function to dampen MAPK (show MAPK1 ELISA Kits) signaling through direct stabilization of BRAP.
A molecular complex composed of Nde1, Lis1 (show PAFAH1B1 ELISA Kits), and Brap regulates the dynamic MAPK (show MAPK1 ELISA Kits) signaling threshold in a spatially dependent fashion.
p21 Ras/Imp regulate cytokine production and migration in CD4 (show CD4 ELISA Kits) T cells
The protein encoded by this gene was identified by its ability to bind to the nuclear localization signal of BRCA1 and other proteins. It is a cytoplasmic protein which may regulate nuclear targeting by retaining proteins with a nuclear localization signal in the cytoplasm.
BRCA1 associated protein
, BRCA1-associated protein
, BRCA1-associated protein-like
, brca1-associated protein
, RING finger protein 52
, galectin-2-binding protein
, impedes mitogenic signal propagation
, renal carcinoma antigen NY-REN-63