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BRF2, Subunit of RNA Polymerase III Transcription Initiation Factor, BRF1-Like Proteins (BRF2)

BRF2 encodes one of the multiple subunits of the RNA polymerase III transcription factor complex required for transcription of genes with promoter elements upstream of the initiation site. Additionally we are shipping BRF2, Subunit of RNA Polymerase III Transcription Initiation Factor, BRF1-Like Antibodies (47) and BRF2, Subunit of RNA Polymerase III Transcription Initiation Factor, BRF1-Like Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
BRF2 55290 Q9HAW0
BRF2 306542 Q4V8D6
BRF2 66653 Q3UAW9
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Top BRF2, Subunit of RNA Polymerase III Transcription Initiation Factor, BRF1-Like Proteins at antibodies-online.com

Showing 8 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$3,023.17
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,157.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,173.50
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$3,179.00
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

BRF2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus)

Mouse (Murine)

More Proteins for BRF2, Subunit of RNA Polymerase III Transcription Initiation Factor, BRF1-Like (BRF2) Interaction Partners

Human BRF2, Subunit of RNA Polymerase III Transcription Initiation Factor, BRF1-Like (BRF2) interaction partners

  1. Study solved crystal structures of a human Brf2-TATA-binding complex bound to natural promoters, obtaining a detailed view of the molecular interactions occurring at Brf2-dependent Pol III promoters and highlighting the general structural and functional conservation of human Pol II and Pol III pre-initiation complexes.

  2. hnRNP F (show HNRNPF Proteins) is a co-factor in a subset of tristetraprolin (show ZFP36 Proteins)/BRF1 (show ZFP36L1 Proteins)/BRF2 (show ZFP36L2 Proteins)-mediated mRNA decay.

  3. These results suggested that BRF2 (show ZFP36L2 Proteins) overexpression in tumor tissues is significantly associated with the poor prognosis of NSCLC patients through promoting epithelial-mesenchymal transition (EMT (show ITK Proteins)) program.

  4. BRF2 (show ZFP36L2 Proteins) may have a role in poor prognosis and anti-angiogenic therapy for early-stage non-small cell lung cancer

  5. High expression of BRF2 (show ZFP36L2 Proteins) is closely associated with tumor progression, angiogenesis, and poor survival in esophageal squamous cell cancer.

  6. BRF2 (show ZFP36L2 Proteins) can serve as a marker for lung squamous cell carcinoma and may provide a novel target for therapy.

  7. C-terminal domain of Brf2 is required for efficient association of the protein with U6 promoter-bound TBP and SNAP(c), a type 3 promoter-specific transcription factor, and for efficient recruitment of Bdp1

  8. deregulation of Brf1 and Brf2 expression could be a key mechanism responsible for the observed deregulation of RNA pol III transcription in cancer cells

BRF2, Subunit of RNA Polymerase III Transcription Initiation Factor, BRF1-Like (BRF2) Protein Profile

Protein Summary

This gene encodes one of the multiple subunits of the RNA polymerase III transcription factor complex required for transcription of genes with promoter elements upstream of the initiation site. The product of this gene, a TFIIB-like factor, is directly recruited to the TATA-box of polymerase III small nuclear RNA gene promoters through its interaction with the TATA-binding protein.

Gene names and symbols associated with BRF2

  • BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like (BRF2)
  • zinc finger protein 36, C3H type-like 2 (ZFP36L2)
  • BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit (BRF2)
  • BRF2, RNA polymerase III transcription initiation factor 50 subunit (Brf2)
  • BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like (Brf2)
  • BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like (brf2)
  • 2700059M06Rik protein
  • 5730512K07Rik protein
  • AU018504 protein
  • AU022602 protein
  • BRF2 protein
  • BRFU protein
  • si:ch211-271b8.2 protein
  • TFIIIB50 protein
  • wu:fj22c04 protein
  • ZFP36L2 protein
  • zgc:100856 protein

Protein level used designations for BRF2

BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like , RNA polymerase III transcription initiation factor BRF2 , zinc finger protein 36, C3H type-like 2 , transcription factor IIIB 50 kDa subunit-like , B-related factor 2 , BRF-2 , RNA polymerase III transcription initiation factor BRFU , hBRFU , hTFIIIB50 , transcription factor IIB- related factor, TFIIIB50 , transcription factor IIIB 50 kDa subunit

GENE ID SPECIES
426772 Gallus gallus
698758 Macaca mulatta
746619 Pan troglodytes
100057924 Equus caballus
100385147 Callithrix jacchus
55290 Homo sapiens
306542 Rattus norvegicus
608026 Canis lupus familiaris
512789 Bos taurus
66653 Mus musculus
445142 Danio rerio
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