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The C-terminus of the protein encoded by BTBD2 binds topoisomerase I. Additionally we are shipping BTBD2 Antibodies (18) and many more products for this protein.
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Interaction of BTBD1 (show BTBD1 Proteins) and BTBD2 with TOP1 (show TOP1 Proteins) requires TOP1 (show TOP1 Proteins) residues 236 and 237, the same residues required to enhance the infectivity of progeny virions when TOP1 (show TOP1 Proteins) is expressed in African Green Monkey producer cells.
Polymorphisms in the LIG4, BTBD2, HMGA2, and RTEL1 genes, which are involved in the double-strand break repair pathway, are associated with glioblastoma multiforme survival.
subcellular colocalization of BTBD1 (show BTBD1 Proteins) and BTBD2 to cytoplasmic bodies; TRIM5delta colocalized with BTBD1 (show BTBD1 Proteins)/2 and appeared to serve as a scaffold for the assembly of endogenous BTBD1 (show BTBD1 Proteins)/2 proteins
The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies.
BTB (POZ) domain-containing protein 2
, BTB (POZ) domain containing 2
, BTB (POZ) domain containing 2-like
, BTB/POZ domain-containing protein 2-like
, BTB domain protein 2
, BTB/POZ domain-containing protein 2