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anti-BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) Antibodies

BACH1 encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). Additionally we are shipping BACH1 Proteins (5) and BACH1 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BACH1 12013 P97302
BACH1 571 O14867
BACH1 304127  
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Top anti-BACH1 Antibodies at antibodies-online.com

Showing 10 out of 103 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-BACH1 Antibody Titration: 1.25ug/mlELISA Titer: 1:1562500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated EIA, WB BACH1 Antibody (C-term) western blot analysis in ZR-75-1 cell line lysates (35µg/lane).This demonstrates the BACH1 antibody detected the BACH1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from HepG2 cells, using BACH1 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of HeLa cells, using BACH1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated WB BACH1 monoclonal antibody (M02), clone 1B8 Western Blot analysis of BACH1 expression in NIH/3T3. Detection limit for recombinant GST tagged BACH1 is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB BACH1 Antibody (C-term) (ABIN658569) western blot analysis in ZR-75-1 cell line lysates (35 µg/lane). This demonstrates the BACH1 antibody detected the BACH1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated FACS, IHC, IHC (p), WB Immunohistochemistry-Paraffin: BACH1 Antibody (4E11) [NBP2-01904] - Staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-BACH1 mouse monoclonal antibody. Flow Cytometry: BACH1 Antibody (4E11) [NBP2-01904] - HEK293T cells transfected with either overexpression plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-BACH1 antibody, and then analyzed by flow cytometry. 0.1 mL Log in to see 6 to 9 Days
$447.56
Details
Human Mouse Un-conjugated FACS, IHC, WB HEK293T cells transfected with either RC221628 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-BACH1 antibody (ABIN2455676), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BACH1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-BACH1. 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, WB 100 μL Log in to see 14 Days
$175.80
Details
Human Rabbit Un-conjugated IC, IF, IP, IHC, WB Immunofluorescent analysis of BACH1 staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of BACH1 staining in human tonsil formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 9 Days
$487.50
Details

BACH1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)
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Human , , ,
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Rat (Rattus)


Top referenced anti-BACH1 Antibodies

  1. Human Monoclonal BACH1 Primary Antibody for WB - ABIN394012 : Miyazaki, Kirino, Takeno, Samukawa, Hama, Tanaka, Yamaji, Ueda, Tomita, Fujita, Ishigatsubo: Expression of heme oxygenase-1 in human leukemic cells and its regulation by transcriptional repressor Bach1. in Cancer science 2010 (PubMed)
    Show all 5 references for ABIN394012

  2. Human Polyclonal BACH1 Primary Antibody for EIA, WB - ABIN950595 : Hou, Tian, Zheng, Bonkovsky: MicroRNA-196 represses Bach1 protein and hepatitis C virus gene expression in human hepatoma cells expressing hepatitis C viral proteins. in Hepatology (Baltimore, Md.) 2010 (PubMed)
    Show all 3 references for ABIN950595

  3. Human Polyclonal BACH1 Primary Antibody for IF, ELISA - ABIN1533488 : Ohira, Seki, Nagase, Ishikawa, Nomura, Ohara: Characterization of a human homolog (BACH1) of the mouse Bach1 gene encoding a BTB-basic leucine zipper transcription factor and its mapping to chromosome 21q22.1. in Genomics 1998 (PubMed)
    Show all 2 references for ABIN1533488

  4. Human Monoclonal BACH1 Primary Antibody for FACS, IHC - ABIN4282846 : Cha, Lee, Han, Kim, Kang, Choi, Cho: MicroRNA alteration and putative target genes in high-grade prostatic intraepithelial neoplasia and prostate cancer: STAT3 and ZEB1 are upregulated during prostate carcinogenesis. in The Prostate 2016 (PubMed)

  5. Human Polyclonal BACH1 Primary Antibody for WB - ABIN2780352 : Litman, Peng, Jin, Zhang, Zhang, Powell, Andreassen, Cantor: BACH1 is critical for homologous recombination and appears to be the Fanconi anemia gene product FANCJ. in Cancer cell 2005 (PubMed)

More Antibodies against BACH1 Interaction Partners

Zebrafish BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) interaction partners

  1. Bach1 regulates the liver specificity and transience of the Nrf2a (show NFE2L2 Antibodies)-dependent induction of hmox1a and that heme mediates this regulation through Bach1 inhibition based on its level in each tissue.

  2. The Bach1b-MafK heterodimer represses the zymogen promoters, whereas the Nrf2a-MafK heterodimer activates them.

Mouse (Murine) BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) interaction partners

  1. These results suggest that Bach1 and Bach2 (show BACH2 Antibodies) work in a complementary manner to maintain the normal function of the AMs (show MAT1A Antibodies) and surfactant homeostasis in the lung.

  2. By integrating the chromatin immunoprecipitation and next-generation sequencing data with a comparative analysis of gene expression in Bach1-deficient and wild type immortalized mouse embryonic fibroblasts (iMEFs), study found 35 new genes whose expression was repressed by BACH1. Known functions of some of these genes suggested a role of BACH1 in adipocyte differentiation, which was verified using iMEFs.

  3. Bach1 deficiency reduces the severity of osteoarthritis-like changes. This may be due to maintenance of cartilage homeostasis and joint health by antioxidant effects

  4. Bach1 suppresses angiogenesis after ischemic injury and impairs Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling by disrupting the interaction between beta-catenin (show CTNNB1 Antibodies) and TCF4 (show TCF4 Antibodies) and by recruiting histone deacetylase 1 (show HDAC1 Antibodies) to the promoter of TCF4 (show TCF4 Antibodies)-targeted genes.

  5. Bach1 deficiency and accompanying overexpression of HO-1 (show HMOX1 Antibodies) did not influence aging or p53 (show TP53 Antibodies) deficiency-driven tumorigenesis.

  6. Our results suggest that Bach2 (show BACH2 Antibodies) functions with Bach1 and EBF1 (show EBF1 Antibodies) to promote B cell development by repressing myeloid genes in common lymphoid progenitor cells

  7. HO-1 (show HMOX1 Antibodies) induction after ischemia was associated to down-regulation of transcriptional repressor Bach-1, and induction of HO-1 (show HMOX1 Antibodies) when HO enzymatic activity was inhibited was related to worst outcome after brain ischemia.

  8. Bach1 deficiency ameliorates TNBS colitis.

  9. Our data provide evidence for a critical role of Bach1 in cell transformation and tumor growth induced by activated H-Ras (show HRAS Antibodies)(V12).

  10. apoptosis rate was significantly lower at 1 and 2 weeks post-puncture in Bach 1-/- mice

Human BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) interaction partners

  1. BACH1 down-regulation in HT29 colon cancer cells had no effect on cell growth but did inhibit cell migration by decreasing metastasis-related genes expression.

  2. This study indicates that the expression of BACH1 could be elevated as a compensatory mechanism to decrease the globin chain imbalance as well as to reduce the oxidative stress found in hemoglobin E/beta-thalassemia.

  3. A short while ago some studies suggested that BACH1 is involved in cancers, especially breast cancer. This factor is mentioned as a novel master regulator which adjusts several genes involved in bone metastasis of breast cancer, especially CXCR4 (show CXCR4 Antibodies) and MMP1 (show MMP1 Antibodies), two main genes in the enhancement of cancer cell migration and invasion to distant organs. [Review]

  4. Bach1 suppresses cell proliferation and induces cell-cycle arrest and apoptosis.

  5. Induction of GSH-related genes xCT (show SLC7A11 Antibodies) and GCLM (show GCLM Antibodies) were oxygen and Bach1-insensitive during long-term culture under 5% O2, providing the first evidence that genes related to GSH synthesis mediate protection afforded by Nrf2 (show GABPA Antibodies)-Keap1 (show KEAP1 Antibodies) defense pathway

  6. heme oxygenase-1 (show HMOX1 Antibodies) expression is induced by gold nanoparticles through Nrf2 (show GABPA Antibodies) activation and Bach1 export in human vascular endothelial cells

  7. Cyanidin-3-O-glucoside protects HUVECs from palmitic acid-induced injuryby modulating the balance of Nrf2 (show GABPA Antibodies) versus Bach1 inside the nucleus so influencing upregulation of electrophile responsive element mediated gene expression.

  8. sensitizer-induced up-regulation of both the endogenous HMOX1 (show HMOX1 Antibodies) and the luciferase constructs under the control of the HMOX1 (show HMOX1 Antibodies)-ARE or the full HMOX1 (show HMOX1 Antibodies) promoter appear to be under the control of both Nrf2 (show GABPA Antibodies) and Bach1.

  9. This study demonstrated that Bach1 overexpression in Down syndrome correlates with the alteration of the HO-1 (show HMOX1 Antibodies)/BVR-a (show BLVRA Antibodies) system.

  10. Bach1 suppresses angiogenesis after ischemic injury and impairs Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling by disrupting the interaction between beta-catenin (show CTNNB1 Antibodies) and TCF4 (show TCF4 Antibodies) and by recruiting histone deacetylase 1 (show HDAC1 Antibodies) to the promoter of TCF4 (show TCF4 Antibodies)-targeted genes.

BACH1 Antigen Profile

Protein Summary

This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene.

Gene names and symbols associated with BACH1

  • BTB and CNC homology 1, basic leucine zipper transcription factor 1 (BACH1) antibody
  • BTB and CNC homology 1, basic leucine zipper transcription factor 1 (bach1) antibody
  • BTB and CNC homology 1 (Bach1) antibody
  • BTB and CNC homology 1, basic leucine zipper transcription factor 1 (Bach1) antibody
  • 6230421P05Rik antibody
  • AI323795 antibody
  • BACH-1 antibody
  • BACH1 antibody
  • zgc:112205 antibody

Protein level used designations for BACH1

BTB and CNC homology 1 transcription factor , BTB and CNC homology 1, basic leucine zipper transcription factor 1 , basic leucine zipper transcription factor 1 , transcription regulator protein BACH1-like , BTB and CNC homolog 1 , transcription regulator protein BACH1 , HA2303 , basic region leucine zipper transcriptional regulator BACH1

GENE ID SPECIES
418488 Gallus gallus
487718 Canis lupus familiaris
531350 Bos taurus
100523514 Sus scrofa
553688 Danio rerio
705817 Macaca mulatta
745234 Pan troglodytes
100053654 Equus caballus
100125783 Xenopus (Silurana) tropicalis
100353797 Oryctolagus cuniculus
100385069 Callithrix jacchus
100448413 Pongo abelii
100464674 Ailuropoda melanoleuca
100549402 Meleagris gallopavo
100595281 Nomascus leucogenys
12013 Mus musculus
571 Homo sapiens
304127 Rattus norvegicus
Selected quality suppliers for anti-BACH1 (BACH1) Antibodies
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