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BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) ELISA Kits

BACH1 encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). Additionally we are shipping BACH1 Antibodies (103) and BACH1 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse BACH1 BACH1 12013 P97302
BACH1 571 O14867
Anti-Rat BACH1 BACH1 304127  
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Top BACH1 ELISA Kits at antibodies-online.com

Showing 1 out of 2 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 9.375 pg/mL 37.5-2400 pg/mL Typical standard curve 96 Tests Log in to see 11 to 13 Days
$910.56
Details

More ELISA Kits for BACH1 Interaction Partners

Zebrafish BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) interaction partners

  1. Bach1 regulates the liver specificity and transience of the Nrf2a (show NFE2L2 ELISA Kits)-dependent induction of hmox1a and that heme mediates this regulation through Bach1 inhibition based on its level in each tissue.

  2. The Bach1b-MafK heterodimer represses the zymogen promoters, whereas the Nrf2a-MafK heterodimer activates them.

Mouse (Murine) BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) interaction partners

  1. Bach1 siRNA exerts protective effects against bleomycin-induced pulmonary fibrosis in mice.

  2. These results suggest that Bach1 and Bach2 work in a complementary manner to maintain the normal function of the AMs (show MAT1A ELISA Kits) and surfactant homeostasis in the lung.

  3. By integrating the chromatin immunoprecipitation and next-generation sequencing data with a comparative analysis of gene expression in Bach1-deficient and wild type immortalized mouse embryonic fibroblasts (iMEFs), study found 35 new genes whose expression was repressed by BACH1. Known functions of some of these genes suggested a role of BACH1 in adipocyte differentiation, which was verified using iMEFs.

  4. Bach1 deficiency reduces the severity of osteoarthritis-like changes. This may be due to maintenance of cartilage homeostasis and joint health by antioxidant effects

  5. Bach1 suppresses angiogenesis after ischemic injury and impairs Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling by disrupting the interaction between beta-catenin (show CTNNB1 ELISA Kits) and TCF4 (show TCF4 ELISA Kits) and by recruiting histone deacetylase 1 (show HDAC1 ELISA Kits) to the promoter of TCF4 (show TCF4 ELISA Kits)-targeted genes.

  6. Bach1 deficiency and accompanying overexpression of HO-1 (show HMOX1 ELISA Kits) did not influence aging or p53 (show TP53 ELISA Kits) deficiency-driven tumorigenesis.

  7. Our results suggest that Bach2 functions with Bach1 and EBF1 (show EBF1 ELISA Kits) to promote B cell development by repressing myeloid genes in common lymphoid progenitor cells

  8. HO-1 (show HMOX1 ELISA Kits) induction after ischemia was associated to down-regulation of transcriptional repressor Bach-1, and induction of HO-1 (show HMOX1 ELISA Kits) when HO enzymatic activity was inhibited was related to worst outcome after brain ischemia.

  9. Bach1 deficiency ameliorates TNBS colitis.

  10. Our data provide evidence for a critical role of Bach1 in cell transformation and tumor growth induced by activated H-Ras (show HRAS ELISA Kits)(V12).

Human BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) interaction partners

  1. BACH1 down-regulation in HT29 colon cancer cells had no effect on cell growth but did inhibit cell migration by decreasing metastasis-related genes expression.

  2. This study indicates that the expression of BACH1 could be elevated as a compensatory mechanism to decrease the globin chain imbalance as well as to reduce the oxidative stress found in hemoglobin E/beta-thalassemia.

  3. A short while ago some studies suggested that BACH1 is involved in cancers, especially breast cancer. This factor is mentioned as a novel master regulator which adjusts several genes involved in bone metastasis of breast cancer, especially CXCR4 (show CXCR4 ELISA Kits) and MMP1 (show MMP1 ELISA Kits), two main genes in the enhancement of cancer cell migration and invasion to distant organs. [Review]

  4. Bach1 suppresses cell proliferation and induces cell-cycle arrest and apoptosis.

  5. Induction of GSH-related genes xCT (show SLC7A11 ELISA Kits) and GCLM (show GCLM ELISA Kits) were oxygen and Bach1-insensitive during long-term culture under 5% O2, providing the first evidence that genes related to GSH synthesis mediate protection afforded by Nrf2 (show GABPA ELISA Kits)-Keap1 (show KEAP1 ELISA Kits) defense pathway

  6. heme oxygenase-1 (show HMOX1 ELISA Kits) expression is induced by gold nanoparticles through Nrf2 (show GABPA ELISA Kits) activation and Bach1 export in human vascular endothelial cells

  7. Cyanidin-3-O-glucoside protects HUVECs from palmitic acid-induced injuryby modulating the balance of Nrf2 (show GABPA ELISA Kits) versus Bach1 inside the nucleus so influencing upregulation of electrophile responsive element mediated gene expression.

  8. sensitizer-induced up-regulation of both the endogenous HMOX1 (show HMOX1 ELISA Kits) and the luciferase constructs under the control of the HMOX1 (show HMOX1 ELISA Kits)-ARE or the full HMOX1 (show HMOX1 ELISA Kits) promoter appear to be under the control of both Nrf2 (show GABPA ELISA Kits) and Bach1.

  9. This study demonstrated that Bach1 overexpression in Down syndrome correlates with the alteration of the HO-1 (show HMOX1 ELISA Kits)/BVR-a (show BLVRA ELISA Kits) system.

  10. Bach1 suppresses angiogenesis after ischemic injury and impairs Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling by disrupting the interaction between beta-catenin (show CTNNB1 ELISA Kits) and TCF4 (show TCF4 ELISA Kits) and by recruiting histone deacetylase 1 (show HDAC1 ELISA Kits) to the promoter of TCF4 (show TCF4 ELISA Kits)-targeted genes.

BACH1 Antigen Profile

Antigen Summary

This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene.

Gene names and symbols associated with BACH1

  • BTB and CNC homology 1, basic leucine zipper transcription factor 1 (BACH1) antibody
  • BTB and CNC homology 1, basic leucine zipper transcription factor 1 (bach1) antibody
  • BTB and CNC homology 1 (Bach1) antibody
  • BTB and CNC homology 1, basic leucine zipper transcription factor 1 (Bach1) antibody
  • 6230421P05Rik antibody
  • AI323795 antibody
  • BACH-1 antibody
  • BACH1 antibody
  • zgc:112205 antibody

Protein level used designations for BACH1

BTB and CNC homology 1 transcription factor , BTB and CNC homology 1, basic leucine zipper transcription factor 1 , basic leucine zipper transcription factor 1 , transcription regulator protein BACH1-like , BTB and CNC homolog 1 , transcription regulator protein BACH1 , HA2303 , basic region leucine zipper transcriptional regulator BACH1

GENE ID SPECIES
418488 Gallus gallus
487718 Canis lupus familiaris
531350 Bos taurus
100523514 Sus scrofa
553688 Danio rerio
705817 Macaca mulatta
745234 Pan troglodytes
100053654 Equus caballus
100125783 Xenopus (Silurana) tropicalis
100353797 Oryctolagus cuniculus
100385069 Callithrix jacchus
100448413 Pongo abelii
100464674 Ailuropoda melanoleuca
100549402 Meleagris gallopavo
100595281 Nomascus leucogenys
12013 Mus musculus
571 Homo sapiens
304127 Rattus norvegicus
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