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BPI encodes a lipopolysaccharide binding protein. Additionally we are shipping BPI Antibodies (90) and BPI Kits (29) and many more products for this protein.
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Findings suggest that residue Asp190 combined with surrounding positively charged residues largely contribute to bactericidal and endotoxin-neutralizing activities of bactericidal/permeability-increasing protein (BPI) mBPI5.
Data suggest that BPI is expressed in testis and epididymis (but not in seminal vesicles, prostate, or solidification glands); BPI expression in epididymis is up-regulated by testosterone; BPI may participate in process of sperm-oocyte interaction.
The mouse neutrophils store BPI with antibacterial activity and that murine BPI is also expressed in testis and epididymis.
the requirement for C/EBP epsilon (show CEBPE Proteins) in mediating BPI gene expression in myeloid cells in vitro and in vivo.
data demonstrate that murine BPI is a potent LPS (show TLR4 Proteins)-neutralizing protein that may limit innate immune responses during Gram-negative infections
BPI G645A polymorphism was associated with a decreased risk of ulcerative colitis; the BPI G645A polymorphism was not associated with the risk of crohn's disease.
Bactericidal permeability increasing protein Lys216Glu polymorphism is associated with both Crohn's disease and ulcerative colitis.
MPO (show MPO Proteins) and BPI in CD4 (show CD4 Proteins)(+)T-lymphocytes, and PDHA1 (show PDHA1 Proteins) and MRPL42 (show MRPL42 Proteins) in CD8 (show CD8A Proteins)(+) T-lymphocytes might be used as specific biomarkers of severe asthma progression.
This review article focuses on the structural and functional properties of BPI with respect to its antimicrobial contribution to host defense during GNB infections and endotoxin-induced inflammation.
Diminished PRRs, IFN-signature, and BPI gene expression raises the possibility that impairments in these pathways contribute to the susceptibility of LBW term infants to infection.
Lung function and IgA-BPI-ANCA, but not Leeds criteria, were significantly associated with adverse outcome.
BPI mutation (PstI (show SPINK1 Proteins) in intron 5) and a decreased plasma BPI level were significant risk factors in susceptibility to COPD (show ARCN1 Proteins)...BPI genetic mutation and impaired BPI production or release may result in airflow obstruction in smokers.
The bactericidal/permeability-increasing protein in the innate defence of the lower airways
there is a correlation between the presence of BPI-ANCA, the properties of the colonizing bacteria and the clinical conditions of the host in cystic fibrosis (show S100A8 Proteins)
Restriction enzyme digestion and DNA sequence analysis revealed that the sequence encoding signal peptide and bioactive N-terminal fragment of BPI had six nucleotide substitutions, compared with that of the established human BPI sequence
Polymorphism in BPI has no effect on daughter yield deviation for somatic cell score in Holstein cattle.
p15 (show CDKN2B Proteins) proteins are stored in the specific (secondary) granules of rabbit neutrophils and are secreted extracellularly after inflammatory stimulation.
The p15 (show CDKN2B Proteins) proteins exhibit antimicrobial synergy with another rabbit cathelicidin (CAP-18) and with the rabbit Bactericidal/permeability-increasing protein (BPI).
the BPI protein expres-sion levels in the E. coli F18 (show MAMLD1 Proteins)-resistant group were significantly higher than those in the sensitive group, indicating that high BPI protein ex-pression is associated with resistance to E. coli F18 (show MAMLD1 Proteins)
BPI expression is improved by demethylation of the BPI gene upstream CpG island.
The expression of the BPI gene of Sutai piglets ranging from newborn to post-weaning days 8, 18, 30, and 35, was analyzed.
Upregulation of porcine BPI gene expression in the small intestines plays a direct role in resistance to ETEC F18 (show MAMLD1 Proteins) infection.
In jejunum and duodenum, the expression of BPI gene in resistant pig was significant higher than that in the sensitive pig.
This gene encodes a lipopolysaccharide binding protein. It is associated with human neutrophil granules and has bactericidal activity on gram-negative organisms.
bactericidal permeability-increasing protein
, bactericidal/permeability-increasing protein
, BPI fold containing family D, member 1
, CAP 57
, recombinant BPI holoprotein, rBPI
, bactericidal/permeability increasing protein