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Baculoviral IAP Repeat-Containing 7 Proteins (BIRC7)

The protein encoded by BIRC7 is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. Additionally we are shipping Baculoviral IAP Repeat-Containing 7 Antibodies (140) and Baculoviral IAP Repeat-Containing 7 Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
BIRC7 107768  
BIRC7 79444 Q96CA5
Rat BIRC7 BIRC7 296468  
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Top Baculoviral IAP Repeat-Containing 7 Proteins at antibodies-online.com

Showing 10 out of 18 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 16 Days
$250.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,999.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$467.86
Details
HOST_Escherichia coli (E. coli) Mouse His tag   1 mg Log in to see 3 to 4 Days
$4,009.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 μg Log in to see 6 to 11 Days
$142.86
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 19 Days
$785.40
Details

BIRC7 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

Top referenced Baculoviral IAP Repeat-Containing 7 Proteins

  1. Human BIRC7 Protein expressed in Escherichia coli (E. coli) - ABIN667709 : Ashhab, Alian, Polliack, Panet, Ben Yehuda: Two splicing variants of a new inhibitor of apoptosis gene with different biological properties and tissue distribution pattern. in FEBS letters 2001 (PubMed)
    Show all 2 references for ABIN667709

More Proteins for Baculoviral IAP Repeat-Containing 7 (BIRC7) Interaction Partners

Mouse (Murine) Baculoviral IAP Repeat-Containing 7 (BIRC7) interaction partners

  1. Data showed that Livin knock-down suppressed cell proliferation and inhibited cell invasion, accompanied by downregulation of VEGF (show VEGFA Proteins) and MMP-2 (show MMP2 Proteins)/-9. Its silencing resulted in the prevention of xenograft tumor formation.

  2. Birc7 is a late fiber gene of the mouse lens. Its expression in cells bordering the OFZ is consistent with a role in organelle degradation, a process in which the ubiquitin proteasome pathway has been implicated previously.

  3. ML-IAP is dispensable for both normal mouse development and ocular homoeostasis.

Human Baculoviral IAP Repeat-Containing 7 (BIRC7) interaction partners

  1. Our results suggested the important role of Livin and its partner molecule in the process of VSV treatment

  2. Data showed that Livin knock-down suppressed cell proliferation and inhibited cell invasion, accompanied by downregulation of VEGF (show VEGFA Proteins) and MMP-2 (show MMP2 Proteins)/-9. Its silencing resulted in the prevention of xenograft tumor formation.

  3. These findings suggest that livin may be used as a novel target for tumor gene therapy.

  4. Upregulation of Livin expression and downregulation of caspase (show CASP3 Proteins) activity are observed under cycling and chronic hypoxia in glioblastoma cells and xenografts.

  5. Livin expression was higher in condyloma acuminatum than in normal cells and was correlated with survivin (show BIRC5 Proteins) and Ki-67 (show MKI67 Proteins).

  6. Livin gene has a high expression in osteosarcoma and inhibits apoptosis in tumor tissue.

  7. livin is associated with invasive and oncogenic phenotypes such as tumor cell invasion, tumor cell migration, tumor cell proliferation, and resistance to apoptosis in human oral squamous cell carcinoma cells.

  8. These data suggest that livin overexpression plays an important role in tumor invasiveness by mediating resistance to apoptosis.

  9. effectively silence Livin gene expression in LoVo colon cancer cells, inhibit cell proliferation and colony formation, induce apoptosis, and enhance sensitivity to cisplatin

  10. In diagnostically difficult cases of diffuse large B-cell lymphoma and Hodgkin lymphoma, focus on livin as marker may provide useful corroborative information.

Baculoviral IAP Repeat-Containing 7 (BIRC7) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide.

Gene names and symbols associated with BIRC7

  • baculoviral IAP repeat-containing 5-like (Birc5l)
  • baculoviral IAP repeat containing 7 (BIRC7)
  • baculoviral IAP repeat-containing 7 (birc7)
  • baculoviral IAP repeat containing 7 (birc7)
  • baculoviral IAP repeat-containing 7 (Birc7)
  • baculoviral IAP repeat-containing 7 (livin) (Birc7)
  • E130019N06 protein
  • EIAP/XLX protein
  • KIAP protein
  • Livin protein
  • ML-IAP protein
  • MLIAP protein
  • RGD1562883 protein
  • RNF50 protein
  • TIAP2 protein
  • xEIAP protein
  • XLX protein
  • zgc:165605 protein

Protein level used designations for BIRC7

baculoviral IAP repeat-containing 5-like , baculoviral IAP repeat-containing 7 , baculoviral IAP repeat-containing 7 (livin) , E3 ubiquitin-protein ligase EIAP , Embryonic/Egg IAP , baculoviral IAP repeat-containing protein 7 , RING finger protein 50 , kidney inhibitor of apoptosis protein , livin inhibitor of apoptosis , melanoma inhibitor of apoptosis protein

GENE ID SPECIES
107768 Mus musculus
419239 Gallus gallus
485969 Canis lupus familiaris
514508 Bos taurus
697671 Macaca mulatta
100073331 Danio rerio
100127811 Xenopus (Silurana) tropicalis
79444 Homo sapiens
296468 Rattus norvegicus
329581 Mus musculus
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